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Supplier: AAT BIOQUEST INC
Description: SK1 is an anti-human monoclonal antibody that is specific for the CD8a antigen.

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Supplier: AAT BIOQUEST INC
Description: AAT Bioquest's iFluor® dyes are optimized for labeling proteins, in particular, antibodies.

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Supplier: AAT BIOQUEST INC
Description: Gentamicin is widely used for treating tuberculosis and Gram-negative infections and is particularly useful in neonatal intensive care units. Fluorophore-tagged drugs, such as gentamicin-Texas Red (GTTR) conjugates, have been used to identify drug trafficking routes across the BLB and into hair cells, and specifically in the cochlea - the sensory organ responsible for hearing. Identifying the mechanisms involved in the intracochlear trafficking of ototoxic drugs to hair cells is of fundamental as well as clinical importance. Texas Red-gentamicin conjugate (GTTR) provides researchers a valuable tool to study the cellular uptake, kinetics and distribution of gentamicin through fluorescence techniques, such as fluorescence microscopy, fluorescence correlation spectroscopy, single molecule spectroscopy. The TR fluorophore can be conveniently excited from 500-600 nm, with an emission maximum centered around 610 nm. Acute nephrotoxicity and permanent ototoxicity are serious side-effects that increase patient morbidity, or induce permanent auditory and vestibular deficits. Several approaches have been used to study the intracellular mechanisms induced by ototoxic drugs. However, ototoxic drugs must first cross the blood-labyrinth barrier (BLB) before entering sensory hair cells to exert their cytotoxic effect that leads to hearing loss and deafness. The BLB is similar to the blood-brain barrier (BBB), and is composed of tight junction-coupled endothelial and epithelial barrier layers that transport nutrients and ions from one side of the barrier to the other.

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Supplier: AAT BIOQUEST INC
Description: HP-3G10 is an anti-human monoclonal antibody that recognizes the CD161 antigen.

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Supplier: AAT BIOQUEST INC
Description: AAT Bioquest's iFluor® dyes are optimized for labeling proteins, in particular, antibodies.

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Catalog Number: (76484-248)
Supplier: AAT BIOQUEST INC
Description: Cal-520® provides a robust homogeneous fluorescence-based assay tool for detecting intracellular calcium mobilization.

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Supplier: AAT BIOQUEST INC
Description: AAT Bioquest's iFluor® dyes are optimized for labeling proteins, in particular, antibodies.

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Supplier: AAT BIOQUEST INC
Description: MycoLight™ Green JJ98 stain is an excellent green-fluorescent nuclear and chromosome counterstain that is permeant to both prokaryotic and eukaryotic cell membranes.

Catalog Number: (76483-442)
Supplier: AAT BIOQUEST INC
Description: ADP is involved in many biological reactions such as protein kinases.

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Catalog Number: (76482-340)
Supplier: AAT BIOQUEST INC
Description: Nicotinamide adenine dinucleotide (NAD+) and nicotinamide adenine dinucleotide phosphate (NADP+) are two important cofactors found in cells.

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Supplier: AAT BIOQUEST INC
Description: Calcium flux assays are preferred methods in drug discovery for screening G protein coupled receptors (GPCR).

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Catalog Number: (76482-336)
Supplier: AAT BIOQUEST INC
Description: MCLA has been used to assess superoxide formation in a variety of conditions, including neutrophil and macrophage activation, cultured cells and vascular tissue.

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Catalog Number: (76485-662)
Supplier: AAT BIOQUEST INC
Description: Mca-YVADAPK(Dnp)-OH is a fluorogenic peptide substrate for detecting caspase-1/interleukin-converting enzyme (ICE) and angiotensin I-converting enzyme-2 (ACE-2).

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Supplier: AAT BIOQUEST INC
Description: TAQuest™ qPCR Master mix for TaqMan probes is a ready-to-use 2X solution optimized for qPCR and two-step RT-qPCR compatible with TaqMan gene expression assays.

Supplier: AAT BIOQUEST INC
Description: Calcium measurement is critical for numerous biological investigations.

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Supplier: AAT BIOQUEST INC
Description: L17F12 is an anti-human monoclonal antibody that is specific for the CD5 antigen.

Small Business Enterprise Minority or Woman-Owned Business Enterprise

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

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  • State issued document with your organization's Federal Tax ID Number
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* Please note if your account is within the State of California two of these pieces of identification will be required.
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