You Searched For: ACCUFORM MANUFACTURING, INC

Description: Anti-IgG Goat Polyclonal Antibody (CF™ 647)

Catalog Number: 89493-106

Supplier: Biotium

Sale

Description: This antibody recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Catalog Number: 75966-152

Supplier: Biotium

Sale

Description: CD66 Monoclonal antibody, Clone: COL-1 + CEA31 + C66/261, Host: Mouse, Species reactivity: Human, Isotype: IgG1, K, Conjugate: CF594, Immunogen: Recom full-length human CEA, Synonyms: CEACAM5, Application: IF, Size: 100uL

Catalog Number: 75917-402

Supplier: Biotium

Sale

Description: CD195 / CCR-5 Monoclonal antibody, Clone: 12D1, Host: Mouse, Species reactivity: Human, Isotype: IgG2a, kappa, Conjugate: CF488A, Immunogen: Human native CCR5 protein, Synonyms: CC-CKR-5, CCCKR5, CCR5, Application: IF, IHC, FC, Size: 500 uL

Catalog Number: 75889-482

Supplier: Biotium

Sale

Description: This antibody recognizes a protein of 210-220 kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb does not block CR1 activity. It is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21 /CD35 /CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Catalog Number: 75894-452

Supplier: Biotium

Sale

Description: MUC2, Monoclonal antibody, Clone: CCP58, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: synthetic peptide of 29 amino acids, from MUC2 protein, Synonyms: Mucin-2, Intestinal mucin-2, Application: IF, Size: 500uL

Catalog Number: 75962-102

Supplier: Biotium

Sale

Description: This antibody neutralises HurTNFamediated cytotoxicity of L929 cells and inhibits tumour growth in mice. It protects mice against toxicity of HurTNFa. Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17 kDa band following SDS PAGE under non-reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumor Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production.

Catalog Number: 75976-818

Supplier: Biotium

Sale

Description: with CF660C. CF660C can still be sufficiently excited by the 633/635 nm laser with emission at 685 nm. CF660C is several fold brighter and significantly more photostable than Alexa Fluor 660.

Catalog Number: 89138-500

Supplier: Biotium

Sale

Description: This antibody recognizes a glycoprotein of 110 kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Catalog Number: 75917-542

Supplier: Biotium

Sale

Description: Anti-GFP Mouse Monoclonal Antibody (CF™ 633)

Catalog Number: 97065-674

Supplier: Biotium

Sale

Description: Proximal Nephrogenic Antigen / Renal Cell Carcinoma (RCC), Monoclonal antibody, Clone: PN-15, Host: Mouse, Species reactivity: Human, Horse, Isotype: IgG2b, kappa, BSA-free, Immunogen: human renal cortical tissue, Size: 50 uL

Catalog Number: 75971-240

Supplier: Biotium

Sale

Description: Fibronectin Monoclonal antibody, Clone: HFN7.1, Host: Mouse, Species reactivity: Human, Isotype: IgG1, K, Conjugate: CF568, Immunogen: Human fibronectin purified from serum, Synonyms: FN1, FNZ, GFND, GFND2, LETS, Application: IF, Size: 100uL

Catalog Number: 75926-870

Supplier: Biotium

Sale

Description: This antibody recognizes a protein of 55 kDa, which is identified as fascin-1. Its actin binding ability is regulated by phosphorylation. Antibody to fascin-1 is a very sensitive marker for Reed-Sternberg cells and variants in nodular sclerosis, mixed cellularity, and lymphocyte depletion Hodgkins disease. It is uniformly negative in lymphoid cells, plasma cells, and myeloid cells. Fascin-1 is also expressed in dendritic cells. This marker may be helpful to distinguish between Hodgkin lymphoma and non-Hodgkin lymphoma in difficult cases. Also, the lack of expression of fascin-1 in the neoplastic follicles in follicular lymphoma may be helpful in distinguishing these lymphomas from reactive follicular hyperplasia in which the number of follicular dendritic cells is normal or increased. Antibody to fascin-1 has been suggested as a prognostic marker in neuroendocrine neoplasms of the lung as well as in ovarian cancer. Fascin-1 expression may be induced by Epstein-Barr virus (EBV) infection of B cells with the possibility that viral induction of fascin in lymphoid or other cell types must also be considered in EBV-positive cases.

Catalog Number: 75926-316

Supplier: Biotium

Sale

Description: CD34 Monoclonal antibody, Clone: QBEnd/10, Host: Mouse, Species reactivity: Human, Rhesus monkey, Cynomolgus monkey, Isotype: IgG1, K, Conjugate: CF594, Immunogen: Detergent solubilized vesicular suspension prepared, Synonyms: HPCA1, Application: IF, Size: 100uL

Catalog Number: 75894-604

Supplier: Biotium

Sale

Description: This antibody recognizes a transcription factor of 64-67 kDa, identified as c-myc. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or over-expressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease. Rearrangement of the MYC gene is found in 3% to 16% of diffuse large B-cell lymphoma (DLBCL's) and in nearly 100% of Burkitt lymphomas (BL). Identifying MYC status is important in establishing final diagnosis of DLBCL, BL, or B-cell lymphoma, with features intermediate between DLBCL and BL as well as in differential diagnoses of the lymphomas.

Catalog Number: 75921-190

Supplier: Biotium

Sale

Description: This antibody recognizes a protein of 50-65 kDa, identified as CD16 (Workshop IV; Code N39 ) (also known low affinity Fc receptor III for IgG (FcRIII) or Leu 11). CD16 exists as a polypepetide-anchored from (FCRIIIA or CD16A) on human natural killer (NK) cells and monocytes/ macrophages and as a glycosylphosphatidylinositol (GPI)-anchored form (FcRIIIB or CD16B) on neutrophils. CD16B is polymorphic and the two alleles are termed NA1 and NA2.3 CD16 plays a role in signal transduction, NK cell activation and antibody-dependent cellular cytotoxicity. This MAb has been showed to inhibit the binding of immune complex to NK cells, inhibit cytotoxicity of NK cells, and induce calcium fluxes in NK cells and neutrophils.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Catalog Number: 75887-922

Supplier: Biotium

Sale