Description: For digestion of the extracellular matrix of cartilage.

Catalog Number: MSPP-07465

Supplier: Stemcell Technologies

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Description: Culture medium kit for establishment and maturation of human pluripotent stem cell-derived choroid plexus organoids.

Catalog Number: MSPP-100-0824

Supplier: Stemcell Technologies

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Description: Immunomagnetic positive selection of human CD33+ and CD66+ cells (e.g. myeloid cells).

Catalog Number: MSPP-17893

Supplier: Stemcell Technologies

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Description: Myostatin is a member of transforming growth factor beta (TGF-β) superfamily that signals by binding to activin type II receptor, resulting in the recruitment of either ALK3 or ALK4 coreceptor, and activation of SMAD2/3 (Kondás <i>et al.</i>). It is released by myocytes and inhibits muscle growth and ability to regenerate (Lee and Lee). Myostatin appears to affect the lipid catabolic metabolism of adipocytes and inhibits preadipocyte differentiation, as demonstrated in the 3T3-L1 cell line (Li <i>et al.</i>).

Catalog Number: MSPP-78119

Supplier: Stemcell Technologies

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Description: Immunomagnetic positive selection of mouse CD11c+ cells (e.g. dendritic cells (DC)) from mouse splenocytes or other tissues

Catalog Number: MSPP-18780

Supplier: Stemcell Technologies

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Description: Fibroblast growth factor 7 (FGF-7) is a member of the FGF family, and acts exclusively through a subset of FGF receptor isoforms expressed predominantly by epithelial cells (Finch and Rubin). FGF-7 seems to act specifically on epithelial cells and stimulates proliferation, migration, and differentiation of these cells, and also participates in epithelial protection and repair both <i>in vitro</i> and <i>in vivo</i> (Finch and Rubin; Werner). In contrast, FGF-7 is produced solely by cells of mesenchymal origin, and functions as a paracrine mediator of mesenchymal-epithelial communication (Rubin <i>et al.</i>). FGF-7 has also been shown to supplement several wound-healing properties of bioengineered skin (Erdag <i>et al.</i>) and to induce autophagy in human keratinocytes (Belleudi <i>et al.</i>). Additionally, FGF-7 has a role in pluripotent stem cell differentiation to endodermal pancreatic-like insulin-producing cells and thymic epithelial cells (Inami <i>et al.</i>; Niu <i>et al.</i>).

Catalog Number: MSPP-780462

Supplier: Stemcell Technologies

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Description: Immunomagnetic isolation of untouched non-human primate T cells

Catalog Number: MSPP-19581

Supplier: Stemcell Technologies

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Description: Stimulating T cells with CMV (HLA Class I Control) Peptide Pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. CMV Peptide Pool is a lyophilized mixture of 14 peptides from the human cytomegalovirus (CMV) and consists of defined HLA class I-restricted T cell epitopes. Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development. For consistency and reproducibility across your applications, CMV Peptide Pools from STEMCELL are formulated as lyophilized trifluoroacetate salts, with a purity ≥ 95%.

Catalog Number: MSPP-100-1414

Supplier: Stemcell Technologies

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Description: Immunomagnetic isolation of untouched human memory CD4+ T cells

Catalog Number: MSPP-19157

Supplier: Stemcell Technologies

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Description: Immunodensity isolation of untouched CD4+ T cells.

Catalog Number: MSPP-015062

Supplier: Stemcell Technologies

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Description: Count cells manually at a fraction of the cost and footprint of automated cell counters by using the Hausser Scientific™ Bright-Line hemocytometer.

Catalog Number: MSPP-100-1181

Supplier: Stemcell Technologies

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Description: Immunomagnetic positive selection of human CD4+ cells (e.g. CD4+ T cells).

Catalog Number: MSPP-17852

Supplier: Stemcell Technologies

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Description: Immunomagnetic positive selection of human cells with your own mouse IgG1 antibody.

Catalog Number: MSPP-17699

Supplier: Stemcell Technologies

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Description: Immunomagnetic positive selection of particle-free human cells labeled with APC-conjugated antibodies.

Catalog Number: MSPP-100-0031

Supplier: Stemcell Technologies

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Description: Betacellulin is a member of the epidermal growth factor (EGF) family, and signals through EGF receptor and ERBB4. It activates ERK and AKT pathways, which induces neural stem cell proliferation and prevents spontaneous differentiation in culture. Betacellulin stimulates the expansion of neural stem cells, transit-amplifying cells, and neuroblasts derived from subventricular zone and dentate gyrus (Gómez-Gaviro <i>et al.</i>). It is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Betacellulin down-regulates E-cadherin expression in ovarian cancer cell lines via MEK/ERK1/2 and PI3K/AKT signaling pathways, thus increasing cell migration (Zhao <i>et al.</i>). It is a modulator of interferon (IFN) response and enhances anti-viral effects of IFN (Al-Yahya <i>et al.</i>). Betacellulin is expressed in pancreatic α cells, β cells, and duct cells. It induces the proliferation of pancreatic cancer cell lines, inhibits apoptosis, promotes the neogenesis of β cells, and converts non-β cells into insulin-producing cells (Kawaguchi <i>et al.</i>; Miyagawa al.; Saito <i>et al.</i>).

Catalog Number: MSPP-781052

Supplier: Stemcell Technologies

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Description: Defined animal component-free medium for the differentiation of human ES and iPS cells to definitive endoderm.

Catalog Number: MSPP-05110

Supplier: Stemcell Technologies

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