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Description: Cytokeratin, HMW Monoclonal antibody, Clone: KRTH/1076, Host: Mouse, Species reactivity: Human, Rat, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Recom human KRT76 protein, Synonyms: KRT2B, KRT2P, HUMCYT2A, Application: IF, WB, FC, Size: 100uL
Catalog Number: 75915-942
Supplier: Biotium


Description: Lambda Light Chain, Monoclonal antibody, Clone: ICO-106, Host: Mouse, Species reactivity: Human, Isotype: IgG2a, kappa, BSA-free, Immunogen: Purified IgG myeloma proteins coupled to polyaminostyren, Synonyms: BJP, Application: Immunofluorescence, Size: 50 uL
Catalog Number: 75956-236
Supplier: Biotium


Description: bcl-x, Monoclonal antibody,Clone: BX006 + 2H12, Host: Mouse, Species reactivity: Mouse, Pig, Rat, Human, Conjugate: CF640R, Immunogen: A synthetic peptide, aa 3-14 (Cys-QSNRELVVDFLS) of human Bcl-X protein (BX006 & 2H12), Synonyms: Bcl2l1, BCLX, Size: 500 ul
Catalog Number: 75885-278
Supplier: Biotium


Description: Anti-IgG Rabbit Polyclonal Antibody (CF™ 488A)
Catalog Number: 89493-072
Supplier: Biotium


Description: EGFr Monoclonal antibody, Clone: GFR1195, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Recom human EGFR protein, Synonyms: Erbb1, ERBB1, Application: IF, IHC, Size: 500 uL
Catalog Number: 75925-480
Supplier: Biotium


Description: Lambda Light Chain, Monoclonal antibody, Clone: LcN-2, Host: Mouse, Species reactivity: Human, Isotype: IgG2a, kappa, Conjugate: biotin, Immunogen: Purified IgG myeloma proteins coupled to polyaminostyren, Synonyms: BJP, Application: IF, Size: 500uL
Catalog Number: 75956-532
Supplier: Biotium


Description: MITF (microphthalmia transcription factor) is a basic helix-loop-helix-leucine-zipper (bHLH-Zip) transcription factor that regulates the development and survival of melanocytes and retinal pigment epithelium, and also is involved in transcription of pigmentation enzyme genes such as tyrosinase TRP1 and TRP2. MITF has been shown to be phosphorylated by MAP kinase in response to c-kit activation, resulting in upregulation of MITF transcriptional activity. Mutations of the MITF gene are associated with the autosomal dominant hereditary deafness and pigmentation condition, Waardenburg Syndrome type 2A. Multiple isoforms of MITF exist, including MITF-A, MITF-B, MITF-C, MITF-H, and MITF-M, which differ in the amino-terminal domain and in their expression patterns. The MITF-M isoform is restricted to the melanocyte cell lineage. This MAb recognizes a nuclear protein, which is expressed in the majority of primary and metastatic epithelioid malignant melanomas as well as in normal melanocytes, benign nevi and dysplastic nevi.
Catalog Number: 75961-586
Supplier: Biotium


Description: This antibody recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.
Catalog Number: 75966-714
Supplier: Biotium


Description: This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. The function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.
Catalog Number: 75960-264
Supplier: Biotium


Description: Cytokeratin, HMW Monoclonal antibody, Clone: KRTH/1076, Host: Mouse, Species reactivity: Human, Rat, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: Recom human KRT76 protein, Synonyms: KRT2B, KRT2P, HUMCYT2A, Application: IF, WB, FC, Size: 100uL
Catalog Number: 75918-196
Supplier: Biotium


Description: This antibody recognizes a protein of 110 kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin.This MAb is superb for staining of formalin/paraffin tissues.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.
Catalog Number: 75881-766
Supplier: Biotium


Description: This product is prepared by labeling F(ab’)2 fragment of goat anti-mouse IgG (H+L) with Allophycocyanin (APC). APC belongs to the family of phycobiliproteins, which are derived from cyanobacteria and eukaryotic algae. APC has absorption maxima at 650 and emission at 660 nm. Because of the high fluorescence quantum yield (~0.68), APC is by far the brightest dye for the 650 nm wavelength region.
Catalog Number: 10018-312
Supplier: Biotium

SDS


Description: is prepared by labeling affinity purified IgG (H+L) with an orange-red fluorescent dye CF555, one of an outst&ing series of CF dyes developed by Biotium. CF dyes are superior for antibody labeling by having combined advantages in brightness, photostability, & specificity.
Catalog Number: 89138-796
Supplier: Biotium


Description: This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Catalog Number: 75952-336
Supplier: Biotium


Description: S100, Monoclonal antibody, Clone: 4C4.9 + S100A1/1012, Host: Mouse, Species reactivity: Mouse, Cow, Rat, Human, Isotype: IgG2a, kappa, Conjugate: CF488A, Immunogen: Purified bovine brain S100 protein, Synonyms: Bpb; NEF; S100-A1; S100 Alpha Chain, Application: IF, Size: 100uL
Catalog Number: 75973-090
Supplier: Biotium


Description: CD38 is a type II transmembrane glycoprotein that is present on early B- and T-cell lineages and activated B- and T-cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B-cells, mitogen-activated T-cells, monocytes and Ig-secreting plasma cells. CD38 is expressed on CD34 cells. The CD34 CD38- population of hematopoietic stems cells defines the most pluripotent cells (e.g. blast colony forming cells).

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.
Catalog Number: 75895-116
Supplier: Biotium