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Product Image-10814-062

Anti-FADD Rabbit Polyclonal Antibody

Catalog Number: (10814-062)
Supplier: Prosci
Description: The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
Product Image-89420-134

Human RUNX1 Peptide (16 aa in the Center)

Catalog Number: (89420-134)
Supplier: Prosci
Description: RUNX1 peptide is used for blocking the activity of RUNX1 antibody.
Image Unavailable-76195-564

Anti-KRT19 Mouse Monoclonal Antibody [clone: A53-B/A2.26]

Catalog Number: (76195-564)
Supplier: Prosci
Description: This antibody is specific to the rod domain of human Cytokeratin 19 (CK19), a polypeptide of 40kDa. Its epitope maps between amino acid 312-335. Cytokeratin 19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Cytokeratin 19 antibody reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Cytokeratin 19 antibody is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.
Product Image-10750-966

Anti-SIRT7 Chicken Polyclonal Antibody

Catalog Number: (10750-966)
Supplier: Prosci
Description: SIRT7 Antibody: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT7 is a nucleolar protein that positively regulates RNA polymerase I transcription and has been postulated to enable cells to sustain critical functions by inhibiting cell growth under severe stress conditions.
Image Unavailable-10764-390

Anti-CD4 Rat Monoclonal Antibody (PerCP (Peridinin-Chlorophyll Protein Complex)-Cy5®.5) [clone: GK1.5]

Catalog Number: (10764-390)
Supplier: Prosci
Description: The GK1.5 monoclonal antibody specifically binds with the mouse CD4 molecule, also known as L3T4, a 55 kDa differentiation antigen which binds to the MHC class II. CD4 is expressed on most thymocytes, a subpopulation of mature T lymphocytes, dendritic cells, pluripotent hematopoietic stem cells, B cell precursors, and lymphoid precursors inside the thymus. It is also expressed on the mouse egg cell membrane, enhancing adhesion to MHC class II bearing sperm. By interaction with MHC class II on the surface of APC, CD4 initiates the development of T lymphocytes and helps the optimum functioning of mature T lymphocytes. The binding of the GK1.5 antibody blocks the binding of the Anti-Mouse CD4 RM4-5 antibody.
Image Unavailable-10765-522

Anti-Fcgr3 Rat Monoclonal Antibody [clone: 2.4G2]

Catalog Number: (10765-522)
Supplier: Prosci
Description: The 2.4G2 monoclonal antibody specifically reacts with an epitope on the extracellular domain of the mouse CD16 (Fc gamma III) and CD 32 (Fc gamma II). CD16 and CD32 are low affinity receptors for the IgG Fc domain and are expressed by B lymphocytes, NK cells, kupffer cells, mast cells, monocytes, macrophages, granulocytes, immature thymocytes, neutrophils, and some activated mature T cells.The 2.4G2 antibody blocks the binding of immunoglobulins to CD16 and CD32, and possibly to Fc gamma I receptor.
Product Image-10068-180

Anti-LIPE Chicken Polyclonal Antibody

Catalog Number: (10068-180)
Supplier: Prosci
Description: Polyclonal, Host: Chicken, Species Reactivity: Mouse, Immunogen: Mouse HSL peptide, Tested Applications: Western blot
Product Image-10102-030

Anti-ZFP36L1 Rabbit Polyclonal Antibody

Catalog Number: (10102-030)
Supplier: Prosci
Description: ZFP36L1 is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors.
Product Image-89419-666

Human BAP3 Peptide (12 aa near N-terminus)

Catalog Number: (89419-666)
Supplier: Prosci
Description: BAP3 peptide is used for blocking the activity of BAP3 antibody.
Product Image-10068-702

Anti-CDK2 Rabbit Polyclonal Antibody

Catalog Number: (10068-702)
Supplier: Prosci
Description: Involved in the control of the cell cycle. Interacts with cyclins A, B1, B3, D, or E. Activity of CDK2 is maximal during S phase and G2.
Product Image-76010-230

Anti-RPS6KL1 Rabbit Polyclonal Antibody

Catalog Number: (76010-230)
Supplier: Prosci
Description: For WB starting dilution is: 1:1000
Product Image-76010-506

Anti-RAB12 Rabbit Polyclonal Antibody

Catalog Number: (76010-506)
Supplier: Prosci
Description: For WB starting dilution is: 1:1000
Product Image-76009-798

Anti-C21orf2 Rabbit Polyclonal Antibody

Catalog Number: (76009-798)
Supplier: Prosci
Description: For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50
Product Image-76011-424

Anti-CCDC153 Rabbit Polyclonal Antibody

Catalog Number: (76011-424)
Supplier: Prosci
Description: The function of CCDC153 remains unknown.
Image Unavailable-76760-666

Anti-PABPC5 Rabbit Polyclonal Antibody

Catalog Number: (76760-666)
Supplier: Prosci
Description: Anti-PABPC5 Rabbit Polyclonal Antibody
Image Unavailable-77127-174

Human Recombinant CD40/TNFRSF5 Protein (from HEK293 cells)

Catalog Number: (77127-174)
Supplier: Prosci
Description: Human Recombinant CD40/TNFRSF5 Protein (from HEK293 cells)
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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