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Anti-CD34 Mouse Monoclonal Antibody [clone: 8G12] (FITC)

Catalog Number: (MSPP-60121FI)
Supplier: Stemcell Technologies
Description: Mouse monoclonal IgG1 antibody against human CD34, FITC-conjugated.

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Image Unavailable-MSPP-78042

Mouse Recombinant IL-3

Supplier: Stemcell Technologies
Description: Interleukin 3 (IL-3) is a species-specific pleiotropic cytokine that promotes the survival and proliferation of pluripotent hematopoietic stem cells and lineage-committed progenitor cells and their differentiation into mature cells of most lineages, including mast cells, basophils, neutrophils, eosinophils, macrophages, dendritic cells, erythrocytes, and megakaryocytes (Fung <i>et al.</i>; Metcalf <i>et al.</i>; Broughton <i>et al.</i>). IL-3 is produced by activated T cells, and has a physiological role in inflammation and allergies by promoting the secretion of inflammatory mediators such as histamine, IL-4, and IL-6 by mast cells, basophils and eosinophils. The mouse IL-3 receptor consists of a unique alpha-subunit (CD123) and two beta subunits, one specific for IL-3 (βIL-3), the other shared with the receptors for IL-5 and GM-CSF (beta common chain, βc or CD131). IL-3 binding to heterodimeric receptors containing the alpha subunit and one of either beta subunits activates JAK/STAT, MAPK, and PI3K signaling pathways (Scott and Begley).

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StemSpan™-XF Medium

Catalog Number: (MSPP-100-0073)
Supplier: Stemcell Technologies
Description: Xeno-free and serum-free medium for culture and expansion of human hematopoietic cells.

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Image Unavailable-MSPP-60030AZ

Anti-CD45 Rat Monoclonal Antibody [clone: 30-F11] (APC)

Supplier: Stemcell Technologies
Description: Rat monoclonal IgG2b antibody against mouse CD45, APC-conjugated.

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Image Unavailable-MSPP-60013AZ1

Anti-CD34 Mouse Monoclonal Antibody [clone: 581] (APC)

Catalog Number: (MSPP-60013AZ1)
Supplier: Stemcell Technologies
Description: Mouse monoclonal IgG1 antibody against human CD34, APC-conjugated.

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Image Unavailable-MSPP-782163

Human Recombinant IL-31

Supplier: Stemcell Technologies
Description: Interleukin 31 (IL-31), a four-helix bundle inflammatory cytokine, belongs to the IL-6 cytokine family which includes IL-6 (MSPP-78050), oncostatin M (MSPP-78094), leukemia inhibitory factor (LIF; MSPP-78055), and cardiotrophin-1 (Dillon <i>et al.</i>). IL-31 signals through a heterodimer composed of IL-31RA (also known as gp130-like receptor or GPL) and the oncostatin-M receptor (OSMR), both of which are expressed on monocytes (Diveu <i>et al.</i>; Ghilardi <i>et al.</i>), epithelial cells (Ip <i>et al.</i>), and keratinocytes (Kato <i>et al.</i>). Signaling through the GPL/OSMR complex activates the JAK/STAT, RAS/ERK, and PI3K/AKT signaling pathways, resulting in the downstream activation of STAT1, STAT3, and STAT5 transcription factors (Cornelissen <i>et al.</i>; Dambacher <i>et al.</i>; Dillon <i>et al.</i>; Ip <i>et al.</i>). IL-31 responses have been associated with allergic responses and inflammatory skin diseases including atopic dermatitis (Cornelissen <i>et al.</i>; Gangemi <i>et al.</i>).

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Image Unavailable-MSPP-17661

EasySep™ Human APC Positive Selection Kit II

Catalog Number: (MSPP-17661)
Supplier: Stemcell Technologies
Description: Immunomagnetic positive selection of human cells labeled with APC-conjugated antibodies.
Image Unavailable-MSPP-100-1350

Anti-CD154 (CD40L) Mouse Monoclonal Antibody [clone: 5C8] (APC)

Catalog Number: (MSPP-100-1350)
Supplier: Stemcell Technologies
Description: Mouse monoclonal antibody against human CD154 (CD40L).

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Image Unavailable-MSPP-100-0520

STEMdiff™ Hepatocyte Kit

Catalog Number: (MSPP-100-0520)
Supplier: Stemcell Technologies
Description: Serum-free differentiation kit for the generation of hepatocyte-like cells from human PSCs.
Image Unavailable-MSPP-100-1618

Anti-CD69 Hamster Monoclonal Antibody [clone: H1.2F3] (APC)

Catalog Number: (MSPP-100-1618)
Supplier: Stemcell Technologies
Description: Hamster (Armenian) monoclonal antibody against mouse CD69, APC-conjugated.

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Image Unavailable-MSPP-100-0996

Mitochondrial Tracking Dye, Blue

Catalog Number: (MSPP-100-0996)
Supplier: Stemcell Technologies
Description: Fluorescent hydrophobic dye that selectively accumulates in mitochondria - 500 tests.

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Image Unavailable-MSPP-60130

Anti-Ym1 Rabbit Polyclonal Antibody

Catalog Number: (MSPP-60130)
Supplier: Stemcell Technologies
Description: Rabbit polyclonal IgG antibody against mouse Ym1, unconjugated.

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Image Unavailable-MSPP-07919

Gentle Collagenase/Hyaluronidase

Catalog Number: (MSPP-07919)
Supplier: Stemcell Technologies
Description: 10X Gentle collagenase/hyaluronidase in DMEM.
Image Unavailable-MSPP-60005AZ1

Anti-CD19 Mouse Monoclonal Antibody [clone: HIB19] (APC)

Catalog Number: (MSPP-60005AZ1)
Supplier: Stemcell Technologies
Description: Mouse monoclonal IgG1 antibody against human, chimpanzee CD19, APC-conjugated.

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Image Unavailable-MSPP-100-1299

Human Recombinant Sclerostin, His Tag

Catalog Number: (MSPP-100-1299)
Supplier: Stemcell Technologies
Description: Use sclerostin to alter bone remodeling homeostasis, where it inhibits bone formation in vivo and in vitro, likely through Wnt/β-catenin signaling cascades (Ellies <i>et al.</i>; Lin <i>et al.</i>). Sclerostin is a member of the cerberus/DAN family of glycoproteins whose members share a C-terminal cysteine-knot-like (CTCK) domain. Highly expressed in bone and cartilage, as well as in kidney, and liver tissues (Weivoda <i>et al.</i>), this osteoclast-derived BMP antagonist binds BMP6 and BMP7 with high affinity, and binds BMP2 and BMP4 with a lower affinity (Kusu <i>et al.</i>). Mutations in the SOST gene have been associated with sclerosteosis (Brunkow <i>et al.</i>), van Buchem disease (Staehling-Hampton <i>et al.</i>), and bone dysplasia disorders, characterized by increased bone density. This protein product contains a His-residue tag at the carboxyl end of the polypeptide chain. For consistency and reproducibility across your applications, sclerostin from STEMCELL comes lyophilized with ≥87% purity, and endotoxin levels are verified to be ≤1.0 EU/μg protein.

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Image Unavailable-MSPP-60030FI1

Anti-CD45 Rat Monoclonal Antibody [clone: 30-F11] (FITC)

Catalog Number: (MSPP-60030FI1)
Supplier: Stemcell Technologies
Description: Rat monoclonal IgG2b antibody against mouse CD45, FITC-conjugated.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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