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Catalog Number: (10109-160)
Supplier: Prosci
Description: RELB neither associates with DNA nor with RELA/p65 or REL. It stimulates promoter activity in the presence of NFKB2/p49.


Catalog Number: (10107-572)
Supplier: Prosci
Description: The function of JMJD4 remains unkonwn.


Catalog Number: (10114-904)
Supplier: Prosci
Description: Polyclonal, Host: Goat; Immunogen: LAX1 antibody was raised against a 14 amino acid synthetic peptide near the internal region of LAX1; Applications: ELISA


Catalog Number: (76010-884)
Supplier: Prosci
Description: This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq].


Catalog Number: (10766-504)
Supplier: Prosci
Description: The OKT8 monoclonal antibody specifically reacts with human CD8alpha molecule, a type I transmembrane glycoprotein of 32-34 kDa. CD8 alpha is a member of the Ig superfamily, expressed as a homodimer (CD8 alpha alpha) or as a heterodimer (CD8 alpha beta). CD8+ alpha beta T lymphocytes express both CD8 alpha alpha and CD8 alpha beta, while some T lymphocytes and the natural killer cells express only the homodimers. CD8 binds to MHC class I and influences the development and the activation of T lymphocytes. OKT8, RPA-T8, and HIT8a antibodies do not compete with each other for binding to peripheral leukocytes, meaning that that they do not recognize the same epitoPEor block each other by steric hindrance.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.


Catalog Number: (89420-894)
Supplier: Prosci
Description: LRRTM3 peptide is used for blocking the activity of LRRTM3 antibody.


Catalog Number: (10764-740)
Supplier: Prosci
Description: The 2.43 monoclonal antibody specifically reacts with mouse CD8 antigen. CD8a (the alpha chains) form heterodimers with CD8b (the beta chains) or homodimers (alpha-alpha), which occur as receptors on the surface of the majority of thymocytes. A subpopulation of mature T lymphocytes expresses the CD8 alpha beta (alpha beta TCR T cells), and a subpopulation of intestinal intraepithelial lymphocytes and dendritic cells express CD8a without CD8b. CD8 interacts with the mouse major histocompatibility complex class I (MHC class I) molecules on antigen-presenting cells or epithelial cells.


Catalog Number: (10071-358)
Supplier: Prosci
Description: Polyclonal antibody CCNI Host: Chicken Species reactivity: Human, Mouse, Rat immunogen: 211-377 Tested application: WB


Catalog Number: (75789-572)
Supplier: Prosci
Description: Oncostatin-M-Specific Receptor Subunit beta (OSMR beta ) is a 150 - 180 kDa member of the IL-6 receptor family. OSMR beta associates with gp130 to form the type II OSM receptor, the receptor is responsive to OSM. Gp130 subunit is shared by other IL-6 family cytokine receptors, and OSMR beta associates with gp130-like receptor (GPL) to form a receptor complex responsive to IL-31. The human OSMR beta cDNA encodes a 979 amino acid (aa) precursor, the precursor includes a 27 aa signal sequence, a 712 aa extracellular domain (ECD), a 22 aatransmembrane segment, and a 218 aa cytoplasmic domain. The ECD contains one partial and one complete hematopoietin domain, an Ig-like domain, and three Fibronectin type-III domains.


Catalog Number: (10116-188)
Supplier: Prosci
Description: Polyclonal antibody KLF16 Host: Goat Target Species: human immunogen: KLF16 antibody was raised against a 14 amino acid synthetic peptide near the C-Terminus of KLF16. Application: ELISA, WB, IHC


Catalog Number: (10116-162)
Supplier: Prosci
Description: Polyclonal antibody JIP3 Host: Goat Target Species: mouse immunogen: JIP3 antibody was raised against a 12 amino acid synthetic peptide near the N-Terminus of JIP3 Application: ELISA


Catalog Number: (10106-982)
Supplier: Prosci
Description: DR1 is a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. DR1 is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. DR1 contains a histone fold motif


Catalog Number: (10071-552)
Supplier: Prosci
Description: Monoclonal antibody Hepatitis B Virus Host: Mouse Clone no: 1894 Species reactivity: Virus isotype: IgG1 Tested application: ELISA


Catalog Number: (75794-192)
Supplier: Prosci
Description: CCL5, also known as RANTES (Regulated upon Activation Normal T cell Expressed and Secreted), is an 8kDa β-chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract and activate leukocytes. Human and mouse RANTES exhibit cross-species activity on human and mouse cells. CCL5 is secreted by many cell types at inflammatory sites and it exerts a wide range of activities through the receptors CCR1, CCR3, CCR4 and CCR5. In humans, CCR5 binding to CCL5 inhibits the infectivity of R5 (M-tropic) but not X4 (T-tropic) strains of HIV-1. The deposition of CCL5 on activated vascular endothelial cells is crucial for monocyte adhesion to damaged vasculature, but CCL5 oligomerization is not required for the extravasation of adherent leukocytes. CCL5 is upregulated in breast cancer and promotes tumor progression through the attraction of proinflammatory macrophages in addition to its actions on tumor cells, stromal cells and the vasculature.


Catalog Number: (75794-156)
Supplier: Prosci
Description: GCN5 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. It has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. It regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. GCN5 is a component of the Ada Two-A containing (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4.


Catalog Number: (76760-392)
Supplier: Prosci
Description: Anti-SHR-1314 Recombinant Antibody


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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