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Description: TRAcP (Tartarate Resistant Acid Phosphatase), Monoclonal antibody, Clone: ACP5/1070, Host: Mouse, Species reactivity: Mouse, Rat, Human, Isotype: IgG2b, kappa, Conjugate: biotin, Immunogen: Recombinant full-length human ACP5 protein, Application: IF, Flow cytometry, Size: 500uL
Catalog Number: 75977-568
Supplier: Biotium


Description: CD66 Monoclonal antibody, Clone: C66/261, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Recom full-length human CEA protein, Synonyms: Cell Adhesion Molecule 5, Application: IF, IHC, Size: 500 uL
Catalog Number: 75915-564
Supplier: Biotium


Description: This MAb recognizes a protein of 145 kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Catalog Number: 75886-450
Supplier: Biotium


Description: Activated charcoal retains ethidium bromide, GelRed™ and GelGreen™ efficiently in a convenient bag for decontamination of used gel staining solutions. Each bag has a total capacity of at least 10 mg ethidium bromide.
Catalog Number: 89427-060
Supplier: Biotium


Description: This antibody recognizes a protein of 36 kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Catalog Number: 75924-632
Supplier: Biotium


Description: Mucin 1 / EMA / Episialin / CD227, Monoclonal antibody, Clone: MUC1/845, Host: Mouse, Species reactivity: Mouse, Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Human milk-fat globule membranes, Application: IF, Size: 500uL
Catalog Number: 75963-790
Supplier: Biotium


Description: CD68 Monoclonal antibody, Clone: C68/684 + KP1, Host: Mouse, Species reactivity: Human, Monkey, Cat, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: Subcellular fraction, Synonyms: GP110, LAMP4, Application: IF, IHC, FC, Size: 500 uL
Catalog Number: 75915-872
Supplier: Biotium


Description: Cyclin A2 Monoclonal antibody, Clone: E67, Host: Mouse, Species reactivity: Mouse, Mink, Green monkey, Monkey, Cow, Human, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: Full length bovine Cyclin A, Synonyms: CCN1, CCNA, CCNA2, Application: IF, Size: 500 uL
Catalog Number: 75923-106
Supplier: Biotium


Description: PS2, Monoclonal antibody, Clone: GE2, Host: Mouse, Species reactivity: Human, Monkey, Isotype: IgG3, kappa, Conjugate: biotin, Immunogen: synthetic peptide from C-terminus of human TFF1 protein, Synonyms: BCEI, Breast Cancer Estrogen Inducible Protein, Application: IF, Size: 500uL
Catalog Number: 75972-108
Supplier: Biotium


Description: This antibody recognizes a 66 kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90% positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.
Catalog Number: 75977-740
Supplier: Biotium


Description: P55;50 EBV-Early Antigen, Monoclonal antibody, Clone: 1108-1, Host: Mouse, Species reactivity: EBV, Isotype: IgG1, kappa, Conjugate: CF488A, Synonyms: EBNA1; EBV nuclear antigen 1; Epstein Barr nuclear antigen 1, Application: Immunofluorescence, Size: 100uL
Catalog Number: 75967-754
Supplier: Biotium


Description: This antibody recognizes a protein of 210-220 kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb does not block CR1 activity. It is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21 /CD35 /CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.
Catalog Number: 75894-702
Supplier: Biotium


Description: beta-2 microglobulin Monoclonal antibody, Clone: BBM.1, Host: Mouse, Species reactivity: Human, Non-human primates, Isotype: IgG2b, K, Conjugate: CF568, Immunogen: MOLT-4 human T cell line, Synonyms: B2M, Application: IF, Size: 100uL
Catalog Number: 75884-288
Supplier: Biotium


Description: PTH / Parathyroid Hormone (N-Terminal), Monoclonal antibody, Clone: PTH/1173, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, Conjugate: CF647, Immunogen: synthetic peptide from N-terminal of PTH polypeptide, Synonyms: Parathyrin, Size: 100uL
Catalog Number: 75973-362
Supplier: Biotium


Description: CD171 / L1CAM Monoclonal antibody, Clone: UJ127, Host: Mouse, Species reactivity: Human, Isotype: IgG1, K, Conjugate: BSA-free, Immunogen: Homogenous suspension, Synonyms: CAML1, HSAS1, Hyd, MIC5, Application: IF, Flow cytomet, Size: 50 uL
Catalog Number: 75888-794
Supplier: Biotium


Description: This antibody recognizes a protein of ~55 kDa, identified as SOX10. This MAb is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly expressed in desmoplastic melanomas. SOX-10 is considered as a very reliable marker for recognizing residual desmoplastic melanomas. In normal tissues, it is expressed in Schwann cells, melanocytes, and myoepithelial cells of salivary, bronchial and mammary glands. SOX-10 expression is also observed in mast cells.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.
Catalog Number: 75975-672
Supplier: Biotium


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