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Catalog Number: (100245-600)
Supplier: Southern Biotechnology
Description: Chicken Bu-1, a product of the Bu-1a and Bu-1b alleles, is a type I transmembrane glycosylated disulfide-linked homodimer. The monoclonal antibody AV20 recognizes a monomorphic determinant on the Bu-1 B cell-associated alloantigens of both RPL 6(3) (Bu-1a) and 7(2) (Bu-1b) lines of inbred chickens. The antibody also identifies B cells in partially inbred birds. Bu-1 is found on 85-90% of bursal cells, 2-8% of thymocytes, 15-27% of spleen cells, and 2-18% of peripheral blood cells. It is also expressed on subsets of macrophages and monocytes but not on granulocytes, erythrocytes, or thrombocytes. The monoclonal antibody AV20 does not cross react with turkey cells when analyzed by flow cytometry.


Catalog Number: (103265-150)
Supplier: Southern Biotechnology
Description: CD3 is a member of the T cell receptor-associated CD3 complex. The monoclonal antibody CT-3 recognizes a complex of at least three polypeptides of Mr 20, 19, and 17 kDa (two of which are N-glycosylated) on chicken T cells. The antibody also coprecipitates a polypeptide of 90 kDa from digitonin solubilized T cell lysates, which can be reduced to two polypeptides of Mr 50 and 40 kDa.


Catalog Number: (103264-676)
Supplier: Southern Biotechnology
Description: HRP Anti-Hamster IgG3 antibody for use in ELISA assays.


Catalog Number: (101442-822)
Supplier: Southern Biotechnology
Description: AP Anti-Rat IgG1 antibody for use in ELISA, immunohistochemistry, and ELISpot assays.


Catalog Number: (101442-594)
Supplier: Southern Biotechnology
Description: FITC Anti-Human IFN-gamma antibody for use in flow cytometry and immunohistochemistry / immunocytochemistry assays.


Catalog Number: (100244-336)
Supplier: Southern Biotechnology
Description: Goat Anti-Human Kappa-FITC antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, and western blotting assays.


Supplier: Southern Biotechnology
Description: CD90 (Thy-1), a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain. It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes, and neurons of all mouse strains. The monoclonal antibody G7 stimulates T-cell proliferation and IL-2 secretion via signaling through the T-cell receptor/CD3 complex. G7 has also been reported to promote apoptosis of thymocytes and CTL clones and to mediate adhesion of thymocytes to thymic stroma.

Catalog Number: (100244-340)
Supplier: Southern Biotechnology
Description: Goat Anti-Human Kappa-AP antibody for use in ELISA, immunohistochemistry / immunocytochemistry, western blotting, and ELISpot assays.


Catalog Number: (100242-052)
Supplier: Southern Biotechnology
Description: Purified Mouse IgE for use as a control in flow cytometry and western blotting assays and as a standard in ELISA.


Catalog Number: (101443-006)
Supplier: Southern Biotechnology
Description: CD74 represents a type II integral membrane protein known as MHC class II-associated invariant chain. It is moderately expressed on B cells and weakly on monocytes and macrophages. CD74 is also found on a subset of activated T cells, Langerhans cells, dendritic cells, and some epithelial cells. CD74 may play a role in antigen processing and presentation through intracellular transport and expression of class II molecules on the cell surface.


Catalog Number: (100246-006)
Supplier: Southern Biotechnology
Description: CD62E represents the 97 kDa type I transmembrane glycoprotein E-selectin, also known as endothelial-leukocyte adhesion molecule-1 (ELAM-1). It is expressed on cytokine-stimulated endothelium, weakly on unactivated endothelium, and is absent on leukocytes. Like other selectins, CD62E is an adhesion molecule that contributes to the initial attachment and rolling of leukocytes on endothelial surfaces, a prerequisite for leukocyte extravasation into tissues. CD62P is a 140 kDa membrane glycoprotein formerly known as platelet activation-dependent granule membrane protein (PADGEM) or GMP-140. It is expressed on platelets, megakaryocytes, and epithelium. It is thought to mediate the adhesive interactions of neutrophils and monocytes with endothelium in inflammatory responses and of activated platelets to neutrophils and monocytes in hemostasis. The monoclonal antibody 1.2B6 recognizes a common epitope shared by CD62E and CD62P.


Catalog Number: (103260-084)
Supplier: Southern Biotechnology
Description: FITC Anti-Monkey IgG for use in flow cytometry and western blotting assays.


Catalog Number: (100242-034)
Supplier: Southern Biotechnology
Description: Goat F(ab’)2 IgG-APC for use as a control in flow cytometry assays.


Catalog Number: (100245-514)
Supplier: Southern Biotechnology
Description: PE Anti-Chicken IgM antibody for use in flow cytometry assays.


Catalog Number: (100243-992)
Supplier: Southern Biotechnology
Description: The CD117 (c-Kit) antigen is the cell-surface receptor for stem cell factor (SCF). Together these molecules constitute a ligand/receptor pair which functions to maintain normal hematopoiesis in the adult. Signaling through SCF/c-Kit has an important role in stimulating myeloid and erythroid production of primitive hematopoietic progenitor cells. A variety of cytokines act synergistically with SCF to stimulate proliferation and differentiation of bone marrow progenitor cells. For example, SCF plus IL-7 can stimulate the combined myeloid and B cell differentiation of uncommitted hematopoietic progenitor cells. SCF/c-Kit also participates in erythropoiesis in both the bone marrow and spleen. Loss-of-function mutations for SCF/c-Kit lead to a variety of pleiotropic developmental defects while gain-of-function mutations can lead to constitutive activation of the kit receptor and links to cancer. Examples of the former are mast cell deficiency and severe macrocytic anemia while the latter mutation has been identified in mastocytomas.


Catalog Number: (100244-754)
Supplier: Southern Biotechnology
Description: Goat Anti-Rabbit IgG-TRITC antibody for use in immunohistochemistry / immunocytochemistry assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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