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Description: This antibody recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Catalog Number: 75954-944
Supplier: Biotium


Description: HCG-alphA, Monoclonal antibody, Clone: HCGa/53, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Recombinant hCG alpha protein, Application: Immunohistology (formalin), Size: 500uL
Catalog Number: 75949-986
Supplier: Biotium


Description: Thyroglobulin, Monoclonal antibody, Clone: 6E1, Host: Mouse, Species reactivity: Mouse, Rat, Human, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: Human thyroid follicular cells, Synonyms: AITD3, Application: Immunohistology (formalin), Flow cytometry, Size: 100uL
Catalog Number: 75975-110
Supplier: Biotium


Description: This conjugate is prepared by labeling F(ab’)2 fragment of goat anti-rabbit IgG (H+L) with CF™647 dye. CF™ dyes offer advantages in brightness, photostability, and specificity compared to other fluorescent dyes. Far-red fluorescent CF™647 (Ex/Em 650/665 nm) is brighter than Cy®5 and an excellent alternative to Alexa Fluor® 647 for antibody conjugates.

Alexa Fluor® is a registered trademark of Thermo Fisher Scientific. Cy®5 is a registered trademark of GE Healthcare.
Catalog Number: 89138-478
Supplier: Biotium


Description: This MAb recognizes extracellular epitope of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.
Catalog Number: 75887-576
Supplier: Biotium


Description: This antibody reacts with five invariable CD3 chains designated CD3y, CD3d, CD3e, CD3f, and CD3n with molecular weight ranging from 16-28 kDa. It is found on all mature T-lymphocytes, NK, T-cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation. It is expressed, typically at high levels, on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and, in cortical thymus, CD3 is predominantly intracytoplasmic. This MAb is particularly useful for induction of T cell activation in vitro and in vivo due to its unusual IgG3 isotype.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®680R is a near-infrared fluorescent dye (Ex/Em 680/701 nm) with unrivaled photostability. It also is validated in super-resolution imaging by STED and single-molecule spectroscopy.
Catalog Number: 75895-516
Supplier: Biotium


Description: This antibody recognizes a protein of 55 kDa, identified as CD14 (also known lipopolysaccharide receptor). CD14 is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation.
Catalog Number: 75887-470
Supplier: Biotium


Description: CD68 Monoclonal antibody, Clone: C68/684 + KP1, Host: Mouse, Species reactivity: Human, Monkey, Cat, Isotype: IgG1, kappa, Conjugate: purified, Immunogen: Subcellular fraction, Synonyms: GP110, LAMP4, Application: IF, IHC, FC, Size: 500 uL
Catalog Number: 75915-834
Supplier: Biotium


Description: Kappa Light Chain, Monoclonal antibody, Clone: HP6053 + L1C1, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Purified human Ig kappa chain (HP6053) & Human B-Lymphoma Cells (L1C1), Synonyms: HCAK1, Size: 500uL
Catalog Number: 75955-220
Supplier: Biotium


Description: Cytokeratin 17 Monoclonal antibody, Clone: E3, Host: Mouse, Species reactivity: Goat, Pig, Cow, Rat, Human, Isotype: IgG2b, kappa, Conjugate: CF568, Immunogen: The cytoskeletal fraction, Synonyms: K17, KRT17, PCHC1, Application: IF, IHC, IHC, Size: 100uL
Catalog Number: 75917-030
Supplier: Biotium


Description: Cytokeratin 8/18 Monoclonal antibody, Clone: C-43 + DC10, Host: Mouse, Species reactivity: Human, Isotype: IgG1, K, Conjugate: CF647, Immunogen: Cytoskeletal preparation from HeLa epitheliod carcinoma cells and PMC-42 breast carcinoma cells, Size: 100uL
Catalog Number: 75922-812
Supplier: Biotium


Description: Cytokeratin 6 Monoclonal antibody, Clone: LHK6, Host: Mouse, Species reactivity: Mouse, Human, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: A synthetic peptide of 11 amino acids from C-terminus of human keratin 6, Application: IF, IHC, FC, Size: 500uL
Catalog Number: 75919-996
Supplier: Biotium


Description: Anti-IgG Goat Polyclonal Antibody (CF™ 543)
Catalog Number: 71004-054
Supplier: Biotium


Description: Cytokeratin 8 Monoclonal antibody, Clone: H1 + TS1, Host: Mouse, Species reactivity: Human, Isotype: IgG2a, Conjugate: CF594, Immunogen: Keratin preparation from a human carcinoma, Synonyms: CYK8, CYKER, Cytokeratin Endo A, Application: IF, Size: 500 uL
Catalog Number: 75920-476
Supplier: Biotium


Description: CD16 Monoclonal antibody, Clone: ICO-116, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: CF488A, Immunogen: Human CD16 proteinUnigene 372679, Application: Immunofluorescence, Flow cytometry, Size: 500 uL
Catalog Number: 75888-602
Supplier: Biotium


Description: IDH1, Monoclonal antibody, Clone: IDH1/1152, Host: Mouse, Species reactivity: Human, Isotype: IgG1 and IgG2a, kappa, Conjugate: CF640R, Immunogen: Recombinant fragment (119 Amino acid residues around aa 280-420) of human IDH1 protein, Application: IF, IHC (formalin), Size: 500uL
Catalog Number: 75953-840
Supplier: Biotium