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Catalog Number: (102552-394)
Supplier: BioVendor
Description: Interleukin-6 is a multi-functional cytokine that regulates immune responses, acute phase reactions and hematopoiesis, and it may play a central role in host defense mechanisms.


Catalog Number: (102552-108)
Supplier: BioVendor
Description: Caspases are the executioners of apoptosis.


Catalog Number: (102552-256)
Supplier: BioVendor
Description: GM-CSF is a small glycoprotein growth factor which stimulates the production and function of neutrophils, eosinophils and monocytes.


Catalog Number: (102552-860)
Supplier: BioVendor
Description: Total 87 AA. MW: 9.88 kDa (calculated). UniProtKB acc.no. Q13296. N-Terminal His-tag (12 extra AA)


Catalog Number: (101215-418)
Supplier: BioVendor
Description: Leptin, the product of the ob (obese) gene, is a single-chain 16 kDa proteohormone consisting of 146 amino acid residues. Leptin is produced by differentiated adiocytes, although production have been demonstrated in other tissues, such as fundus of the stomach, the sceletal muscle, the liver, and the placenta. Leptin is considered to play an important role in appetite control, fat metabolism and body weight regulation. It targets the central nervous system, in particular the hypothalamus, suppressing food intake and stimulating energy expenditure. In humans, leptin levels correlate with body mass index (BMI) and percentage body fat, and are elevated even in obese individuals. Leptin has a dual action; it decreases the appetite and increases energy consumption, causing more fat to be burned.


Catalog Number: (101189-712)
Supplier: BioVendor
Description: Uromodulin (Tamm-Horsfall protein, UMOD) is approx. 85-kDa glycoprotein that is produced in the thick ascending limb of Henle´s loop and early distal convoluted tubules of the nephron. It is a transmembrane protein, which is secreted into the urine through proteolytic cleavage of the glycosylphosphatidylinositol (GPI) anchor. It belongs to the GPI family. Healthy individuals excrete tens of miligrams of uromodulin per day, making in the most abundant protein in the urine. Uromodulin modulates cell adhesion and signal transduction by interacting with cytokines and it inhibits the aggregation of calcium crystals. By reducing calcium oxalate precipitation, uromodulin plays a protective role with respect to renal stone formation as demonstrated by recent studies on THP- deficient mice prone to nephrolithiasis. THP acts as a host defense factor against urinary tract infections induced by uropathogens such as Esherichia coli, Staphylococcus saphrophyticus, Proteus mirabilis and Klebsiela pneumonie. Uromodulin binds to type 1 fimbriae of Escherichia coli and thereby blocks colonization of urothelial cells. Tamm-Horsfall protein interacts with other molecules and cells including IL-1, IL-2, TNF, IgG, neuthrophils, lymphocytes and monocytes. Binding of uromodulin to neutrophils induces synthesis of IL-8, provokes the respiratory burst and degranulation and stimulates chemotaxis and phagocytosis. Recently, genome-wide association studies identified uromodulin as a risk factor for chronic kidney disease and hypertension. Mutations in the Uromodulin gene are associated with three autosomal dominant tubulo-interstitial nephropathies such as familial juvenile hyperuricemic nephropathy (FJHN), medullary cystic kidney disease (MCKD2) and glomerulocystic kidney disease (GCKD). These disorders are characterized by juvenile onset of hyperuricemia, gout and progressive renal failure.


Catalog Number: (102552-588)
Supplier: BioVendor
Description: Thrombomodulin converts thrombin into a physiologic anticoagulant.


Catalog Number: (101076-600)
Supplier: BioVendor
Description: Caspase-1 is the best-described inflammatory caspase.


Catalog Number: (102552-440)
Supplier: BioVendor
Description: Interleukin-6 is a multi-functional cytokine that regulates immune responses, acute phase reactions and hematopoiesis, and it may play a central role in host defense mechanisms.


Catalog Number: (101215-240)
Supplier: BioVendor
Description: Agouti-related protein is an endogenous antagonist of hypothalamic alpha-melanocortin receptors MC3R and MC4R with potent orexigenic activity. Although a complete deletion of the AGRP gene does not produce any significant metabolic phenotypes, reduction in AGRP expression by RNA interference is associated with increased metabolic rate along with reduced weight gain.


Catalog Number: (103739-826)
Supplier: BioVendor
Description: HUMAN NEURITIN E.COLI REC PROT 0.025MG


Catalog Number: (104074-946)
Supplier: BioVendor
Description: ELISA HUMAN MMP-2


Catalog Number: (104074-994)
Supplier: BioVendor
Description: ELISA HUMAN PHOSPHOTYROSINE TIE-1


Catalog Number: (104074-968)
Supplier: BioVendor
Description: ELISA HUMAN ANTI-MULLERIAN HORMONE


Catalog Number: (103853-680)
Supplier: BioVendor
Description: LABPREP VIRAL DNA/RNA VACEZOR KT 300PREP


Catalog Number: (101076-800)
Supplier: BioVendor
Description: ANGPTL3 ANTI-HUMAN 0.1 MG


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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