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Image Unavailable-103543-382

(S)-Citalopram oxalate

Catalog Number: (103543-382)
Supplier: Selleck Chemicals
Description: Escitalopram oxalate is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.
Image Unavailable-101763-346

Tofacitinib (CP-690550) citrate

Supplier: Selleck Chemicals
Description: Tofacitinib citrate (CP-690550 citrate) is a novel inhibitor of JAK with IC50 of 1 nM, 20 nM and 112 nM against JAK3, JAK2, and JAK1, respectively.

Image Unavailable-101759-290

GSK1070916 >97%

Supplier: Selleck Chemicals
Description: GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM

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Imiquimod 99%

Supplier: Selleck Chemicals
Description: Imiquimod is a novel synthetic agent with immune response modifying activity.

Image Unavailable-103548-726

HPI-4 (Ciliobrevin A), Powder

Supplier: Selleck Chemicals
Description: HPI-4 (Ciliobrevin A) is a hedgehog (Hh) pathway antagonist. It blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of Smo.

Image Unavailable-103544-844

Brexpiprazole

Supplier: Selleck Chemicals
Description: Brexpiprazole is a novel D2 dopamine and serotonin 1A partial agonist, called serotonin-dopamine activity modulator (SDAM), and a potent antagonist of serotonin 2A receptors, noradrenergic alpha 1B and 2C receptors with Ki values of 0.3, 0.12, 0.47, 0.17 and 0.59 nM for D2L, 5-HT1A, 5-HT2A, α1B receptors and α2C receptors respectivey.

Image Unavailable-101764-074

β-Sitosterol ~97% (by HPLC)

Supplier: Selleck Chemicals
Description: β-Sitosterol is one of several phytosterols (plant sterols) with chemical structures similar to that of cholesterol.

Image Unavailable-101760-860

Nebivolol hydrochloride ≥99.4%

Supplier: Selleck Chemicals
Description: Nebivolol HCl selectively inhibits β1-adrenoceptor with IC50 of 0.8 nM.

Image Unavailable-101760-492

MG-132

Supplier: Selleck Chemicals
Description: MG-132 is a potent cell-permeable inhibitor of proteasome and calpain with an IC<sub>50 </sub>of 100 nM.

Image Unavailable-101756-742

Astragaloside A

Supplier: Selleck Chemicals
Description: Astragaloside A (Astragaloside IV) is the primary pure saponin isolated from <i>Astragalus membranaceus</i>, which has been widely used for the treatment of cardiovascular diseases.

Image Unavailable-101760-682

MLN-9708

Supplier: Selleck Chemicals
Description: MLN9708 gets hydrolyzed to its biologically active form MLN2238, on exposure to aqueous solutions or plasma

Image Unavailable-103543-876

(S)-Citalopram oxalate 10 mM in DMSO

Catalog Number: (103543-876)
Supplier: Selleck Chemicals
Description: Escitalopram oxalate is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.
Image Unavailable-101757-882

Cladribine 99.5%

Catalog Number: (101757-882)
Supplier: Selleck Chemicals
Description: Cladribine is an adenosine deaminase inhibitor for U266, RPMI8226, and MM1.S cells with IC50 of approximately 2.43, 0.75 and 0.18 μM, respectively
Image Unavailable-101761-458

(R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodophenylamino)benzamide ~99%

Supplier: Selleck Chemicals
Description: PD0325901 (PD325901) is selective and non ATP-competitive MEK inhibitor with an IC50 of 0.33 nM, roughly 500-fold more potent than CI-1040 on the phosphorylation of ERK1 and ERK2.

Image Unavailable-101762-232

Raltegravir

Supplier: Selleck Chemicals
Description: Raltegravir is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM in cell-free assays, respectively. It shows greater than 1000 fold selectivity for HIV-1 IN over several related Mg<sup>2+ </sup>dependent enzyme such as HCV polymerase, HIV reverse transcriptase, HIV RNaseH and human α-, β-, γ-polymerases.

Image Unavailable-101761-950

Posaconazole 99%

Supplier: Selleck Chemicals
Description: Posaconazole is an inhibitor primarily of CYP3A4, but it does not inhibit the activity of other CYP enzymes; Also an inhibitor of sterol C14ɑ demethylase inhibitor with IC50 of 0.25 μM.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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