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Catalog Number: (10101-688)
Supplier: Prosci
Description: This gene is part of a gene cluster on chromosome Xp11.23. PHF16 contains a zinc finger motif often found in transcriptional regulators, however, its exact function is not known.This gene is part of a gene cluster on chromosome Xp11.23. The encoded protein contains a zinc finger motif often found in transcriptional regulators, however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding the same protein.


Catalog Number: (10796-996)
Supplier: Prosci
Description: ApoA1 is also known as apolipoprotein A-I, ApoA-I , and is the major protein component of high density lipoprotein (HDL) in plasma. It has a specific role in lipid metabolism. Chylomicrons secreted from the intestinal enterocyte also contain ApoA1 but it is quickly transferred to HDL in the bloodstream. The protein promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterol acyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. ApoA-I was also isolated as a prostacyclin (PGI2) stabilizing factor, and thus may have an anticlotting effect. Defects in the gene encoding it are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. In addition, it has been shown that ApoA1 is implicated in the anti-endotoxin function of HDL via interaction with lipopolysaccharide or endotoxin.


Catalog Number: (76009-590)
Supplier: Prosci
Description: BHLHE40 encodes a basic helix-loop-helix protein expressed in various tissues. Expression in the chondrocytes is responsive to the addition of Bt2cAMP. The encoded protein is believed to be involved in the control of cell differentiation.


Catalog Number: (76629-994)
Supplier: Prosci
Description: Anti-HLA Class II Recombinant Antibody [Clone: F3.3]


Catalog Number: (10109-626)
Supplier: Prosci
Description: CRISPLD2 is a novel NSCLP candidate gene.


Catalog Number: (76755-372)
Supplier: Prosci
Description: Anti-ABCB7 Rabbit Polyclonal Antibody


Catalog Number: (76009-634)
Supplier: Prosci
Description: HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.


Catalog Number: (89417-004)
Supplier: Prosci
Description: AP2M1 Antibody: The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP2M1 are known to exist.


Catalog Number: (10798-310)
Supplier: Prosci
Description: Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) is also known as ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, CD antigen CD134, OX40. OX40 / TNFRSF4 contains four TNFR-Cys repeats. TNFRSF4 is receptor for TNFSF4 / OX40L / GP34 and can interacts with TRAF2, TRAF3 and TRAF5.


Catalog Number: (77130-564)
Supplier: Prosci
Description: Anti-fibrinogen alpha chain Goat Polyclonal Antibody


Catalog Number: (77124-904)
Supplier: Prosci
Description: CRKL Peptide


Catalog Number: (10114-710)
Supplier: Prosci
Description: Polyclonal, Host: Goat; Target Species: Human; Immunogen: SPINT2 antibody was raised against a 12 amino acid synthetic peptide near the internal region of SPINT2; Applications: ELISA,Western blotting


Catalog Number: (10764-928)
Supplier: Prosci
Description: The BNI3 monoclonal antibody specifically reacts with human CD152, the Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4). CTLA-4 is expressed on activated CD28+ T cells, and binds the B7 family members B7-1 (CD80) and B7-2 (CD86). The structure of CTLA-4 is similar to the structure of CD28, but the two molecules seem to have opposite roles on the T lymphocytes. CTLA-4 inhibits the progression of T cell activation, while CD28 stimulates it. This result explains the stimulating role that the immobilization of BNI3 plays on the T lymphocytes proliferation induced by CD28.


Catalog Number: (76749-856)
Supplier: Prosci
Description: Anti-KIFAP3 Rabbit Polyclonal Antibody


Catalog Number: (10766-578)
Supplier: Prosci
Description: The 156-4H9 monoclonal antibody specifically reacts with human CD48, a GPI-linked glycoprotein in the Ig superfamily. CD48 was previously known as BCM1 in mice, Blast-1 in humans, and OX-45 in rats. Its ligands are CD2 and CD244 and it is expressed on leukocytes to the exclusion of non-hematopoietic cells and its expression increases in B cells upon activation.


Catalog Number: (89419-306)
Supplier: Prosci
Description: PEN2 peptide is used for blocking activity of PEN2 antibody.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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