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Catalog Number: (75789-566)
Supplier: Prosci
Description: Neuroligin-1 is a single-pass type I transmembrane protein which belongs to the type-B Carboxylesterase/Lipase family. Neuroligins are cell-adhesion molecules located at the postsynaptic side of the synapse. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses. Neurexins and Neuroligins are cell adhesion molecules present in excitatory and inhibitory synapses, and they are required for correct neuron network function. These proteins are found at the presynaptic and postsynaptic membranes. Neuroligin-1 is a neuronal cell surface protein which is thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. It seems to play role in formation or maintenance of synaptic junctions. It triggers the de novo formation of presynaptic structures and may be involved in specification of excitatory synapses.


Catalog Number: (10110-114)
Supplier: Prosci
Description: The exact function of LOC390110 remains unknown.


Catalog Number: (89418-624)
Supplier: Prosci
Description: NAK peptide is used for blocking the activity of NAK/TBK1 antibody.


Catalog Number: (10102-702)
Supplier: Prosci
Description: RNF19A contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB.The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported.


Catalog Number: (10101-754)
Supplier: Prosci
Description: SHROOM2 shares significant similarities with the apical protein from Xenopus laevis which is implicated in amiloride-sensitive sodium channel activity. This gene is a strong candidate gene for ocular albinism type 1 syndrome.The protein encoded by this gene shares significant similarities with the apical protein from Xenopus laevis which is implicated in amiloride-sensitive sodium channel activity. This gene is a strong candidate gene for ocular albinism type 1 syndrome.


Catalog Number: (10100-442)
Supplier: Prosci
Description: TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6), yeast Bub2, and CDC16.TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6; MIM 604334), yeast Bub2, and CDC16 (MIM 603461) (White et al., 2000 [PubMed 10965142]).


Catalog Number: (10098-528)
Supplier: Prosci
Description: Polyclonal, Host: Rabbit, Species reacivity: human, Immunogen: Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hHCC-1 (human HCC-1), Tested application: ELISA, WB


Catalog Number: (10069-552)
Supplier: Prosci
Description: Polyclonal, Host: Rabbit, Species Reactivity: Bacteria, Immunogen: Purified spores of B. cereus + B. subtilis, Tested Applications: Western blotting


Catalog Number: (76012-234)
Supplier: Prosci
Description: Zmat2 contains 1 matrin type zinc finger.


Catalog Number: (10115-626)
Supplier: Prosci
Description: Polyclonal antibody ACAP2 Host: Goat Target Species: human immunogen: ACAP2 antibody was raised against a 13 amino acid synthetic peptide near the C-Terminus of ACAP2. Application: ELISA, WB, IHC


Catalog Number: (10069-632)
Supplier: Prosci
Description: Polyclonal, Host: Rabbit, Species Reactivity: Bacteria, Immunogen: Klebsiella pneumoniae, Tested Applications: Western blotting


Catalog Number: (10750-308)
Supplier: Prosci
Description: Spred1 Antibody: The Ras-MAP kinase pathway is essential for the differentiation of neuronal cells and myocytes; it is inhibited by Spred1, a member of the Sprouty family of proteins. Spred1 acts by suppressing the phosphorylation and activation of Raf. The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS).


Catalog Number: (76194-476)
Supplier: Prosci
Description: It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP2 secretion requires the Ras signaling pathway.


Catalog Number: (75791-878)
Supplier: Prosci
Description: Aminoglycoside 3'-phosphotransferase (APH(3')), also known as aminoglycoside kinase, is an aminoglycoside-modifying enzyme and widely presented in resistant bacteria


Catalog Number: (10062-356)
Supplier: Prosci
Description: 19 amino acids near the center of Heartland Virus Glycoprotein 2.


Catalog Number: (10098-184)
Supplier: Prosci
Description: Polyclonal, Host: Goat, Species reacivity: Human, Immunogen: Produced from sera of goats pre-immunized with highly pure (>98%) recombinant hLD78 beta (human LD78 beta), Tested application: ELISA, WB


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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