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Product Image-89420-904

Human SLAMF9 Peptide

Catalog Number: (89420-904)
Supplier: Prosci
Description: SLAMF9 peptide is used for blocking the activity of SLAMF9 antibody.
Product Image-89419-652

Human SIRT2 Peptide (17 aa near N-terminus)

Catalog Number: (89419-652)
Supplier: Prosci
Description: SIRT2 peptide is used for blocking the activity of SIRT2 antibody.
Product Image-10813-844

Anti-ADRB2 Rabbit Polyclonal Antibody

Catalog Number: (10813-844)
Supplier: Prosci
Description: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
Product Image-10105-034

Anti-NFKB2 Rabbit Polyclonal Antibody

Catalog Number: (10105-034)
Supplier: Prosci
Description: NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.
Image Unavailable-10764-318

Anti-CD3E Mouse Monoclonal Antibody (PE (Phycoerythrin)-Cy7®) [clone: UCHT1]

Catalog Number: (10764-318)
Supplier: Prosci
Description: The UCHT1 monoclonal antibody specifically reacts with the epsilon chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains gamma, delta, and epsilon chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction. Unlike HIT3a, another specific antibody of CD3, the UCHT1 antibody can stain both the surface and intracellular CD3 epsilon. The immobilized UCHT1 can cross-link with the TCR complex, enhancing cellular activation and proliferation.
Product Image-10070-234

Anti-RPS6KA1 Rabbit Polyclonal Antibody

Catalog Number: (10070-234)
Supplier: Prosci
Description: Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.
Product Image-10797-382

Recombinant Gp120 (from HEK293 cells)

Catalog Number: (10797-382)
Supplier: Prosci
Description: Human Immunodeficiency Virus (HIV) can be divided into two major types, HIV type 1 (HIV-1) and HIV type 2 (HIV-2). HIV-1 is related to viruses found in chimpanzees and gorillas living in western Africa. HIV-2 is related to viruses found in sooty mangabeys. HIV-1 viruses may be further divided into groups. The HIV-1 group M viruses predominate and are responsible for the AIDS pandemic. Some of the HIV-1 group M subtypes are known to be more virulent or are resistant to different medications. HIV-2 viruses are thought to be less virulent and transmissible than HIV-1 M group viruses.
Envelope glycoprotein GP120 (or gp120) is the name of the glycoprotein which forms the spikes sticking out of a HIV virus particle. gp120 is essential for virus entry into cells as it plays a vital role in seeking out specific cell surface receptors for entry. Three gp120s, bound as heterodimers to a transmembrane glycoprotein, gp41, are thought to combine in a trimer to form the envelope spike, which is involved in virus-cell attachment. One half of the molecular weight of gp120 is due to the carbohydrate side chains (the "glyco-" in "glycoprotein"). These are sugar residues which form something almost like a sugar "dome" over the gp120 spikes. This dome prevents gp120 from being recognised by the human immune response. As the HIV virus and the human CD4 cell come together, the gp120 binding site "snaps open" at the last minute.The glycoprotein gp120 is anchored to the viral membrane, or envelope, via non-covalent bonds with the transmembrane glycoprotein, gp41. It is involved in entry into cells by binding to CD4 receptors, particularly helper T-cells. Binding to CD4 is mainly electrostatic although there are van der Waals interactions and hydrogen bonds.
Image Unavailable-75790-980

Human Recombinant Calreticulin 2 (from E. coli)

Catalog Number: (75790-980)
Supplier: Prosci
Description: Calreticulin-3 belongs to the calreticulin family, members of which are calcium binding chaperones localized mainly in the endoplasmic reticulum. It can be divided into a N-terminal globular domain, a proline-rich P-domain forming an elongated arm-like structure and a C-terminal acidic domain. During spermatogenesis process, Calreticulin-3 may act as a lectin-independent chaperone for specific client proteins such as ADAM3. Defects in CALR3 are the cause of familial hypertrophic cardiomyopathy type 19 (CMH19), it is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain.
Product Image-10071-440

Anti-GATA1 Rabbit Polyclonal Antibody

Catalog Number: (10071-440)
Supplier: Prosci
Description: GATA1 encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.
Image Unavailable-75793-988

Human Recombinant LAG3 (from CHO cells)

Catalog Number: (75793-988)
Supplier: Prosci
Description: Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
Image Unavailable-76749-786

Anti-ADRA1B Rabbit Polyclonal Antibody

Catalog Number: (76749-786)
Supplier: Prosci
Description: Anti-ADRA1B Rabbit Polyclonal Antibody
Image Unavailable-76757-638

Anti-ALG9 Rabbit Polyclonal Antibody

Catalog Number: (76757-638)
Supplier: Prosci
Description: Anti-ALG9 Rabbit Polyclonal Antibody
Image Unavailable-76759-602

Anti-PRKAA1 Rabbit Polyclonal Antibody

Catalog Number: (76759-602)
Supplier: Prosci
Description: Anti-PRKAA1 Rabbit Polyclonal Antibody
Image Unavailable-77132-558

BIF-1 Peptide

Catalog Number: (77132-558)
Supplier: Prosci
Description: BIF-1 Peptide
Image Unavailable-77121-882

Anti-XKR8 Rabbit Polyclonal Antibody

Catalog Number: (77121-882)
Supplier: Prosci
Description: Anti-XKR8 Rabbit Polyclonal Antibody
Image Unavailable-77130-268

Vinculin Peptide

Catalog Number: (77130-268)
Supplier: Prosci
Description: Vinculin Peptide
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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* Please note if your account is within the State of California two of these pieces of identification will be required.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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