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Description: This antibody is specific to bcl-2 oncoprotein, encoded by a gene involved in the 14;18 chromosomal translocation. In lymphoid tissues, this antibody stains B lymphocytes as well as T cells.
Catalog Number: 99990-844
Supplier: Diagnostic Biosystems


Description: This antibody recognizes keratin polypeptide of 54 kDa. It stains strongly with non-squamous epithelium but does not stain squamous epithelium. It reacts with the sweat gland and ducts in the skin. Adenocarcinomas of the ovary, gastrointestinal tract, ductal carcinoma of breast, pancreas and bile ducts, stain positive with this antibody.
Catalog Number: 76634-364
Supplier: Diagnostic Biosystems


Description: This antibody does not show any cross-reactivity with kappa light chain. It stains B cell follicles in human lymphoid tissues. The mantle zone shows a mosaic pattern of labeling while the germinal centers show a coarse meshwork pattern of staining.
Catalog Number: 99990-902
Supplier: Diagnostic Biosystems


Description: This antibody reacts with an unknown antigen on microvilli of mesothelioma cells. It stains normal mesothelial cells as well as epithelial mesotheliomas in a thick membrane pattern due to abundant lung microvilli on the surface of these cells.
Catalog Number: 76633-734
Supplier: Diagnostic Biosystems


Description: UnoVue Rabbit AP Detection Reagent is a non-biotin one-step detection reagent suitable for demonstrating antigens in formalin-fixed paraffin-embedded tissues and frozen sections.
Catalog Number: 10065-152
Supplier: Diagnostic Biosystems


Description: This antibody reacts with an antigen expressed by normal and neoplastic T cells and myeloid lineage cells. It strongly stains T cells in the interfollicular areas of normal lymphoid tissues.
Catalog Number: 76634-316
Supplier: Diagnostic Biosystems


Description: This antibody reacts with free as well as bound kappa light chains. Contaminating antibodies have been removed by solid phase adsorption.
Catalog Number: 99991-070
Supplier: Diagnostic Biosystems


Description: This antibody reacts with a 32 kDa protein. Caspase 3 is a member of the interleukin-1 β-converting enzyme family. Caspase 3 is thought to be associated with induction of apoptosis. Caspase 3 is synthesized as inactive 32 kDa proenzyme and is processed during apoptosis generating two subunits of 17 kDa and 12 kDa. Caspase 3 stains the epithelial cells of skin, renal proximal tubules and collecting ducts.
Catalog Number: 95024-926
Supplier: Diagnostic Biosystems


Description: This antibody reacts with P. carinii in the fixed human tissues. The antibody is specific against an 82 kDa parasite specific polypeptide. It does not cross-react with G. lamblia, T. gondii, T. cruzi, L. tropica, E. histolytica, C. albicans and P. falciparum.
Catalog Number: 76633-270
Supplier: Diagnostic Biosystems


Description: ERG, the ETS related gene, belongs to the ETS family that plays important roles in cell development, differentiation, proliferation, apoptosis and tissue remodeling. The ERG antibody identifies endothelial cells, lymphocytes and prostate cancer cells.
Catalog Number: 76634-864
Supplier: Diagnostic Biosystems


Description: Cytokeratin 5 (58 kDa) is a high molecular weight, basic type of cytokeratin expressed in basal, intermediate and superficial cell layers of stratified epithelia as well as transitional epithelia, complex epithelia and in mesothelial cells and mesothelioma. Cytokeratin 6 (56 kDa) is also a high molecular weight, basic type cytokeratin expressed by proliferating squamous epithelium often paired with cytokeratin 16.
Catalog Number: 76633-766
Supplier: Diagnostic Biosystems


Description: This antibody is specific to 160 kDa protein known as Factor XIII-A. Factor XIII is a β-globulin found in plasma and is composed of two subunits, Factor XIII-A and Factor XIII-B. Factor XIII-A is the catalytic subunit and is a dimer of M.W. 160 kDa. Factor XIII is a dermal dendrocyte marker and v variable reaction with these types of tumors.
Catalog Number: 76633-662
Supplier: Diagnostic Biosystems


Description: This antibody reacts with an unknown antigen on microvilli of mesothelioma cells. It stains normal mesothelial cells as well as epithelial mesotheliomas in a thick membrane pattern due to abundant lung microvilli on the surface of these cells.
Catalog Number: 76634-386
Supplier: Diagnostic Biosystems


Description: This antibody reacts with a protein of 60 kDa. E2Fs are DNA-binding proteins, which associate with negative regulators, such as the retinoblastoma P107 protein, resulting in an altered rate of gene transcription. E2F-1 is proposed to be involved in several cellular processes that range from tumor suppression, cell progression and oncogenesis. E2F-1 over expression can also drive cells into apoptosis.
Catalog Number: 76633-794
Supplier: Diagnostic Biosystems


Description: This antibody is specific to a 48 kDa protein, which is identified as cytokeratin 16. Cytokeratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region. High concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins.
Catalog Number: 76633-564
Supplier: Diagnostic Biosystems


Description: The antibody is specific against human α-1-antitrypsin. This antibody stains macrophages in human tissues and does not stain any other cell type.
Catalog Number: 76635-052
Supplier: Diagnostic Biosystems


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