You Searched For: PROSCI INCORPORATED

Catalog Number: (77128-338)

Supplier: Prosci

Description: Anti-Klra6 Mouse Monoclonal Antibody [clone: [HBF-719]] (Biotinylated)

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Catalog Number: (10114-060)

Supplier: Prosci

Description: Polyclonal, Host: Goat, Species Reactivity: Human, Immunogen: CNN2 antibody was raised against a 15 amino acid synthetic peptide near the internal region (near C-Terminus) of CNN2 (near C-Terminus), Tested Applications: ELISA, WB

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Catalog Number: (10750-904)

Supplier: Prosci

Description: FAM82A1 Antibody: The human protein FAM82A1, also known as regulator of microtubule dynamics 2 (RMD2), was one of three proteins identified as related to a family of microtubule-associated proteins in C. elegans. FAM82A1 contains multiple coiled-coil domains and localize to the spindle microtubules and spindle poles during cell division. During interphase, RMD2 localizes to the cytoplasm with protein observed in the microtubule lattice and perinuclear region.

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Catalog Number: (89418-566)

Supplier: Prosci

Description: BACE2 peptide is used for blocking the activity of BACE2 antibody.

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Catalog Number: (76009-038)

Supplier: Prosci

Description: This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.

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Catalog Number: (76012-434)

Supplier: Prosci

Description: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

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Catalog Number: (10097-974)

Supplier: Prosci

Description: Polyclonal, Host: Rabbit, Species reacivity: Human, Immunogen: Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant Human soluble, Tested application: ELISA, WB

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Catalog Number: (10072-720)

Supplier: Prosci

Description: The FGF family plays central roles during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-19, a member of the FGF family, is a high affinity heparin dependent ligand for FGFR4. FGF-19 is expressed during the brain development and embryogenesis. Recombinant human FGF-19 is a 21.8 kDa protein containing 195 amino acid residues.

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Catalog Number: (75790-046)

Supplier: Prosci

Description: Hepatoma-Derived Growth Factor-Related Protein 3 (HDGFRP3) belongs to the HDGF family. HDGFRP3 can be found in testis, heart, spinal cord and brain. HDGFRP3 localizes to the nucleus and contains one PWWP domain. HDGFRP3 enhances DNA synthesis and may have a role in cell proliferation.

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Catalog Number: (75790-176)

Supplier: Prosci

Description: Protein Disulfide-Isomerase A4 (PDIA4) is an endoplasmic reticulum luminal protein that belongs to the protein disulfide isomerase family

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Catalog Number: (10797-156)

Supplier: Prosci

Description: T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.

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Catalog Number: (10072-682)

Supplier: Prosci

Description: Epiregulin is an EGF related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not ErbB2 or ErbB3. It is expressed mainly in the placenta and peripheral blood leukocytes and in certain carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. It also inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence. Recombinant human Epiregulin is a 5.6 kDa monomeric protein, containing 50 amino residues, which corresponds to the mature secreted Epiregulin sequence.

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Catalog Number: (75793-602)

Supplier: Prosci

Description: Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30kDa human IL33 is converted by CASP1 to a 18kDa protein. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1 (MAPK3)/ERK2 (MAPK1), p38 (MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.

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Catalog Number: (10112-414)

Supplier: Prosci

Description: Polyclonal, Host: Goat, Species: Human, Immunogen: APBA1 antibody was raised against a 14 amino acid synthetic peptide near the internal region of APBA1, Application: ELISA, WB

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Catalog Number: (10075-492)

Supplier: Prosci

Description: The Ras pathway is a critical signal transduction cascade involved in regulating cellular proliferation, differentiation, survival, and oncogenic transformation. Members of the Raf serine/threonine kinase family are key intermediates in this cascade, functioning to relay signals from activated Ras to the downstream protein kinases MEK and ERK (Marshall, 1996). Previous studies have shown that phosphorylation is required for Raf-1 activation (Dhillon and Kolch, 2002; Chong et al., 2003). Recent work has demonstrated that phosphorylation also regulates the downregulation of Raf (Dougherty et al., 2005) with two sites participating: Ser301 and Ser642.

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Catalog Number: (10750-460)

Supplier: Prosci

Description: OTUD4 Antibody: OTUD4, also known as HIV-1 induced protein HIN-1, is a member of the OTU (ovarian tumor) domain containing cysteine protease superfamily, in which the OUT domain generally confers deubiquitinase activity. At least three isoforms of OTUD4 are known to exist, and the smallest of these isoforms are only expressed in HIV-1-infected cells (provided by RefSeq).

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