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Description: Polyclonal, Host: Rabbit, Species reacivity: human, Immunogen: Produced from sera of goats pre-immunized with highly pure (>98%) recombinant hSDF-1 beta (Human SDF-1 beta), Tested application: ELISA, WB
Catalog Number: 10097-616
Supplier: Prosci


Description: This antibody recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi’s sarcoma, but shows low specificity.
Catalog Number: 76195-456
Supplier: Prosci


Description: PD-L1 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC) (1). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC (2). PD-1 can bind two different but related ligands, PD-L1 and PD-L2. PD-L1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells (3). This suggests that PD-L1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allografts. PD-L1 also functions as an immune checkpoint protein, and multiple anti-PD-L1 antibodies are currently in phase II and III clinical trials, with one antibody already approved for the treatment of cancer (4).
Catalog Number: 76163-568
Supplier: Prosci


Description: Polyclonal, Host: Goat, Species reacivity: Mouse, Immunogen: Produced from sera of goats pre-immunized with highly pure (>98%) recombinant murine IGF-I, Tested application: ELISA, WB
Catalog Number: 10097-834
Supplier: Prosci


Description: JHDM1a/FBXL11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box),which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 6 highly degenerated leucine-rich repeats.
Catalog Number: 76009-432
Supplier: Prosci


Description: Anti-ANXA2 Rabbit Polyclonal Antibody
Catalog Number: 76756-106
Supplier: Prosci


Description: OCAM Peptide
Catalog Number: 77129-522
Supplier: Prosci


Description: Anti-CX3CR1 Goat Polyclonal Antibody
Catalog Number: 77119-438
Supplier: Prosci


Description: IRAK2 peptide is used for blocking the activity of IRAK2 antibody.
Catalog Number: 89418-538
Supplier: Prosci


Description: Anti-HOOK1 Rabbit Polyclonal Antibody
Catalog Number: 76749-024
Supplier: Prosci


Description: Lipe peptide is used for blocking activity of lipe antibody.
Catalog Number: 89419-296
Supplier: Prosci


Description: The TMEM181 gene encodes a putative G protein-coupled receptor expressed on the cell surface (Carette et al., 2009 [PubMed 19965467]; Wollscheid et al., 2009 [PubMed 19349973]).
Catalog Number: 76010-828
Supplier: Prosci


Description: The protein encoded by this gene localizes to the inner mitochondrial membrane and catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate, using FAD as a cofactor. Along with GDP1, the encoded protein constitutes the glycerol phosphate shuttle, which reoxidizes NADH formed during glycolysis. Two transcript variants encoding the same protein have been found for this gene.
Catalog Number: 76010-894
Supplier: Prosci


Description: CTRP2 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Of the CTRPs, CTRP2 is most similar structurally and functionally to adiponectin. Recombinant CTRP2 rapidly activated AMPK and MAPK in cultured C2C12 cells, leading to increased glycogen accumulation and fatty acid oxidation.
Catalog Number: 89415-866
Supplier: Prosci


Description: sialin/SLC17A5 Peptide
Catalog Number: 77130-496
Supplier: Prosci


Description: Anti-DIAPH1 Rabbit Polyclonal Antibody
Catalog Number: 76758-576
Supplier: Prosci


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