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Product Image-102552-898

Human S100A16 (fromE. coli)

Catalog Number: (102552-898)
Supplier: BioVendor
Description: Total 113 AA. MW: 13,04 kDa (calculated). UniProtKB acc.no. Q96FQ6. N-Terminal His-tag, 10 extra AA
Product Image-101422-966

Human Native Rhu alpha-2 Microglobulin (from Plasma)

Catalog Number: (101422-966)
Supplier: BioVendor
Description: Alpha-2 Macroglobulin is a serine proteases inhibitor, which inhibits coagulation by inactivating thrombin and Kallikrein, it inhibits fibrinolysis by inactivating plasmin and involved in insulin transport. Alpha-2-Macroglobulin is a large plasma protein, which is produced by the liver, it’s composed of 4 identical subunits bound together by -S-S- bonds. A2M is able to inactivate many kinds of proteinases (including serine-, cysteine-, aspartic- and metalloproteinases). A2M has a 35 amino acid "bait" region in its structure. Proteinases bind and cleave the “bait” region become bound to A2M. Macrophage receptors recognize the proteinase-A2M complex and clear it from the system. A2M binds to and removes MMP-2 and MMP-9 (active forms of the gelatinase) from the circulation using scavenger receptors on the phagocytes. The levels of Alpha-2-macroglobulin are increased in nephrotic syndrome which is a condition where the kidneys start to leak out some of the smaller blood proteins. Due to its large size, A2-macroglobulin is retained in the bloodstream. Increased production of all proteins causes A2-macroglobulin concentration to increase. Chronic renal failure might lead to amyloid by alpha-2-macroglobulin. A2M is raised in cirrhosis, pregnancy and diabetes.
Product Image-102552-928

Human Myelin FABP (from E. coli)

Catalog Number: (102552-928)
Supplier: BioVendor
Description: Total 140 AA. MW: 15.93 kDa (calculated). N-Terminal His-tag (9 extra AA)
Product Image-101215-406

Mouse Adiponectin (from HEK293 cells)

Catalog Number: (101215-406)
Supplier: BioVendor
Description: Adiponectin, also referred to as Acrp30, AdipoQ and GBP-28, is a recently discovered 244 aminoacid protein, the product of the apM1 gene, which is physiologically active and specifically and highly expressed in adipose cells. The protein belongs to the soluble defence collagen superfamily; it has a collagen-like domain structurally homologous with collagen VIII and X and complement factor C1q-like globular domain. Adiponectin forms homotrimers, which are the building blocks for higher order complexes found circulating in serum. Together, these complexes make up approximately 0.01% of total serum protein. Adiponectin receptors AdipoR1 and AdipoR2 have been recently cloned; AdipoR1 is abundantly expressed in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. Paradoxically, adipose tissue-expressed adiponectin levels are inversely related to the degree of adiposity. Adiponectin concentrations correlate negatively with glucose, insulin, triglyceride concentrations, liver fat content and body mass index and positively with high-density lipoprotein-cholesterol levels, hepatic insulin sensitivity and insulin-stimulated glucose disposal.
Product Image-102552-562

Stem Cell Factor Receptor, CD117, Human ELISA, BioVendor

Catalog Number: (102552-562)
Supplier: BioVendor
Description: Stem cell factor is a cytokine that binds to the c-Kit receptor (CD117).
Image Unavailable-101076-596

Endo Trap® HD Leakage ELISA, Biovendor

Catalog Number: (101076-596)
Supplier: BioVendor
Description: 96 wells (1 kit) - ELISA is a competitive enzyme immunoassay for the quantitative measurement of endotoxin.
Product Image-102552-866

Human AIF1 (from E. coli)

Catalog Number: (102552-866)
Supplier: BioVendor
Description: Allograft inflammatory factor 1 (AIF-1), is a 17kDa cytoplasm, calcium-binding protein that in humans is encoded by the AIF1 gene. This gene is induced by cytokines and interferon. Three transcript variants encoding different isoforms have been found for this gene. The AIF1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat. Allograft inflammatory factor 1 plays a important role in vascular inflammation. AIF-1 is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. AIF-1 also plays an important role in immune response and vasculopathy in allografts.
Product Image-101215-276

Human Spla2-Iie (from E. coli)

Catalog Number: (101215-276)
Supplier: BioVendor
Description: Phospholipase A2 (PLA2) catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to liberate arachidonic acid (AA), a precursor of eicosanoids including prostaglandins and leukotrienes. The same reaction also produces lysophosholipids, which represent another class of lipid mediators.
Product Image-101215-270

Human Myostatin Propeptide H (from E. coli)

Catalog Number: (101215-270)
Supplier: BioVendor
Description: Myostatin (GDF 8) is expressed uniquely in human skeletal muscle as a 12 kDa mature glycoprotein consisting of 109 amino acid residues and secreted into plasma. Myostatin is a member of the transforming growth factor β superfamily of secreted growth and differentiation factors that is essential for proper regulation of skeletal muscle mass. Studies have shown that myostatin could play an important role in cardiac development and physiology. In serum, myostatin circulates as part of a latent complex containing myostatin propeptide and/or follistatin-related gene. The myostatin propeptide is known to bind and inhibit myostatin in vitro. This interaction is relevant in vivo, with a majority (>70%) of myostatin in serum bound to its propeptide. The myostatin propeptide is negative regulator of myostatin in vivo. Total 248 AA. MW: 28 kDa (calculated). UniProtKB acc.no. O14793. 243 AA of recombinant human Myostatin Propeptide and 5 extra AA.
Product Image-102552-274

sICAM-3 Human ELISA, BioVendor

Catalog Number: (102552-274)
Supplier: BioVendor
Description: Intercellular Adhesion Molecule-3 (ICAM-3) is a member of the immunoglobulin supergene family and functions as a ligand for the Lymphocyte Function-Associated Antigen-1 (LFA-1).
Product Image-101422-270

Phosphoethanolamine/phosphocholine phosphatase Human E. coli, 0.1 mg

Catalog Number: (101422-270)
Supplier: BioVendor
Description: Total 295 AA. MW: 31.3 kDa (calculated). UniProtKB acc.no. Q8TCT1. N-Terminal His-tag 14 AA (highlighted).
Image Unavailable-101189-710

Dog Native LRG (from Serum)

Catalog Number: (101189-710)
Supplier: BioVendor
Description: Leucine-rich alpha-2-glycoprotein (LRG) is a secretory type 1 acute phase protein whose expression is upregulated by the mediators of acute-phase response. The level of LRG in the blood increases during microbial infections and cancer, presumably as a result of the liver’s response to pro-inflammatory cytokines . The function of LRG is unknown but it is proved that LRG is tightly binding to Cyt C. It is suggested that extracellular Cyt C that is released from the cell death by an acute inflammation could be trapped to form tight complex with LRG and be excluded from circulation. LRG secretion by human hepatoma cells is increased by treatment with a mixture of cytokines including IL-6, IL-1b, and TNFα that are known to induce acute-phase proteins.
Image Unavailable-103737-176

Cell Clock Assay Kit

Catalog Number: (103737-176)
Supplier: BioVendor
Description: The Cell-Clock Assay is a live-cell detection and measurement system that can be employed to monitor the four major phases of the mammalian cell cycle during in vitro culture
Product Image-101422-314

IGFBP-2 Mouse/Rat ELISA, BioVendor

Catalog Number: (101422-314)
Supplier: BioVendor
Description: IGFBP-2 is, after IGFBP-3, the second most frequent IGFBP in the human blood.
Product Image-102552-694

Angiopoietin-Like Protein 3, ANGPTL 3, Mouse/Rat ELISA, BioVendor

Catalog Number: (102552-694)
Supplier: BioVendor
Description: ANGPTL3 is structurally similar to angiopoietins, which are vascular endothelial growth factors.
Product Image-102552-068

Alpha-Fetoprotein Human ELISA, BioVendor

Catalog Number: (102552-068)
Supplier: BioVendor
Description: AFP is normally produced during fetal and neonatal development by the liver, yolk sac, and in small concentrations by the gastrointestinal tract
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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