You Searched For: EGV-Fritz

Catalog Number: (MSPP-76018)

Supplier: Stemcell Technologies

Description: Trans-activating crRNA for guide RNA generation in CRISPR-Cas9 genome editing.

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Catalog Number: (MSPP-10961)

Supplier: Stemcell Technologies

Description: Serum-free medium for differentiation of human monocytes to macrophages.

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Catalog Number: (MSPP-78041)

Supplier: Stemcell Technologies

Description: Fibroblast growth factor 18 (FGF-18) is a growth factor and member of the FGF subfamily. FGF-18 is most similar to FGF-8 and FGF-17, and is secreted in adult lung and developing tissues (Ohbayashi <i>et al.</i>). FGF-18 signals through FGF receptor 3 (FGFR3) to regulate proliferation, differentiation, and matrix production of articular and growth plate chondrocytes <i>in vivo</i> and <i>in vitro</i> (Davidson <i>et al.</i>). FGF-18 has skeletal functions and protects articular cartilage by gene expression profiling and regulates proliferation and differentiation of midline cerebellar structures (Mori <i>et al.</i>). Also, recombinant human FGF-18 has been shown to effectively regulate hair growth (Song <i>et al.</i>).

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Catalog Number: (MSPP-01993)

Supplier: Stemcell Technologies

Description: For detection and measurement of human immunoglobulin E.

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Catalog Number: (MSPP-08005)

Supplier: Stemcell Technologies

Description: Serum- and xeno-free kit for differentiation and expansion of human pluripotent stem cell-derived endothelial cells.

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Catalog Number: (MSPP-07060)

Supplier: Stemcell Technologies

Description: 3% Acetic Acid with Methylene Blue. Reagent for manual counting of nucleated mammalian cells

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Supplier: Stemcell Technologies

Description: Bone morphogenetic protein 2 (BMP-2) is a member of the transforming growth factor beta (TGF-β) superfamily. BMP-2 is a disulfide-linked homodimer, acts as a ligand for complexes of type I and II BMP receptors, and primarily activates SMAD1/5/8 signaling (Nohe <i>et al.</i>). BMP-2 is a potent differentiation factor and directs human pluripotent stem cells (hPSCs) towards various cell types including extra-embryonic endoderm, mesenchymal cells, and chondrocytes (Pera <i>et al.</i>). Although BMP-2 expression is low in healthy cartilage, its expression is upregulated at the site of cartilage damage (Blaney Davidson <i>et al.</i>). BMP-2 induces bone and cartilage formation <i>in vitro</i> and is able to induce chondrogenesis in human mesenchymal stem cells (Schmitt <i>et al.</i>).

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Catalog Number: (MSPP-02016)

Supplier: Stemcell Technologies

Description: For detection and measurement of human interleukin 23.

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Catalog Number: (MSPP-781001006)

Supplier: Stemcell Technologies

Description: RANTES (regulated upon activation, normal T cell expressed and secreted), also known as CCL5, is a member of the CC family of chemokines and is able to recruit leukocytes to sites of inflammation (Schall <i>et al.</i>). RANTES is secreted by T lymphocytes, macrophages, platelets, synovial fibroblasts, tubular epithelium, and certain types of tumor cells (Aldinucci and Colombatti; Soria and Ben-Baruch). This chemokine exerts its effect by interacting with the chemokine receptors CCR1, CCR3, CCR4, and CCR5. RANTES plays an active role in recruiting a variety of leukocytes into inflammatory sites, including T cells, macrophages, eosinophils, and basophils. In collaboration with certain cytokines that are released by T cells such as IL-2 and IFN-γ, RANTES also induces the activation and proliferation of NK cells to generate CC chemokine-activated killer cells, which are highly cytolytic (Lv <i>et al.</i>; Maghazachi <i>et al.</i>). It has been shown that RANTES produced by CD8+ T cells inhibits HIV infection of primary human peripheral blood mononuclear cells (Appay and Rowland-Jones; Cocchi <i>et al.</i>).

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Catalog Number: (MSPP-17847)

Supplier: Stemcell Technologies

Description: Immunomagnetic depletion of human TCRa/b+ cells.

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Catalog Number: (MSPP-100-1622)

Supplier: Stemcell Technologies

Description: Hamster (Armenian) monoclonal antibody against mouse CD80 (B7-1), PE-conjugated.

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Catalog Number: (MSPP-17683)

Supplier: Stemcell Technologies

Description: Immunomagnetic positive selection of any cells labeled with biotinylated antibodies.

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Catalog Number: (MSPP-20164)

Supplier: Stemcell Technologies

Description: RoboSep™ Buffer 2 is recommended for select EasySep™ cell separation protocols.

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Catalog Number: (MSPP-780481006)

Supplier: Stemcell Technologies

Description: Interleukin 5 (IL-5) is a member of the short-chain 4-α-helical bundle subset of hematopoietic cytokines. It binds to a receptor consisting of IL-5Ra, which is specific for IL-5R, and common beta chain, which is shared with the receptor for IL-3 and GM-CSF (Shearer). Upon binding to its receptor, IL-5 activates the JAK/STAT and MAPK pathways. IL-5 is produced by Th2 cells, eosinophils, and activated mast cells. It functions in the recruitment, activation, proliferation, and survival of eosinophils, thus playing an important role in allergic inflammation, asthma, and parasite immunity. Stimulation of eosinophils with IL-5 leads to their activation, upregulation of CD11b expression, and inhibition of apoptosis (Shearer).

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Catalog Number: (MSPP-60119PE)

Supplier: Stemcell Technologies

Description: Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD34, PE-conjugated.

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Supplier: Stemcell Technologies

Description: Interleukin 5 (IL-5) is a member of the short-chain 4-α-helical bundle subset of hematopoietic cytokines. It binds to the specific α receptor, which in turn recruits the common β receptor that initiates signaling via JAK/STAT and MAPK pathways. IL-5 is produced by Th2 cells, eosinophils, activated mast cells, and ILC2 cells. IL-5 affects the differentiation, activation, and survival of eosinophils, thus playing an important role in allergic inflammation, asthma, and parasite immunity. Stimulation of eosinophils with IL-5 leads to their activation, upregulation of CD11b expression, and inhibition of apoptosis (Shearer).

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