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Description: CD106 / VCAM1 Monoclonal antibody, Clone: 1.4C3, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: Stimulated human umbilical vein endothelial cells, Synonyms: CD106, INCAM-100, L1CAM, Application: IF, Size: 500 uL

Catalog Number: 75885-760

Supplier: Biotium

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Description: beta-2 microglobulin Monoclonal antibody, Clone: BBM.1, Host: Mouse, Species reactivity: Human, Non-human primates, Isotype: IgG2b, K, Conjugate: CF594, Immunogen: MOLT-4 human T cell line, Synonyms: B2M, Application: IF, Size: 500 uL

Catalog Number: 75884-290

Supplier: Biotium

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Description: 5-CR110-X, SE (full name: 5-Carboxyrhodamine 110-X, succinimidyl ester) is the amine-reactive form of 5-carboxyrhodamine 110 with a 6-carbon spacer.

Catalog Number: 89139-542

Supplier: Biotium

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Description: The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Catalog Number: 75962-884

Supplier: Biotium

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Description: Phosphotyrosine, Monoclonal antibody, Clone: PY20, Host: Mouse, Species reactivity: All species, Isotype: IgG2b, Conjugate: CF647, Immunogen: Phosphotyrosine conjugated to KLH, Synonyms: P-Tyr, Application: Immunofluorescence, Size: 100uL

Catalog Number: 75970-106

Supplier: Biotium

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Description: This antibody recognizes a cell surface glycoprotein of 80-95 kDa (CD44) on lymphocytes, monocytes, and granulocytes (Leucocyte Typing Workshop V). Its epitope is resistant to digestion by trypsin and chymotrypsin. This MAb selectively interferes with lymphocyte binding to lymph node, mucosal and synovial endothelium. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95 kDa or hematopoietic variant (CD44s). Higher molecular weight isoforms are described in epithelial cells (CD44v), which are believed to function in intercellular adhesion and stromal binding. CD44 immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.

Catalog Number: 75911-192

Supplier: Biotium

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Description: This antibody recognizes a protein of 21 kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.

Catalog Number: 75884-470

Supplier: Biotium

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Description: This MAb recognizes cytokeratin 4, 5, 6, 8, 10, 13, and 18. This is a broad-spectrum antibody, which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

Catalog Number: 75916-000

Supplier: Biotium

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Description: CD68 Monoclonal antibody, Clone: LAMP4/824, Host: Mouse, Species reactivity: Human, Isotype: IgG2a, kappa, Conjugate: BSA-free, Immunogen: Recom human LAMP4 protein, Synonyms: GP110, LAMP4, Application: IF, IHC, FC, Size: 50 uL

Catalog Number: 75918-766

Supplier: Biotium

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Description: Nuclear Membrane, Monoclonal antibody, Clone: AE-5, Host: Mouse, Species reactivity: Human, Isotype: IgM, kappa, Conjugate: CF488A, Immunogen: Nuclei of myeloid leukemia biopsy cells, Application: Immunofluorescence, Size: 500uL

Catalog Number: 75966-292

Supplier: Biotium

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Description: This antibody recognizes cytokeratin 10 (56.5 kDa) and cytokeratin 13 (53 kDa) in Western blotting. It recognizes only cytokeratin 13 in formalin-fixed, paraffin-embedded tissue sections. It does not react with cytokeratin 10 positive, cytokeratin 13 negative epithelia such as epidermis. However, on frozen sections this MAb serves as differentiation-related marker of all stratified epithelia; it stains all suprabasal cells in both cornifying and non-cornifying stratified epithelia and more differentiated cells of squamous carcinomas.

Catalog Number: 75916-152

Supplier: Biotium

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Description: PMA Enhancer for Gram Negative Bacteria was designed to improve PMA- and PMAxx™-mediated discrimination between live and dead gram-negative bacteria.

Catalog Number: 10154-206

Supplier: Biotium

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Description: This product is prepared by labeling highly cross-adsorbed donkey anti-goat IgG (H+L) with the blue fluorescent dye CF™405M. CF™405M is spectrally similar to and as bright as Pacific Blue® dye but is significantly more photostable than the latter. An additional advantage of CF™405M is that it has less spillover in the 525/50 green channel than Pacific Blue® dye due to narrower emission peak, making CF™405M a superior choice in multi-color detection applications. To minimize cross-reactivity, the antibody has been adsorbed against chicken, guinea pig, Syrian hamster, horse, human, mouse, rabbit, and rat serum proteins.

Pacific Blue® is a registered trademark of Thermo Fisher Scientific.

Catalog Number: 10018-294

Supplier: Biotium

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Description: Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Catalog Number: 75909-252

Supplier: Biotium

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Description: This antibody recognizes a dimer of two proteins of 70 kDa and ~80 kDa, identified as two subunits of Ku. This MAb This antibody recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Catalog Number: 75956-166

Supplier: Biotium

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Description: MHC II (HLA-DQ), Monoclonal antibody, Clone: SPV-L3, Host: Mouse, Species reactivity: Human, Pig, Isotype: IgG2a, kappa, Conjugate: CF640R, Immunogen: T4-positive CTL clone HG-38, Application: Immunofluorescence, Flow cytometry, Size: 100uL

Catalog Number: 75961-094

Supplier: Biotium

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