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Catalog Number: (10748-246)
Supplier: Prosci
Description: DR3 Antibody: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel cell death receptor was recently identified by several groups independently and designated DR3, Wsl-1, Apo-3, TRAMP and LARD1-5. The ligand for this novel death receptor has been defined as TWEAK, also termed Apo3L. DR3 is highly expressed in the tissues enriched in lymphocytes including PBL, thymus and spleen. Like TNFR1, DR3 induces apoptosis and NF-kappa B activation.


Catalog Number: (77120-136)
Supplier: Prosci
Description: NEFM Peptide


Catalog Number: (10764-518)
Supplier: Prosci
Description: CD54 Antibody, monoclonal, Host: Mouse, Species reactivity: Human, Isotype: IgG1, Clone: 15.2, Applications: Fluorescence-activated cell sorting, Func, Immunohistochemistry, western blotting


Catalog Number: (77123-512)
Supplier: Prosci
Description: SH2D4A Peptide


Catalog Number: (10100-358)
Supplier: Prosci
Description: GALE is an UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified.


Catalog Number: (10766-458)
Supplier: Prosci
Description: Rat Monoclonal CD45 Antibody [30-F11] (APC), Isotype: IgG2b, Kappa, Species: Mouse, Application: Facs


Catalog Number: (77127-618)
Supplier: Prosci
Description: SNX5 Peptide


Catalog Number: (77123-590)
Supplier: Prosci
Description: Anti-CD44 Mouse Monoclonal Antibody [clone: [F10-44-2]] (APC (Allophycocyanin))


Catalog Number: (76753-168)
Supplier: Prosci
Description: Anti-HDAC4 Rabbit Polyclonal Antibody


Catalog Number: (76756-594)
Supplier: Prosci
Description: Anti-rhuMAb Recombinant Antibody


Catalog Number: (10751-112)
Supplier: Prosci
Description: PLAC3 Antibody: PLAC3 (placenta-specific protein 3), also known as PAPP-A2, is a metalloproteinase that cleaves the insulin-like growth factor-binding protein (IGFBP)-5 in a IGF-independent fashion. It has been suggested that the cleavage of IGFBP-5 and to a lesser extent IGFBP-3 produced in the maternal decidua promotes feto-placental growth. Recent studies have shown elevated levels of PLAC3 in hypertensive disorders of pregnancy including preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.


Catalog Number: (76011-754)
Supplier: Prosci
Description: GRIN3B is a NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. It is mediated by glycine.


Catalog Number: (76762-398)
Supplier: Prosci
Description: Anti-LFB-R603 Recombinant Antibody


Catalog Number: (89418-492)
Supplier: Prosci
Description: IKK alpha peptide is used for blocking the activity of IKK alpha antibody.


Catalog Number: (10105-396)
Supplier: Prosci
Description: HR is a protein whose function has been linked to hair growth. A similar protein in rat functions as a transcriptional corepressor for thyroid hormone and interacts with histone deacetylases. Mutations in this gene have been documented in cases of autosomal recessive congenital alopecia and atrichia with papular lesions.This gene encodes a protein whose function has been linked to hair growth. A similar protein in rat functions as a transcriptional corepressor for thyroid hormone and interacts with histone deacetylases. Mutations in this gene have been documented in cases of autosomal recessive congenital alopecia and atrichia with papular lesions. Two transcript variants encoding different isoforms have been found for this gene.


Catalog Number: (76748-742)
Supplier: Prosci
Description: Anti-OVOL1 Rabbit Polyclonal Antibody


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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