You Searched For: PROSCI INCORPORATED

Catalog Number: (76009-834)

Supplier: Prosci

Description: May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids in the presence of calcium ions (By similarity).

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Catalog Number: (89416-864)

Supplier: Prosci

Description: KLRA1 Antibody: KLRA1 (also known and Ly49L) is a member of the LY49 family of receptors Natural killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA1 is thought to be an activating receptor, inducing DAP12 phosphorylation in response to antibody-mediated cross-linking of KLRA1 on NK cells. At least three isoforms of KLRA1 are known to exist.

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Catalog Number: (77125-752)

Supplier: Prosci

Description: CLCA1 Peptide

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Catalog Number: (89421-382)

Supplier: Prosci

Description: TCTEX1D3 peptide is used for blocking the activity of TCTEX1D3 antibody.

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Catalog Number: (10115-178)

Supplier: Prosci

Description: Polyclonal, Host: Goat; Target Species: Mouse; Immunogen: Ptgds antibody was raised against a 14 amino acid synthetic peptide near the internal region of Ptgds (mouse); Applications: ELISA,Western blotting

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Catalog Number: (10114-288)

Supplier: Prosci

Description: Polyclonal, Host: Goat; Immunogen: PRED6 antibody was raised against a 12 amino acid synthetic peptide near the internal region of PRED6; Applications: ELISA

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Catalog Number: (10078-388)

Supplier: Prosci

Description: Polyclonal antibody ATG4B Host: Rabbit Target Species: Mouse, Rat, Chicken, Frog, Fish, ZebrafishIsotype: IgG Immunogen: ATG4B antibody was raised against a portion of amino acid 350 - 400 of ATG4B (Human). Application: WB, IHC, ICC

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Supplier: Prosci

Description: BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residue and a propeptide of 110 amino acid residues. Recombinant human BDNF is a 27.0 kDa homodimer of two 119 amino acid subunits linked by strong non-covalent interactions. Human and Mouse BDNF sequences are identical.

Catalog Number: (10072-312)

Supplier: Prosci

Description: Methionine adenosyltransferase (EC 2.5.1.6) catalyzes the biosynthesis of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the major methyl donor for many of the transmethylation reactions in the body. The MAT2A promoter is highly GC rich, especially in the first 300 bp. The promoter contains several potential SP1-, v-myb-, and GATA-binding sites, as well as potential binding sites for C/EBP, HSF2, c-myb, and STATx. It can efficiently drive expression from a reporter gene in both Jurkat and 293 cells.

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Catalog Number: (89420-524)

Supplier: Prosci

Description: LYRM2 peptide is used for blocking the activity of LYRM2 antibody.

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Catalog Number: (10117-086)

Supplier: Prosci

Description: Polyclonal; Host: Goat; Species Reactiviy: Human; Immunogen: MARCH6 antibody was raised against a 12 amino acid synthetic peptide near the internal region of 40974; Application: ELISA, Western Blot

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Catalog Number: (76754-828)

Supplier: Prosci

Description: Anti-RGS17 Rabbit Polyclonal Antibody

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Catalog Number: (10116-254)

Supplier: Prosci

Description: Polyclonal antibody M6prbp1 Host: Goat Target Species: rat immunogen: M6prbp1 antibody was raised against a 14 amino acid synthetic peptide near the internal region of M6prbp1. Application: ELISA, WB, IF

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Catalog Number: (76760-934)

Supplier: Prosci

Description: Anti-USP19 Rabbit Polyclonal Antibody

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Catalog Number: (10070-650)

Supplier: Prosci

Description: Crystallin, alpha B.Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B gene products are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases; a missense mutation cosegregated in a family with a desmin-related myopathy.

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Catalog Number: (76195-318)

Supplier: Prosci

Description: Recognizes a protein of 27kDa, identified as the Bcl-X protein. This mAb shows no cross-reaction with Bcl-2 or Bax protein. Bcl-X has two isoforms, Bcl-XL (long), a 241 amino acid protein which suppresses cell death. And Bcl-XS (short), a 178 amino acid protein lacking a 63 amino acid domain which functions as a dominant inhibitor of Bcl-2. This mAb reacts with both Bcl-XS and Bcl-XL proteins.

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