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Supplier: Biotium

Description: Cytokeratin 7 Monoclonal antibody, Clone: KRT7/760 + OV-TL12/30, Host: Mouse, Species reactivity: Human, Rat, Isotype: IgG1, K, Conjugate: purified, Immunogen: Recom full-length human KRT7, Synonyms: CK-7, Application: IF, Size: 500 uL

Supplier: Biotium

Description: Myogenin, Monoclonal antibody, Clone: F5D, Host: Mouse, Species reactivity: Pig, Dog, Cat, Rat, Human, Isotype: IgG2a, kappa, Conjugate: purified, Immunogen: Rat myogenin peptide (aa 73-94), recombinant fragment (aa30-224), Synonym:cb553, Size: 100uL

Supplier: Biotium

Description: FOXP3 Monoclonal antibody, Clone: FXP3/197, Host: Mouse, Species reactivity: Mouse, Monkey, Human, Isotype: IgG1, kappa, Conjugate: purified, Immunogen: Recombinant human full-length FOXP3 protein, Application: IF, Immunohistology, Size: 500 uL

Supplier: Biotium

Description: Cytokeratin 19 Monoclonal antibody, Clone: BA17, Host: Mouse, Species reactivity: Mouse, Human, Isotype: IgG2a, kappa, Conjugate: CF568, Immunogen: Human mammary epithelial organoids, Synonyms: k19, k1cs, krt19, Application: IF, IHC, FC, Size: 500 uL

Supplier: Biotium

Description: Hepatocyte Paraffin 1 or HepPar1 localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. The Hepatocyte Specific Antigen may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of the Hepatocyte Specific Antigen correlates with smaller tumor size and longer patient survival. Occasionally, Hepatocyte Specific Antigen is also found in gastric carcinomas as well as in a few other non-hepatic tumors.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Catalog Number: (75888-026)

Supplier: Biotium

Description: CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkins disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.

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Supplier: Biotium

Description: This MAb recognizes a protein of ~50 kDa which is identified as Glial Fibrillary Acidic Protein (GFAP). It shows no cross-reaction with other intermediate filament proteins. GFAP is specifically found in astroglia. GFAP is a very popular marker for localizing benign astrocyte and neoplastic cells of glial origin in the central nervous system. Antibody to GFAP is useful in differentiating primary gliomas from metastatic lesions in the brain and for documenting astrocytic differentiation in tumors outside the CNS.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Supplier: Biotium

Description: CD5 Monoclonal antibody, Clone: C5/473 + CD5/54/F6, Host: Mouse, Species reactivity: Rabbit, Cow, Rat, Human, Isotype: IgG2a &IgG1, K, Conjugate: CF640R, Immunogen: peptide, Synonyms: CD5 antigen (p56 62), LEU1, Application: IF, Size: 100uL

Supplier: Biotium

Description: This MAb recognizes a protein of 145 kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Supplier: Biotium

Description: This antibody recognizes a 27 kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This MAb co-precipitates cdk4 in complex p27Kip1 and is excellent for staining of formalin-fixed tissues.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Supplier: Biotium

Description: TRAcP (Tartarate Resistant Acid Phosphatase), Monoclonal antibody, Clone: ACP5/1070, Host: Mouse, Species reactivity: Mouse, Rat, Human, Isotype: IgG2b, kappa, Conjugate: biotin, Immunogen: Recombinant full-length human ACP5 protein, Application: IF, Flow cytometry, Size: 500uL

Supplier: Biotium

Description: CD66 Monoclonal antibody, Clone: C66/261, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Recom full-length human CEA protein, Synonyms: Cell Adhesion Molecule 5, Application: IF, IHC, Size: 500 uL

Supplier: Biotium

Description: This MAb recognizes a protein of 145 kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Catalog Number: (89427-060)

Supplier: Biotium

Description: Activated charcoal retains ethidium bromide, GelRed™ and GelGreen™ efficiently in a convenient bag for decontamination of used gel staining solutions. Each bag has a total capacity of at least 10 mg ethidium bromide.

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Catalog Number: (75924-632)

Supplier: Biotium

Description: This antibody recognizes a protein of 36 kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.

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Supplier: Biotium

Description: Mucin 1 / EMA / Episialin / CD227, Monoclonal antibody, Clone: MUC1/845, Host: Mouse, Species reactivity: Mouse, Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Human milk-fat globule membranes, Application: IF, Size: 500uL