You Searched For: stab2

Catalog Number: (103259-886)

Supplier: Southern Biotechnology

Description: CD5, also known as Lyt-1, is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B-cell antigen CD72. The frequency of CD5+ B cells exhibits strain-dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B-1 cells. Binding of CD5 on the T cell surface can augment alloantigen- or mitogen-induced lymphocyte proliferation and induces increased cytosolic free calcium, IL-2 secretion, and IL-2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T-cell and B-cell receptors.

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Catalog Number: (100245-288)

Supplier: Southern Biotechnology

Description: Donkey Anti-Rabbit IgG(H+L)-FITC antibody with minimal reactivity to human, mouse, and rat serum proteins for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.

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Catalog Number: (100243-792)

Supplier: Southern Biotechnology

Description: The CD45 antigen is an essential regulator of leukocyte activation and development and is now known to be a protein tyrosine phosphatase, e.g., CD45 is able to dephosphorylate the Src family of protein kinases. This activity is now known to be required for signal transduction induced by T and B cell antigen receptor engagement, cytokine signaling, and Fc receptor stimulation. The functional state of CD45 also has a pronounced effect on lymphocyte development. CD45 exists in multiple forms, such as the restricted variants (CD45R; see companion products 1660, 1665, 1675, 1685, and 1820) and as allelic forms CD45.1 (Ly-5.1) and CD45.2 (Ly-5.2). The former arises as a result of alternative splicing of different exons. The specificity of antibodies to CD45.1 and CD45.2 has been exploited in studies where resolution of donor and recipient cells is essential, such as in gene therapy or bone marrow transplantation. The monoclonal antibody A20 recognizes all mouse leukocytes expressing the CD45.1 allotype.

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Catalog Number: (103265-070)

Supplier: Southern Biotechnology

Description: Donkey Anti-Goat IgG(H+L)-Alexa Fluor 488 antibody with minimal reactivity to mouse and rat serum proteins for use in flow cytometry, immunohistochemistry, and western blotting assays.

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Catalog Number: (100245-574)

Supplier: Southern Biotechnology

Description: Chicken Bu-1b, a product of the Bu-1b allele, is expressed on the cell surface as a disulfide-linked homodimer. In 10-week-old H.B15 and H.B2 chickens, Bu-1 is found on 85-90% of bursal cells, 2-8% of thymocytes, 15-27% of spleen cells, and 2-18% of peripheral blood cells. It is also expressed on subsets of macrophages and monocytes but not on granulocytes, erythrocytes, or thrombocytes. In chickens heterozygous for the Bu-1 alleles (Bu-1a/b), Bu-1a does not exhibit allelic exclusion. The monoclonal antibody 5-11G2 reacts with lymphoid cells from CHA and H.B14Ab strains but does not react with cells from H.B14Aa

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Catalog Number: (100246-162)

Supplier: Southern Biotechnology

Description: CD14 is a 55 kDa glycosphosphatidylinositol (GPI)-anchored single chain glycoprotein. It is expressed on monocytes, macrophages, dendritic cells, and Langerhans cells. It is also weakly expressed on neutrophils. CD14 appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.

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Catalog Number: (100244-880)

Supplier: Southern Biotechnology

Description: The monoclonal antibody BB6-10A10 stains the following percentages of surface immunoglobulin (sIg) positive cells in porcine lymphoid tissues - 11-15% in peripheral blood, 22-23% in mesenteric lymph nodes, 79-87% in ileal Peyer’s patches (ILPP), 6-17 in spleen, and 0% in thymus. While identification of the antigen(s) that are found predominantly on ILPP B cells and which are recognized by BB6-10A10 is speculative, the antibody appears to react with an immature population of B cells in the follicles of ILPPs and with a subpopulation of sIglow B cells in lymph nodes.

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Catalog Number: (103260-050)

Supplier: Southern Biotechnology

Description: Goat Anti-Rabbit IgG Fab-HRP antibody with minimal reactivity to mouse and human serum proteins for use in ELISA assays.

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Catalog Number: (100244-902)

Supplier: Southern Biotechnology

Description: SouthernBiotech’s C57BL/6 Mouse Immunoglobulin Panel contains 0.1 mg of mouse IgA, mouse IgG1, mouse IgG2b, mouse IgG2c, mouse IgG3, and mouse IgM for use in immunoassays. The kit may be used as positive reference standards for isotyping and standards for quantitative studies of C57BL/6 mouse immunoglobulins in samples such as serum, supernatant, feces, and ascites.

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Catalog Number: (100242-680)

Supplier: Southern Biotechnology

Description: Goat Anti-Mouse IgG2a-HRP antibody with minimal reactivity to human proteins for use in ELISA, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.

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Catalog Number: (100243-834)

Supplier: Southern Biotechnology

Description: The monoclonal antibody YLI-90 reacts with the B6 allele of Ly49I, a member of the lectin-like homodimeric Ly49 family of cell surface receptors. Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells. The YLI-90 antibody stains ~45% of NK1.1+CD3- splenocytes from C57BL/6 mice.

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Catalog Number: (100244-166)

Supplier: Southern Biotechnology

Description: CD107b, also known as lysosomal-associated membrane protein 2 (LAMP-2), is a heavily glycosylated type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles. CD107b is similar in structure to Mac-1 and is expressed primarily on epithelial cells and macrophages in a variety of organs in normal and beige mutant mice.

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Catalog Number: (100246-130)

Supplier: Southern Biotechnology

Description: CD11b is the 165 kDa αM chain which combines with the CD18 β2 integrin subunit to form the Mac-1 heterodimer. It is expressed on activated lymphocytes, monocytes, granulocytes and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a ligand for C3bi, CD50 (ICAM-3), CD54 (ICAM-1) and CD102 (ICAM-2).

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Catalog Number: (103264-370)

Supplier: Southern Biotechnology

Description: Purified Goat F(ab')2 Anti-Mouse IgM antibody for use in ELISA and stimulation assays.

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Catalog Number: (100246-178)

Supplier: Southern Biotechnology

Description: CD14 is a 55 kDa glycosphosphatidylinositol (GPI)-anchored single chain glycoprotein. It is expressed on monocytes, macrophages, dendritic cells, and Langerhans cells. It is also weakly expressed on neutrophils. CD14 appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.

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Catalog Number: (100242-302)

Supplier: Southern Biotechnology

Description: Purified Anti-Human IL-3 antibody for use in flow cytometry, immunohistochemistry, ELISA, western blotting, and immunoprecipitation assays.

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