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Catalog Number: (100245-014)
Supplier: Southern Biotechnology
Description: Purified Goat F(ab')2 Anti-Hamster IgG(H+L) antibody with minimal reactivity to mouse and rat proteins for use in ELISA, flow cytometry, and immunohistochemistry assays.


Catalog Number: (100245-484)
Supplier: Southern Biotechnology
Description: Chicken CD45 is a transmembrane glycoprotein expressed on all leukocytes. B lineage cells in the bursa of Fabricius express the 215 kDa isoform while T lineage cells bear the 190 kDa variant. These high molecular weight molecules have intrinsic phosphotyrosine phosphatase activity characteristic of mammalian CD45. Levels of CD45 expression detected by the monoclonal antibody LT40 in the avian thymus are heterogeneous with approximately 90% of thymocytes expressing fourfold higher levels of surface CD45 (CD45hi) than do the remaining 10% (CD45low) of thymocytes. The CD45low population contains exclusively thymocytes with the CD3-CD4-CD8low phenotype characteristic of the immediate precursors to the CD3-CD4+CD8+ thymic population which are CD45hi. This shift from low to high levels of surface CD45 expression is concomitant with the transition from CD4-CD8low to CD4+CD8+ and before the expression of CD3. The ability of the monoclonal antibody LT40 to discriminate this CD45low subpopulation provides a suitable marker for the CD3-CD4-CD8low immediate precursors to the CD3-CD4+CD8+ thymocytes.


Catalog Number: (100242-458)
Supplier: Southern Biotechnology
Description: Low Endotoxin/Azide Free Goat F(ab')2 Anti-Mouse IgM antibody with minimal reactivity to human proteins for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, stimulation, and purification assays.


Catalog Number: (100245-746)
Supplier: Southern Biotechnology
Description: AP Anti-Human IgG2 Fd antibody for use in ELISA, immunohistochemistry, and western blotting assays.


Catalog Number: (100245-926)
Supplier: Southern Biotechnology
Description: CD20 is a 33-37 kDa unglycosylated phosphoprotein. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. It is expressed on all stages of B cell differentiation except plasma cells. The CD20 molecule is involved in regulation of B cell differentiation presumably via its reported function as a Ca++ channel subunit.


Catalog Number: (100243-474)
Supplier: Southern Biotechnology
Description: Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCRαβ+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B and T cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis.


Catalog Number: (103265-694)
Supplier: Southern Biotechnology
Description: CD11a, also known as leukocyte function-associated antigen-1 (LFA-1α), represents the 180 kDa integrin αL subunit which combines with the CD18 β2 integrin subunit to form the αLβ2 integrin heterodimer. It is expressed on lymphocytes, granulocytes, monocytes, and macrophages and is upregulated on activated T cells. CD11a mediates adhesion of lymphocytes to vascular endothelium and is involved in costimulation.


Catalog Number: (103259-692)
Supplier: Southern Biotechnology
Description: Rat IgG1-Alexa Fluor 647 for use as a control in flow cytometry and immunocytochemistry assays.


Catalog Number: (100246-408)
Supplier: Southern Biotechnology
Description: CD95, also known as Fas and APO-1, is a 45 kDa type I transmembrane glycoprotein and a member of the tumor necrosis factor receptor superfamily. It is expressed by activated lymphocytes, monocytes, neutrophils, fibroblasts, and cell lines. Fas ligand binding to CD95 induces apoptosis in activated mature lymphocytes thereby playing a role in maintaining peripheral tolerance.


Catalog Number: (100243-192)
Supplier: Southern Biotechnology
Description: The monoclonal antibody I21/7 reacts with the α subunit of mouse and human CD11a, also known as LFA-1, and a member of the integrin family of cell adhesion molecules. The antigen is expressed on thymocytes, T and B lymphocytes, and on non-lymphoid cells in the bone marrow. CD11a appears to be an essential component for T-cell activation by antigen-presenting cells and is important for cell-mediated killing. Costimulatory signaling by LFA-1 is achieved by pairing with its ligand, CD54/ICAM-1.


Catalog Number: (103259-822)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG2b-HRP antibody with minimal reactivity to human, bovine, and horse serum proteins for use in ELISA, western blotting, and immunocytochemistry assays.


Catalog Number: (100242-744)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG3-Texas Red antibody with minimal reactivity to human proteins for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.


Supplier: Southern Biotechnology
Description: CD19 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is expressed at all stages of B cell differentiation except terminally differentiated plasma cells. It is also present on the cell surface of follicular dendritic cells. CD19 associates with CD21, CD81, Leu 13 and/or MHC Class II molecules to form a signal transduction complex on the B cell surface. This signaling complex modulates the activation threshold for the B cell antigen receptor (BCR).

Catalog Number: (101442-844)
Supplier: Southern Biotechnology
Description: Purified Anti-Rabbit Ig antibody for use in ELISA and flow cytometry assays.


Catalog Number: (100244-978)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Porcine IgG(H+L) antibody for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (103264-366)
Supplier: Southern Biotechnology
Description: Goat F(ab’)2 Anti-Mouse IgM-Alexa Fluor 647 antibody with minimal reactivity to human proteins for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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