You Searched For: Bandelin Electronic GmbH &Co.KG

Catalog Number: (RL106-1102)

Supplier: Rockland Immunochemical

Description: Secondary Goat Anti-IgG (H&L) Reacts with Guinea Pig

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Catalog Number: (RL712-1933)

Supplier: Rockland Immunochemical

Description: Secondary Goat Anti-F(ab')2 Reacts with Rat

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Catalog Number: (RL100-4185P)

Supplier: Rockland Immunochemical

Description: 50ug. Peptide Concentration: 1 mg/mL (by weight). Buffer: 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2. Stabilizer: None. Sterile filtered liquid.

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Catalog Number: (RL601-1902)

Supplier: Rockland Immunochemical

Description: Secondary Goat Anti-IgG (H&L) Reacts with Cow (Bovine, Cattle)

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Catalog Number: (75934-874)

Supplier: Rockland Immunochemical

Description: The LIM homeobox transcription factor 1B (LMX1B) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1B regulates mid-hindbrain patterning; LMX1B-null mice embryos have a severe reduction in the number of midbrain dopaminergic neurons compared to wild-type. While LMX1B appears to be important for both the development and the survival of dopamine neurons, the related LMX1A is crucial for the differentiation of these cells. However, LMX1A and LMX1B function cooperatively to regulated the proliferation, specification and differentiation of midbrain dopaminergic neuronal progenitors.

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Catalog Number: (75929-736)

Supplier: Rockland Immunochemical

Description: LRRK2 is a large protein with multiple domains including several ankyrin, leucine-rich, and WD40 repeats, a Ras-like small GTPase family domain named Roc, and a kinase domain that is closely related to the RIP kinase domain. LRRK2 gene is expressed in brain as well as in other tissues such as lung, liver and heart. LRRK2 might be central to the pathogenesis of several major neurodegenerative diseases associated with parkinsonism. Several dominantly inherited missense mutations in the gene encoding LRRK2 have been identified in several families that exhibit a broad spectrum of neuropathological features. Anti-LRRK2 is ideal for researchers interested in Neuroscience, specifically parkinsonism, as well as pathways related to the Electron Transport Chain and Wnt Signaling.

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Catalog Number: (RL200-901-P11S)

Supplier: Rockland Immunochemical

Description: L1/ORF2 Antibody has been tested for use in ELISA.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 149.5 kDa in size corresponding to L1 Protein by western blotting in the appropriate cell lysate or extract.

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Catalog Number: (75929-558)

Supplier: Rockland Immunochemical

Description: The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. LASS5, also called Trh4, is a 392 amino acid endoplasmic reticulum, multi-pass membrane protein. Functioning as a dihydro-ceramide synthase, LASS5 is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl-ceramide) in a fumonisin B1-independent manner. It uses palmitoyl-CoA as an acyl donor and is involved in the synthesis of C14, C16 and C18-ceramide. LASS5 is the most abundantly expressed and predominant ceramide synthase isoform in lung epithelia. Recent studies show that LASS5 partially correct growth and apoptosis.

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Catalog Number: (RL6121420020.5)

Supplier: Rockland Immunochemical

Description: Anti-Rat Igg (Handl) (Goat) Antibody Dylight* 549 Conjugated (5 X 100Ug) - 612-142-002-0.5 Rat Igg (Handl) Antibody Dylight* 549 Conjugated 500Ug

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Catalog Number: (RL112-4139)

Supplier: Rockland Immunochemical

Description: Primary Rabbit Anti-RAT Red Blood Cell (RBC) Reacts with Rat

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Catalog Number: (75929-470)

Supplier: Rockland Immunochemical

Description: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA5 belongs to a subfamily within the KPNA family that also includes KPNA4 and 6 and is thought to be involved in NLS-dependent protein import into the nucleus.

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Catalog Number: (RL6057410020.5)

Supplier: Rockland Immunochemical

Description: Anti-Goat Igg (Handl) (Donkey) Antibody Dylight* 488 Conjugated (5 X 100Ug) - 605-741-002-0.5 Goat Igg (Handl) Antibody Dylight* 488 Conjugated 500Ug

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Catalog Number: (10799-526)

Supplier: Rockland Immunochemical

Description: The nuclear factor NF-kB plays key roles in development and immunity. ABIN3 (A20-binding inhibitor of NF-kB activation 3), also known as TNFAIP3-interacting protein 3 (TNIP3), is a novel negative feedback regulator of LPS-induced NF-kB activation. ABIN3 is a 39 kDa protein that negatively regulates NF-kB activation in response to TNF and LPS. ABIN3 is highly expressed in brain, thymus, lymph node, lung and fetal liver, with low expression in kidney, bone marrow. Through its interaction with A20, ABIN3 interferes with TRAF2-mediated transactivation signals and NF-kB inhibition is mediated by the ABIN-homology domain 2. ABIN3 has been found to be induced by Listeria infection and can be slightly downregulated by dexamethasone. Enhanced expression of ABIN3 in monocytes is associated with sepsis. Thus, ABIN3 is an IL-10-induced gene product capable of attenuating NF-kB in human macrophages yet is inoperative in mice and represents a basis for species-specific differences in IL-10 actions. At least four isoforms of ABIN3 are known to exist.

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Catalog Number: (75930-856)

Supplier: Rockland Immunochemical

Description: Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.

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Catalog Number: (75930-196)

Supplier: Rockland Immunochemical

Description: The myelin transcription factor 1 family, to which the myelin transcription factor 1-like protein (MYT1L) belongs, is expressed primarily in the developing central nervous system and recruits histone deacetylase (HDAC) to regulate neural transcription. Both MYT1L and the related protein MYT1 interact with SIN3B, a protein that mediates transcriptional repression by binding to HDACs, suggesting that the MYT1 family favor the silencing of genes during neural development. Recent studies suggest that polymorphisms of MYT1L may be associated with schizophrenia.

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Catalog Number: (RL011-001-297)

Supplier: Rockland Immunochemical

Description: Produced through a multi-stage process that includes delipidation, salt fractionation, ion-exchange chromatography, gel filtration, and affinity chromatography. No contaminating proteins are observed when assayed at a protein concentration of 20mg/mL against anti-whole serum or anti-fragment specific antisera. All immunoglobulin fragments are prepared from highly purified, whole molecules subject to enzymatic digestion.

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