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Anti-NFIC Rabbit Polyclonal Antibody

Catalog Number: (10111-330)

Supplier: Prosci

Description: Brg- or hBrm-associated factor (BAF) complexes, a chromatin-remodeling complex family of mammalian cells, facilitate transcriptional activity by remodeling nucleosome structure. Brg1 is the core subunit of Brg-associated factor complexes. BAF complexes can interact with NF1/CTF and RNAP II, and this interaction is closely dependent on the activation of gene transcription.

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Anti-PUF60 Rabbit Polyclonal Antibody

Catalog Number: (10108-188)

Supplier: Prosci

Description: PUF60 is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.

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Anti-COX7A2L Rabbit Polyclonal Antibody

Catalog Number: (76011-816)

Supplier: Prosci

Description: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen.

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Anti-ATF2 Goat Polyclonal Antibody

Catalog Number: (10115-318)

Supplier: Prosci

Description: Polyclonal antibody ATF2 Host: Goat Target Species: human immunogen: ATF2 antibody was raised against a 14 amino acid synthetic peptide near the C-Terminus of ATF2. Application: ELISA, WB

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Anti-NOTCH1 Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: mN1A]

Catalog Number: (10765-898)

Supplier: Prosci

Description: The mN1A monoclonal antibody reacts with the intracellular domain of human and mouse Notch1 with high affinity for the activated intracellular form and lower affinity for the full length heterodimeric Notch1 forms. It does not react with Notch2,3, or 4 and does not cross-react with rat thymocytes. The neurogenic locus homolog protein 1 (Notch1) is a trasmembrane receptor that regulates cell fate decisions. It is expressed in CD4-CD8- and CD4-CD8+ thymocytes, and plays a role in the regulation of myelopoiesis and lymphopoiesis.

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Anti-ZBTB10 Rabbit Polyclonal Antibody

Catalog Number: (10111-708)

Supplier: Prosci

Description: ZBTB10 contains 1 BTB (POZ) domain and 2 C2H2-type zinc fingers. ZBTB10 may be involved in transcriptional regulation.

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Anti-SLC2A5 Rabbit Polyclonal Antibody

Catalog Number: (10108-736)

Supplier: Prosci

Description: SLC2A5 is a cytochalasin B-sensitive carrier. It seems to function primarily as a fructose transporter.

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Anti-RAB40B Rabbit Polyclonal Antibody

Catalog Number: (10103-920)

Supplier: Prosci

Description: RAB40B has similarity to a yeast protein which suggests a role of the gene product in regulating secretory vesicles.The protein encoded by this gene has similarity to a yeast protein which suggests a role of the gene product in regulating secretory vesicles.

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