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Description: Secondary Antibody, Host species: Donkey, Reactivity (target): Mouse igG, Conjugation: HRP, Concentration: 1 mg/mL, Size: 1mg. Cross adsorption: bovine, chicken, goat, guinea pig, horse, human, rabbit, sheep, Syrian hamster.
Catalog Number: 10119-142
Supplier: Biotium


Description: EGFr Monoclonal antibody, Clone: B1D8, Host: Mouse, Species reactivity: Human, Isotype: IgG1, Conjugate: CF405S, Immunogen: Microsomes from A431 cells, Synonyms: Erbb1, ERBB1, Application: FC, Affinity purification, IP, Size: 500 uL
Catalog Number: 75925-412
Supplier: Biotium


Description: This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.
Catalog Number: 75912-388
Supplier: Biotium


Description: This antibody recognizes keratin 5 (58 kDa) and keratin 8 (52.5 kDa). Simple epithelia express cytokeratin 8 in combination with 18. On the other hand, basal cells of stratified epithelia express cytokeratin 5 paired with 14. This antibody therefore, reacts with a wide range of epithelia and their carcinomas.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.
Catalog Number: 75919-922
Supplier: Biotium


Description: CD106 / VCAM1 Monoclonal antibody, Clone: VCAM1/843, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Recom human VCAM1 protein, Synonyms: CD106, INCAM-100, L1CAM, Application: IF, IHC, FC, Size: 100uL
Catalog Number: 75883-470
Supplier: Biotium


Description: Cytokeratin 19 Monoclonal antibody, Clone: A53-B/A2 + BA17, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: CF405S, Immunogen: Human breast cancer MCF-7 cells, Synonyms: k19, k1cs, krt19, Application: IF, Size: 100uL
Catalog Number: 75922-468
Supplier: Biotium


Description: This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Catalog Number: 75912-294
Supplier: Biotium


Description: CD36Monoclonal antibody, Clone: 185-1G2, Host: Mouse, Conjugate: CF405S, Species reactivity: Human, Isotype: IgG2a, kappa, Immunogen: Stimulated human leukocytes, Application: IF, FC, Size: 100uL
Catalog Number: 75894-816
Supplier: Biotium


Description: Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.Immuno-histochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.
Catalog Number: 75920-854
Supplier: Biotium


Description: Protein phosphorylation is a fundamental event in the regulation of a large number of intracellular processes. Phosphorylation of specific tyrosine residues is the result of activation or stimulation of their respective protein tyrosine kinases. The phosphorylated proteins can be auto-phosphorylated kinases or certain cellular protein substrates. Tyrosine-phosphorylated proteins are involved in signal transduction and in the regulation of cell proliferation. Antibody to phosphotyrosine provides an excellent tool for the detection, characterization, and purification of phosphotyrosine containing proteins. This MAb shows no cross-reaction with other phosphoamino acids and is superb for multiple applications including staining of formalin/paraffin tissues.
Catalog Number: 75970-204
Supplier: Biotium


Description: Anti-IgG1 Goat Polyclonal Antibody (CF™ 770)
Catalog Number: 71004-330
Supplier: Biotium


Description: This antibody recognizes a protein of ~55 kDa, identified as SOX10. This MAb is highly specific and does not cross-react with other members of the SOX-family. SOX genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly expressed in desmoplastic melanomas. SOX-10 is considered as a very reliable marker for recognizing residual desmoplastic melanomas. In normal tissues, it is expressed in Schwann cells, melanocytes, and myoepithelial cells of salivary, bronchial and mammary glands. SOX-10 expression is also observed in mast cells.
Catalog Number: 75974-278
Supplier: Biotium


Description: In Western blotting, this antibody recognizes proteins in MW range of 265-400 kDa, identified as different glycoforms of EMA. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinomas. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.
Catalog Number: 75963-710
Supplier: Biotium


Description: CD8a (clone SK1) is a validated mouse monoclonal antibody that recognizes CD8a, a transmembrane glycoprotein and co-receptor found in T cells. This antibody derived from the CD8 alpha chain. The antibody is available conjugated to CF® Dyes and Astral™ tandem dyes. They are supplied in PBS, 0.1% BSA, 0.05% azide.
Catalog Number: 77449-078
Supplier: Biotium


Description: CD71 Monoclonal antibody, Clone: DF1513, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: KG1 acute myeloid leukemia cell line, Synonyms: Mtvr-1, p90, TFR1, Application: IF, WB, FC, Size: 500 uL
Catalog Number: 75918-942
Supplier: Biotium


Description: Cytokeratin 7 Monoclonal antibody, Clone: KRT7/760, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: purified, Immunogen: Recom full-length human KRT7, Synonyms: CK-7, K2C7, Keratin 55K Type II, Application: IF, IHC, Size: 500 uL
Catalog Number: 75921-750
Supplier: Biotium


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