You Searched For: Trace Measurement Limited

Catalog Number: (89281-886)

Supplier: Genetex

Description: Rabbit polyclonal antibody to ZAP70 (phospho Tyr319)

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Catalog Number: (89359-992)

Supplier: Genetex

Description: Brutons tyrosine kinase (Btk) is a member of the Btk/Tec family of cytoplasmic tyrosine kinases. Like other Btk family members, it contains a pleckstrin homology (PH) domain, Src homology SH3 and SH2 domains. Btk plays an important role in B cell development. Activation of B cells by various ligands is accompanied by Btk membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane-located Btk is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinase, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation. The activation of Btk is negatively regulated by PKCbeta through phosphorylation of Btk at Ser180, which results in reduced membrane recruitment, transphosphorylation and subsequent activation. The PKC/Btk inhibitory signal is likely to be a key determinant of the B-cell receptor signaling threshold to maintain optimal Btk activity.

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Catalog Number: (89360-542)

Supplier: Genetex

Description: Pericentrin is probably a conserved integral component of the filamentous matrix of the centrosome involved in the initial establishment of organized microtubule arrays.

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Catalog Number: (89361-534)

Supplier: Genetex

Description: Rabbit polyclonal antibody to Phospholipase C1 gamma (phospho Tyr783)

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Catalog Number: (89285-408)

Supplier: Genetex

Description: Rabbit Polyclonal to ETL

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Catalog Number: (10793-192)

Supplier: Genetex

Description: Mouse monoclonal antibody [7A9] to Cas9

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Catalog Number: (89310-734)

Supplier: Genetex

Description: Rabbit polyclonal antibody to RAB27A (RAB27A, member RAS oncogene family)

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Catalog Number: (89352-250)

Supplier: Genetex

Description: Mouse monoclonal [DM1B] to beta Tubulin

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Catalog Number: (89266-424)

Supplier: Genetex

Description: Rabbit polyclonal antibody to C11ORF57 (Middle)

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Catalog Number: (89336-482)

Supplier: Genetex

Description: Mouse monoclonal [2B8] to Lactoferrin

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Catalog Number: (89272-210)

Supplier: Genetex

Description: Mouse monoclonal antibody [9H10] to RNF144B

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Catalog Number: (89276-560)

Supplier: Genetex

Description: Rabbit polyclonal antibody to Dok2 (phospho Y299)

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Catalog Number: (89268-592)

Supplier: Genetex

Description: Rabbit polyclonal antibody to GALNTL4 (Middle)

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Catalog Number: (89351-518)

Supplier: Genetex

Description: This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. The N-terminus of this gene contains a mitochondrial targetting signal, essential for mitochondrial localization.

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Catalog Number: (89365-378)

Supplier: Genetex

Description: Rabbit polyclonal antibody to SCF

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Catalog Number: (89280-080)

Supplier: Genetex

Description: Rabbit Polyclonal antibody to TNFRSF12A (tumor necrosis factor receptor superfamily member 12A) Purity: Protein G purified Species Reactivity: Human Tested Applications: WB Pkg Size: 200 ul

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