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Catalog Number: (10105-680)
Supplier: Prosci
Description: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This protein, a member of the claudin family, is an integral membrane protein and a component of tight junction strands.


Catalog Number: (10750-506)
Supplier: Prosci
Description: Siglec11 Antibody: Siglecs are sialic acid-binding lectins of the immunoglobulin superfamily that are mainly expressed in cells of the hematopoietic system. Siglec11 is unlike other siglecs in that it binds specifically to alpha2-8-linked sialic acids and is not found in peripheral blood leukocytes but instead on macrophages of various tissues. Siglec11 is highly homologous to Siglec10 over their extracellular domain but not over their cytoplasmic domain, suggesting that Siglec11 arose through gene duplication followed by a recombination event involving another ancestral siglec gene. Following treatment of Siglec11-transfected cells with pervanadate, Siglec11 becomes tyrosine-phosphorylated and strongly associates with SHP-1 and SHP-2. At least five isoforms of Siglec11 are known to exist. Siglec11 antibody will not cross-react with Siglec10.


Catalog Number: (10097-826)
Supplier: Prosci
Description: IFN gamma receptor beta is part of the receptor for interferon gamma. This class II cytokine receptor pairs with CDw119 to form the IFN gamma receptor and is an integral part of the IFN gamma signal transduction pathway. CDw119 serves as the IFN gamma binding chain and associates with the IFN gamma beta chain which is required for receptor signaling. The extracellular portion of both the IFN gamma receptor alpha and beta chains must be species matched. The IFN gamma receptor beta chain is expressed on T and B cells, NK cells, monocytes/ macrophages, and fibroblasts. Binding of IFN gamma induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. It is also likely to interact with GAF. IFN gamma initiates and regulates a variety of immune responses and is required for signal transduction. Contains 2 fibronectin type III domains. Defects in IFN gamma Receptor beta are a cause of mendelian susceptibility to mycobacterial disease (MSMD), a rare condition that confers predisposition to illness caused by several mycobacteria strains


Catalog Number: (76750-218)
Supplier: Prosci
Description: Anti-METTL7B Rabbit Polyclonal Antibody


Catalog Number: (76755-952)
Supplier: Prosci
Description: Anti-Nucleoprotein Rabbit Recombinant Antibody [clone: 85C10]


Catalog Number: (77129-442)
Supplier: Prosci
Description: MAML1 Peptide


Catalog Number: (10117-144)
Supplier: Prosci
Description: Polyclonal; Host: Goat; Species Reactiviy: Human; Immunogen: COL4A3BP antibody was raised against a 16 amino acid synthetic peptide near the internal region of COL4A3BP; Application: ELISA, Western Blot


Catalog Number: (10068-442)
Supplier: Prosci
Description: May associate with CD21. May regulate the release of Ca2+ from intracellular stores.


Catalog Number: (76763-720)
Supplier: Prosci
Description: Anti-J695 Recombinant Antibody


Catalog Number: (76756-238)
Supplier: Prosci
Description: Anti-TXNRD1 Rabbit Polyclonal Antibody


Catalog Number: (76754-998)
Supplier: Prosci
Description: Anti-CPA4 Rabbit Polyclonal Antibody


Catalog Number: (77120-788)
Supplier: Prosci
Description: SARS-CoV-2 (COVID-19) Recombinant NSP9 Protein (from bacteria)


Catalog Number: (77133-550)
Supplier: Prosci
Description: Human Recombinant SARS-CoV-2 (COVID-19) Spike S1 Protein (from HEK293 cells)


Catalog Number: (77134-616)
Supplier: Prosci
Description: AKAP95 Peptide


Catalog Number: (77129-116)
Supplier: Prosci
Description: BOULE Peptide


Catalog Number: (77119-640)
Supplier: Prosci
Description: CCKA Receptor Peptide


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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  • State issued document with your organization's Federal Tax ID Number
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* Please note if your account is within the State of California two of these pieces of identification will be required.
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The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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