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Product Image-10104-394

Anti-IQCE Rabbit Polyclonal Antibody

Catalog Number: (10104-394)
Supplier: Prosci
Description: IQCE contains 2 IQ domains. The functions of IQCE remain unknown.
Image Unavailable-75794-232

Human Recombinant CD83 non-lytic (from CHO Cells)

Catalog Number: (75794-232)
Supplier: Prosci
Description: Human CD83 is a 40-50 kDa member of the Siglec (or sialic-acid-binding immunoglobulin-like lectin) family of transmembrane proteins. CD83 is a primary marker for dendritic cells. It is also found on B cells, neutrophils, monocytes and macrophages. Except for dendritic cells, CD83 expression is often transient. CD83 binds to sialic acids on target cells. Membrane CD83 promotes T cell proliferation, particularly of CD8+ cytotoxic T cells. Soluble CD83 is immunosuppressive and blocks T cell activation. On monocytes, CD83 is suggested to drive monocytes into a fibrocyte phenotype. A lack of membrane-expressed CD83 leads to an unusual IL-4/ IL-10 producing CD4+ T cell phenotype.
Product Image-10102-424

Anti-FZD9 Rabbit Polyclonal Antibody

Catalog Number: (10102-424)
Supplier: Prosci
Description: FZD9 contains 1 FZ (frizzled) domain and belongs to the G-protein coupled receptor Fz/Smo family. It is receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members. It may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney.
Image Unavailable-76194-984

Anti-KRT10 Mouse Monoclonal Antibody [clone: CTKN10-1]

Catalog Number: (76194-984)
Supplier: Prosci
Description: Keratin-10 is a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21. Keratin 10 has been shown to interact with AKT1. [Wiki]
Product Image-10097-946

Anti-IL21 Rabbit Polyclonal Antibody

Catalog Number: (10097-946)
Supplier: Prosci
Description: Polyclonal, Host: Rabbit, Species reacivity: human, Immunogen: Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hIGF-BP7, Tested application: ELISA, WB
Product Image-76011-770

Anti-AQP5 Rabbit Polyclonal Antibody

Catalog Number: (76011-770)
Supplier: Prosci
Description: Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13.
Image Unavailable-77120-572

His-tag Peptide

Catalog Number: (77120-572)
Supplier: Prosci
Description: His-tag Peptide
Image Unavailable-77132-038

Human Recombinant ROR2 Protein (from HEK293 Cells)

Catalog Number: (77132-038)
Supplier: Prosci
Description: Human Recombinant ROR2 Protein (from HEK293 Cells)
Product Image-75793-056

Anti-TNFRSF10A Mouse Monoclonal Antibody (ATTO 488) [clone: HS101]

Catalog Number: (75793-056)
Supplier: Prosci
Description: TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
Image Unavailable-10766-058

Anti-CD40 Hamster Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: HM40-3]

Catalog Number: (10766-058)
Supplier: Prosci
Description: The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The HM40-3 antibody blocks the binding of CD40L (CD154) and stimulates B and dendritic cell proliferation.
Product Image-76011-406

Anti-EDN1 Rabbit Polyclonal Antibody

Catalog Number: (76011-406)
Supplier: Prosci
Description: The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.
Product Image-76012-592

Anti-LUZP2 Rabbit Polyclonal Antibody

Catalog Number: (76012-592)
Supplier: Prosci
Description: The specific function of this protein remains unknown.
Product Image-76010-308

Anti-GLTSCR1 Rabbit Polyclonal Antibody

Catalog Number: (76010-308)
Supplier: Prosci
Description: For WB starting dilution is: 1:1000
Product Image-75792-860

Anti-NS5B Mouse Monoclonal Antibody [clone: 5B-3B1]

Catalog Number: (75792-860)
Supplier: Prosci
Description: The NS3 serine protease, in association with NS4A, is responsible for the cleavages of the Hepatitis C virus protease complexes NS3-NS4A, NS4A-NS4B, NS4B-NS5A and NS5A-NS5B. NS5B is a RNA-dependent RNA polymerase that plays an essential role in the virus replication. Hepatitis C virus protease NS3-NS4A colocalizes with IPS-1/VISA/MAVS/Cardif in the mitochondrial membrane and has been shown to cleave the TLR3 adapter TRIF and Cardif to eliminate the antiviral signaling pathways. NS3-NS4A represents an important target for anti-HCV drugs.
Product Image-10100-672

Anti-GATA1 Rabbit Polyclonal Antibody

Catalog Number: (10100-672)
Supplier: Prosci
Description: GATA1 is a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Product Image-89420-736

Human NALP10 Peptide (14 aa near N-terminus)

Catalog Number: (89420-736)
Supplier: Prosci
Description: NALP10 peptide is used for blocking the activity of NALP10 antibody.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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