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Catalog Number: (10781-968)
Supplier: Biosensis
Description: Presenilin-2 (PSEN2) is a multi-pass membrane protein and component of the gamma-secretase complex. Defects in PSEN2 are a cause of Alzheimer disease type 4 (AD4), an autosomal dominant Alzheimer disease. (Ref:SWISS-Prot).


Catalog Number: (10782-660)
Supplier: Biosensis
Description: FUNCTION: Seems to promotes the survival of visceral and proprioceptive sensory neurons. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Brain and peripheral tissues. SIMILARITY: Belongs to the NGF-beta family.


Catalog Number: (76265-480)
Supplier: Biosensis
Description: The capsaicin receptor (VR1, TRPV1) is a ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. The receptor seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. It is involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits a time- and Ca2+-dependent outward rectification, followed by a long-lasting refractory state. Mild extracellular acidic pH (6.5) potentiates channel activation by noxious heat and vanilloids, whereas acidic conditions (pH less than 6) directly activate the channel. Can be activated by endogenous compounds, including 12-hydroperoxytetraenoic acid and bradykinin. Acts as ionotropic endocannabinoid receptor with central neuromodulatory effects. Triggers a form of long-term depression (TRPV1-LTD) mediated by the endocannabinoid anandamine in the hippocampus and nucleus accumbens by affecting AMPA receptors endocytosis (Ref: uniprot.org). Antibody is specific for rat/mouse VR1 protein in westerns and immunofluorescent immunohistochemistry on mouse PEG fixed DRG tissues. Pre-absorption with immunogen obliterates positive staining. Cross reactivity with other non-VR1 proteins is minimal; cross reactivity with VR1 from other species not yet tested.


Catalog Number: (78026-530)
Supplier: Biosensis
Description: LIPID STAIN LIPOFLUORER2 1000X 550UL PK4

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Catalog Number: (78026-519)
Supplier: Biosensis
Description: FLUORESCENT STAIN ORANGE NISSLFLUOR 40ML

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Catalog Number: (78026-536)
Supplier: Biosensis
Description: STAIN FLUOR NISSL NISSLFLUOR 10ML PK4

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Catalog Number: (76545-450)
Supplier: Biosensis
Description: KIT ELISA HUMAN MATURE NGF/PRONGF COMBO


Catalog Number: (76545-434)
Supplier: Biosensis
Description: KIT ELISA BOVINE A1 BETA CASEIN


Catalog Number: (78026-510)
Supplier: Biosensis
Description: ELISA KIT CYSTATIN-C HU RAPID 1P

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Catalog Number: (78026-526)
Supplier: Biosensis
Description: LIPID STAIN LIPOFLUOR MR 1000X 550UL PK4

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Catalog Number: (76545-452)
Supplier: Biosensis
Description: KIT ELISA MOUSE MATURE NGF/PRONGF COMBO


Catalog Number: (78026-528)
Supplier: Biosensis
Description: LIPID STAIN LIPOFLUOR P2 1000X 550UL PK4

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Catalog Number: (76545-436)
Supplier: Biosensis
Description: KIT ELISA BOVINE A1 BETA CASEIN


Catalog Number: (76545-442)
Supplier: Biosensis
Description: KIT ELISA BOVINE A2 BETA CASEIN


Catalog Number: (78026-515)
Supplier: Biosensis
Description: ANTIBODY NF-L DS-SENSOR 6H63 MONO 50UG

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Catalog Number: (78026-511)
Supplier: Biosensis
Description: ELISA KIT CYSTATIN-C HU RAPID 2P

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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