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Anti-IgG3 Goat Antibody (RPE (R-Phycoerythrin))

Catalog Number: (100242-760)
Supplier: Southern Biotechnology
Description: Goat F(ab’)2 Anti-Mouse IgG3-PE antibody with minimal reactivity to human proteins for use in flow cytometry assays.
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Anti-CD43 Mouse Monoclonal Antibody [clone: DF-T1]

Catalog Number: (100246-260)
Supplier: Southern Biotechnology
Description: CD43, a member of the sialomucin family of cell surface receptors, is a 95-135 kDa type I transmembrane glycoprotein whose variability in molecular weight is dependent upon the nature of the extracellular O-glycans. It is the major sialoglycoprotein on thymocytes, T cells, and neutrophils. It is also present on activated B cells, plasma cells, NK cells, granulocytes, monocytes, macrophages, platelets, and bone marrow hematopoietic stem cells. CD43, which binds to ICAM-1 (CD54), appears to function as an anti-adhesion molecule, inhibiting T cell interactions including T cell killing, and by increasing the threshold for T cell activation.
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Anti-IgG1 Mouse Antibody (HRP (Horseradish Peroxidase)) [clone: SB139a]

Catalog Number: (103264-694)
Supplier: Southern Biotechnology
Description: HRP Anti-Hamster IgG1 antibody for use in ELISA assays.
Image Unavailable-100245-494

Anti-CD8 beta Mouse Monoclonal Antibody (RPE (R-Phycoerythrin)) [clone: EP42]

Catalog Number: (100245-494)
Supplier: Southern Biotechnology
Description: In the chicken, the CD8 molecule is present in two forms - (i) a homodimer of two α chains and (ii) a heterodimer of an α chain and a β chain. While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8α- and CD8β-chains, a relatively large proportion of the CD8+ TCR-γδ cells in the spleens of embryos and young chicks express only the α-chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved but there is a population of TCR-γδ CD8αβ cells in the chicken that is not found in rodents. Chicken CD8 is expressed on approximately 80% of thymocytes, 45% of blood mononuclear cells, and 50% of spleen cells but less than 1% of cells in the bursa and bone marrow. The monoclonal antibody EP42 recognizes the CD8β chain.
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Anti-IgG (H+L) Donkey Antibody

Catalog Number: (103265-056)
Supplier: Southern Biotechnology
Description: Purified Donkey Anti-Mouse IgG(H+L) antibody with minimal reactivity to human, goat, sheep, bovine, rabbit, chicken, horse, and guinea pig serum proteins for use in ELISA and immunocytochemistry assays.
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Anti-CD154 Hamster Monoclonal Antibody [clone: MR1]

Catalog Number: (100243-502)
Supplier: Southern Biotechnology
Description: CD154, formerly known as CD40 ligand and gp39, is a type II integral membrane protein and a member of the tumor necrosis factor (TNF) family of ligands. It is an important accessory molecule in T cell-B cell costimulatory interactions and is expressed predominantly on activated CD4+ T lymphocytes. It is also present on the surface of activated Th0, Th1, and Th2 T cell clones. Its expression is transient and cyclosporin-sensitive. The MR1 monoclonal antibody binds to murine CD154 with high affinity, blocks binding to CD40, and blocks CD154 function. Administration of this antibody to mice blocks the ability to mount primary and secondary immune responses to TD antigens yet does not alter the immune response to TI antigens.
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Anti-CD105 Mouse Monoclonal Antibody (Alexa Fluor® 488) [clone: SN6]

Catalog Number: (103265-422)
Supplier: Southern Biotechnology
Description: CD105, also known as endoglin, is a 90 kDa type II transmembrane glycoprotein that is expressed on the cell surface as a disulfide-linked homodimer and is found on endothelial cells. CD105 is one of several receptors for the various isoforms of TGF which in turn is one of a family of proteins involved in regulation of cell differentiation, migration of cells, and control on the immune response.
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Anti-CD117 Rat Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: 2B8]

Catalog Number: (100243-994)
Supplier: Southern Biotechnology
Description: The CD117 (c-Kit) antigen is the cell-surface receptor for stem cell factor (SCF). Together these molecules constitute a ligand/receptor pair which functions to maintain normal hematopoiesis in the adult. Signaling through SCF/c-Kit has an important role in stimulating myeloid and erythroid production of primitive hematopoietic progenitor cells. A variety of cytokines act synergistically with SCF to stimulate proliferation and differentiation of bone marrow progenitor cells. For example, SCF plus IL-7 can stimulate the combined myeloid and B cell differentiation of uncommitted hematopoietic progenitor cells. SCF/c-Kit also participates in erythropoiesis in both the bone marrow and spleen. Loss-of-function mutations for SCF/c-Kit lead to a variety of pleiotropic developmental defects while gain-of-function mutations can lead to constitutive activation of the kit receptor and links to cancer. Examples of the former are mast cell deficiency and severe macrocytic anemia while the latter mutation has been identified in mastocytomas.
Image Unavailable-100244-328

Anti-IgA Goat Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (100244-328)
Supplier: Southern Biotechnology
Description: Goat F(ab')2 Anti-Human IgA-FITC antibody for use in flow cytometry and immunohistochemistry assays.
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Anti-CD54 Mouse Monoclonal Antibody (Biotin) [clone: 15.2]

Catalog Number: (103265-258)
Supplier: Southern Biotechnology
Description: CD54, also known as intercellular cell adhesion molecule-1 (ICAM-1), is a 90 kDa type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It exhibits a wide tissue distribution being expressed on both hematopoietic and non-hematopoietic cells. ICAM-1 expression on leukocytes is low but is rapidly upregulated upon activation. Expression on endothelium and other non-hematopoietic cells is strongly upregulated by inflammatory mediators. The ligands of CD54 are CD11a/LFA-1α and CD11b/Mac-1α. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels particularly in areas of inflammation. CD54 on antigen-presenting cells (APC) contributes to antigen-specific T cell activation presumably by enhancing interactions between T cells and APC.
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Rhesus Monkey IgG Isotype Control

Catalog Number: (100242-160)
Supplier: Southern Biotechnology
Description: Purified Rhesus Monkey IgG for use as a control in multiplex assays and as a standard in ELISA.
Image Unavailable-100245-144

Anti-IgG (H+L) Rabbit Antibody (TRITC (Tetramethylrhodamine Isothiocyanate))

Catalog Number: (100245-144)
Supplier: Southern Biotechnology
Description: Rabbit Anti-Goat IgG(H+L)-TRITC antibody for use in immunohistochemistry / immunocytochemistry assays.
Image Unavailable-101442-934

Anti-CD62E/CD62P Mouse Monoclonal Antibody (Spectral Red® RPE (R-Phycoerythrin)/Cy5®) [clone: 1.2B6]

Catalog Number: (101442-934)
Supplier: Southern Biotechnology
Description: CD62E represents the 97 kDa type I transmembrane glycoprotein E-selectin, also known as endothelial-leukocyte adhesion molecule-1 (ELAM-1). It is expressed on cytokine-stimulated endothelium, weakly on unactivated endothelium, and is absent on leukocytes. Like other selectins, CD62E is an adhesion molecule that contributes to the initial attachment and rolling of leukocytes on endothelial surfaces, a prerequisite for leukocyte extravasation into tissues. CD62P is a 140 kDa membrane glycoprotein formerly known as platelet activation-dependent granule membrane protein (PADGEM) or GMP-140. It is expressed on platelets, megakaryocytes, and epithelium. It is thought to mediate the adhesive interactions of neutrophils and monocytes with endothelium in inflammatory responses and of activated platelets to neutrophils and monocytes in hemostasis. The monoclonal antibody 1.2B6 recognizes a common epitope shared by CD62E and CD62P.
Image Unavailable-100246-524

Anti-CD107a Mouse Monoclonal Antibody (Spectral Red® RPE (R-Phycoerythrin)/Cy5®) [clone: H4A3]

Catalog Number: (100246-524)
Supplier: Southern Biotechnology
Description: CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. CD107a is expressed by activated T cells, macrophages, dendritic cells, activated platelets, tonsillar epithelium, and some tumor cell lines, including U937 and KG1a. It is also a widely expressed intracellular antigen. LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and CD107b on the surface of tumor cell lines has been associated with their enhanced metastatic potential where they may increase adhesion to extracellular matrix and endothelium.
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Anti-IgG Goat Antibody (bGal (beta Galactosidase))

Catalog Number: (100242-486)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG-β-galactosidase antibody with minimal reactivity to human proteins for use in ELISA and immunohistochemistry / immunocytochemistry assays.
Image Unavailable-103264-824

Anti-IgG (H+L) Goat Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (103264-824)
Supplier: Southern Biotechnology
Description: Goat Anti-Rat IgG-HRP antibody with minimal reactivity to mouse and human proteins for use in ELISA assays.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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