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Image Unavailable-77134-282

USP28 Peptide

Catalog Number: (77134-282)
Supplier: Prosci
Description: USP28 Peptide
Product Image-10109-330

Anti-FMO3 Rabbit Polyclonal Antibody

Catalog Number: (10109-330)
Supplier: Prosci
Description: FMO3 is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. It N-oxygenates primary aliphatic alkylamines as well as secondary and tertiary amines. It acts on TMA to produce TMA-N-oxide.
Image Unavailable-76763-384

Anti-PROC Rabbit Polyclonal Antibody

Catalog Number: (76763-384)
Supplier: Prosci
Description: Anti-PROC Rabbit Polyclonal Antibody
Image Unavailable-76752-082

Anti-BCL2 Rabbit Polyclonal Antibody

Catalog Number: (76752-082)
Supplier: Prosci
Description: Anti-BCL2 Rabbit Polyclonal Antibody
Image Unavailable-75790-528

Mouse Recombinant TWEAK Receptor

Catalog Number: (75790-528)
Supplier: Prosci
Description: Tumor necrosis factor receptor superfamily member 12A(Tnfrsf12a) is a single-pass type I membrane protein and contains 1 TNFR-Cys repeat. It is weak inducer of apoptosis in some cell types.It promotes angiogenesis and it is the proliferation of endothelial cells. It may modulate cellular adhesion to matrix proteins.TNFR binds specifically to tumor necrosis factor (TNF) and blocks its interaction with cell surface TNF receptors. TNF is a naturally occurring cytokine that is involved in normal inflammatory and immune responses. It plays an important role in the inflammatory processes of rheumatoid arthritis (RA), polyarticular-course juvenile rheumatoid arthritis (JRA), and ankylosing spondylitis and the resulting joint pathology. In addition, TNF plays a role in the inflammatory process of plaque psoriasis. Elevated levels of TNF are found in involved tissues and fluids of patients with RA, psoriatic arthritis, ankylosing spondylitis (AS), and plaque psoriasis. Two distinct receptors for TNF (TNFRs), a 55 kilodalton protein (p55) and a 75 kilodalton protein (p75), exist naturally as monomeric molecules on cell surfaces and in soluble forms. Biological activity of TNF is dependent upon binding to either cell surface TNFR.
Image Unavailable-76759-050

Anti-3C-like proteinase Rabbit Polyclonal Antibody

Catalog Number: (76759-050)
Supplier: Prosci
Description: Anti-3C-like proteinase Rabbit Polyclonal Antibody
Product Image-10750-302

Anti-ITGA4 Rabbit Polyclonal Antibody

Catalog Number: (10750-302)
Supplier: Prosci
Description: Integrin alpha 4 Antibody: The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains. Alpha4 chain associates with either beta1 or beta7 chain. It has been demonstrated that the putative ligand-binding sites of both integrin alpha4beta1 and alpha4beta7 is located on the alpha4 chain. These ligands included Madcam, VCAM, and fibronectin. Madcam is known as the principal ligand for integrin alpha4beta7. Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.
Image Unavailable-77123-086

TpCN2 Peptide

Catalog Number: (77123-086)
Supplier: Prosci
Description: TpCN2 Peptide
Product Image-10104-458

Anti-PSMD4 Rabbit Polyclonal Antibody

Catalog Number: (10104-458)
Supplier: Prosci
Description: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD4 encodes one of the non-ATPase subunits of the 19S regulator lid. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Product Image-89417-404

Anti-TMEM184B Rabbit Polyclonal Antibody

Catalog Number: (89417-404)
Supplier: Prosci
Description: TMEM184B Antibody: TMEM184B, also known as C22orf5, is a 407 amino acid multi-pass membrane protein and represents a novel gene in the activation of the MAPK signaling pathway. The gene encoding TMEM184B maps to human chromosome 22; mutations in several of the genes in chromosome 22 are involved in the development of autism, schizophrenia, Phelan-McDermid syndrome and Neurofibromatosis type 2, suggesting that TMEM184B may play a role in these syndromes.
Image Unavailable-76757-194

Anti-EPS8 Rabbit Polyclonal Antibody

Catalog Number: (76757-194)
Supplier: Prosci
Description: Anti-EPS8 Rabbit Polyclonal Antibody
Product Image-10106-348

Anti-ZNF551 Rabbit Polyclonal Antibody

Catalog Number: (10106-348)
Supplier: Prosci
Description: Located on chromosome 19, ZNF551 encodes a protein that is part of the zinc finger protein family.
Image Unavailable-76764-772

Anti-TMEM11 Rabbit Polyclonal Antibody

Catalog Number: (76764-772)
Supplier: Prosci
Description: Anti-TMEM11 Rabbit Polyclonal Antibody
Product Image-10751-478

Anti-MS4A6A Rabbit Polyclonal Antibody

Catalog Number: (10751-478)
Supplier: Prosci
Description: MS4A6A Antibody: The MS4A gene family in humans includes CD20 (MS4A1), FcRbeta (MS4A2), Htm4 (MS4A3), and at least 13 other genes encoding membrane proteins, most having characteristic tetraspanning topology and similar intron/exon splice boundaries. All family members display unique expression patterns among hematopoietic cells and non-lymphoid tissues. The function of MS4A6A has been suggested to be involved in signal transduction as a component of a multimeric receptor complex in Alzheimer's disease and cancer.
Image Unavailable-75789-382

Human Recombinant Biglycan (from Cells)

Catalog Number: (75789-382)
Supplier: Prosci
Description: Biglycan is a 200-350 kD proteoglycan consisting of a 45 kD core protein and two chrondroitin/dermatan sulfate glycosaminoglycan chains. Biglycan binds to TGF-ß. It also binds to collagen type I in low ionic strength (less than 3 mM phosphate) buffer. At higher ionic strengths, Biglycan does not bind to collagen type I. It enhances the inhibition effect of TGF-ß on osteoclast proliferation at a concentration of 4-20 mg/ml. It also prevents the attachment of CHO cells to fibronectin, with a 50% inhibition at 17-21 mg/ml.
Product Image-10099-978

Anti-ECHDC2 Rabbit Polyclonal Antibody

Catalog Number: (10099-978)
Supplier: Prosci
Description: ECHDC2 belongs to the enoyl-CoA hydratase/isomerase family. The exact function of ECHDC2 remains unknown.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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