You Searched For: PROSCI INCORPORATED

Catalog Number: (10749-040)

Supplier: Prosci

Description: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. ATG4B, also known as AUTL1, is one of four mammalian orthologs of the yeast ATG4 protein; all four are cysteine proteases. ATG4 is required for ATG8 conjugation to phosphatidylethanolamine on autophagosomal membranes. In mammals, each ATG4 homolog shows a selective preference for the ATG8 homologs. ATG4B has been found to be a novel protective protein in inflammatory colitis.

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Catalog Number: (76761-348)

Supplier: Prosci

Description: Anti-FOS Rabbit Polyclonal Antibody

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Catalog Number: (77131-550)

Supplier: Prosci

Description: GSTP1 Peptide

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Catalog Number: (77122-038)

Supplier: Prosci

Description: Anti-CD14 Mouse Monoclonal Antibody [clone: [UCHM-1]] (PE (Phycoerythrin))

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Catalog Number: (76764-460)

Supplier: Prosci

Description: Anti-EIF4B Rabbit Polyclonal Antibody

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Catalog Number: (10751-642)

Supplier: Prosci

Description: DBX2 Antibody: DBX2 is a member of the developing brain homeobox (DBX) protein family, but while the related protein DBX1 is expressed in various regions of the developing brain, DBX2 shows a more restricted pattern of expression in the brain, and is also expressed in some mesenchymal cells such as limb buds and tooth germs. It is thought that DBX1 and DBX2 promote the development of a subset of interneurons, some of which help mediate left-right coordination of locomotor activity. In Xenopus, DBX2 is involved in primary neurogenesis and early neural plate patterning, and is thought to act as a cross-repressive partner of NKX6-2 in the patterning of the ventral neural tube.

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Catalog Number: (89419-364)

Supplier: Prosci

Description: TIGAR peptide is used for blocking the activity of TIGAR antibody.

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Catalog Number: (10765-116)

Supplier: Prosci

Description: The 29A1.4 antibody specifically reacts with CD335 (NKp46), a 46kDA natural cytotoxicity receptor family molecule. It is expressed in only NK and a rare subset of NK-like T cells, not including the CD1d-restricted NKT division. CD335 is active during NK lysis of pathogen-infected and tumor cells.The 29A1.4 in vitro activates NK cells, but does not deplete NK cells in vivo.

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Catalog Number: (89419-410)

Supplier: Prosci

Description: ORAI2 peptide is used for blocking the activity of ORAI2 antibody.

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Catalog Number: (89417-808)

Supplier: Prosci

Description: SLAMF2 Antibody: The signaling lymphocyte-activation molecule family member 2 (SLAMF2), also known as CD48, is a GPI-anchored protein that exists as both a soluble and membrane-associated form and is expressed in almost all leukocyte populations particularly in mitogen-stimulated human lymphocytes. SLAMF2 is a high-affinity ligand for SLAMF4, also known as 2B4, as well as a low-affinity ligand for CD2, and can thus can stimulate cells expressing these receptors. It has been shown to be an IL-3-induced activating receptor on eosinophils and is likely to be involved in promoting allergic inflammation. SLAMF2 is also thought to be involved in the IL-18/IL-18R signaling cascade in T and natural killer cells to produce interferon-gamma.

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Catalog Number: (89420-570)

Supplier: Prosci

Description: APC3 peptide is used for blocking the activity of APC3 antibody.

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Catalog Number: (89417-934)

Supplier: Prosci

Description: UHRF1BP1 Antibody: The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1 (UHRF1BP1), also known as ICBP90, is a transcription and cell cycle regulator. It specifically binds to the histone H3 N-terminal tail when methylated on K9 by two functional domains, a PHD finger that defines the binding specificity and an SRA (SET- and RING-associated) domain that promotes binding activity. UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells.

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Catalog Number: (75792-902)

Supplier: Prosci

Description: TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.

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Catalog Number: (10072-288)

Supplier: Prosci

Description: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules.

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Catalog Number: (75790-438)

Supplier: Prosci

Description: Cathepsin E is encoded by the ctse gene, exists in the homodimer forms, belongs to the peptidase A1 family. Cathepsin E high expressed in the stomach, clara cells and alveolar macrophages of lung, brain microglia, spleen and activated B-lymphocytes. Cathepsin E may involve in the processing of antigenic peptides during MHC class II-mediated antigen presentation, play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.

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Catalog Number: (10113-188)

Supplier: Prosci

Description: Polyclonal, Host: Goat, Immunogen: ABCA4 antibody was raised against a 14 amino acid synthetic peptide near the C-Terminus of ABCA4, Tested Applications: ELISA

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