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Catalog Number: (IC097740005)

Supplier: MP Biomedicals

Description: Microplate sealing tape used to provide a tight seal on 96-well plates to minimize evaporation and condensation for short and long term storage.

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Supplier: MP Biomedicals

Description: This concentrated solution was designed to safely clean laboratory plastics and glassware simply by soaking overnight

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Supplier: MP Biomedicals

Description: Sodium Selenite, Purity: approx 98%, Cas Number: 10102-18-8, Formula: Na2Seo3, Molecular Weight: 172.94, Appearance: Pale Gray Powder, Synonyms Selenious Acid, Disodium, Disodium Selenite, Natriumselenit, Selenious Acid, Disodium Salt, Cell Culture Reagent, Size: 10 G

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Supplier: MP Biomedicals

Description: Lysing matrix D is for rapid and reliable biological sample lysis from a wide variety of starting materials.

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Catalog Number: (IC7640105)

Supplier: MP Biomedicals

Description: This microplate sealing tape is suitable for all microplates for both short- and long-term storage, providing a tight seal to minimize evaporation and condensation.

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Supplier: MP Biomedicals

Description: Deoxyribonuclease from beef pancreas, DNase I, was first crystallized by Kunitz. It is an endonuclease which splits phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide yielding 5'-phosphate terminated polynucleotides with a free hydroxyl group on position 3'. The average chain of limit digest is a tetranucleotide. DNase I acts upon single chain DNA, and upon double-stranded DNA and chromatin. In the latter case, although histones restrict susceptibility to nuclease action, over a period of time nearly all chromatin DNA is acted upon. According to Mirsky and Silverman, this could result from the looseness of histone attachment to DNA. They found that lysine-rich histones more effectively block DNase access to DNA than arginine-rich histones. Billing and Bonner suggest that DNase attacks the histone-free strand of chromatin DNA. Schmidt, et. al.indicate that hydrolysis of the histone-free region of DNA strands accounts for the initial rapid action of the enzyme on chromatin. Bollum reports degradation of synthetic homopolymer complexes by DNase I. The intracellular functions of the enzyme are probably controlled by a DNase inhibitor, which according to Lazarides and Lindberg is actin.

Supplier: MP Biomedicals

Description: For convenience and safety, MP is pleased to offer premixed acrylamide and methylene-bis-acrylamide. Avoid handling of toxic powders, tedious weighings, and concern over spillage and waste. Each bottle contains our Ultra Pure Acrylamide and Ultra Pure N,N′-Methylene-bis-acrylamide in a choice of two sizes and three different ratios.

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Catalog Number: (IC19011050)

Supplier: MP Biomedicals

Description: N-Lauroylsarcosine is an anionic detergent.

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Supplier: MP Biomedicals

Description: Demecolcine, also known as colcemid, is a drug used in chemotherapy. It is closely related to the natural alkaloid colchicine with the replacement of the acetyl group on the amino moiety with methyl, but it is less toxic.
Demecolcine is an antineoplastic agent used to immobilize chromosomes by inactivating the spindle fiber mechanism during metaphase. Medically, Demecolcine has been used to improve the results of cancer radiotherapy by synchronising tumour cells at metaphase, the radiosensitive stage of the cell cycle.
Demecolcine depolymerizes microtubules; blocks mitosis at metaphase. Often in karyotyping and cell cycle research it is desirable to increase the yield of mitotic cells in a particular phase of the cell cycle. This can be achieved in a variety of ways with the most popular being the use of a cell cycle synchronizing agent such as demecolcine. Demecolcine will arrest cells in metaphase with no remarkable effect on the biochemical events in mitotic cells or in synchronized G1 and S phase cells. White blood cells are often treated with demecolcine to arrest cells in metaphase.

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Supplier: MP Biomedicals

Description: L-Tryptophan is an amino acid precursor of serotonin and melatonin.

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Supplier: MP Biomedicals

Description: Chloride form quaternary ammonium functionality.Strongly basic, macroreticular resin of moderately high porosity with benzyltrialkylammonium functionality.

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Supplier: MP Biomedicals

Description: Cholic acid is a biochemical solubilizing agent (a non-ionic, non-denaturing detergent). Occurs inconjugation with glycine or taurine in bile of most vertebrates.

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Supplier: MP Biomedicals

Description: Activators: Papain is activated by cysteine, sulfide, sulfite, etc

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Supplier: MP Biomedicals

Description: Leupeptin is a modified tripeptide reversible protease inhibitor of trypsin-like proteases and some cysteine proteases including endoproteinase Lys-C, kallikrein, papain, thrombin, cathepsin B, cathepsins H and L, trypsin, calpain, trypsin8 and plasmin. Effective concentration is typically 10-100 uM. Little to no inhibition is seen against pepsin, cathepsins A and D and alpha-chymotrypsin. When adjusted for molarity, all three salt forms are equally effective; however, the hydrochloride salt is usually less invasive in biological settings.

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Catalog Number: (IC15526501)

Supplier: MP Biomedicals

Description: (+)-Longifolene is a building block for the synthesis of hydroazulenes. It is also used in the preparation of dilongifolylborane, an effective chiral hydroborating agent.

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Supplier: MP Biomedicals

Description: Vitamin B12 plays a role in the synthesis of myelin. It is a cofactor for two enzymes, methionine synthase and L-methylmalonyl-CoA mutase. The compound is also used as an antipernicious anemia factor.

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