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Catalog Number: (77007-500)
Supplier: Genscript
Description: Pertuzumab (also called 2C4, trade name Perjeta) is a monoclonal antibody used in combination with trastuzumab and docetaxel for the treatment of metastatic HER2-positive breast cancer; it also used in the same combination as a neoadjuvant in early HER2-positive breast cancer. The epitope for pertuzumab is the domain of HER2 where it binds to HER3, and pertuzumab prevents the HER2/HER3 dimer from forming, which blocks signalling by the dimer to prevent HER2 from functioning. Anti-Pertuzumab antibody (11H4), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Pertuzumab.


Catalog Number: (77007-644)
Supplier: Genscript
Description: SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), also known as SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), also known as 2019-nCoV, is a positive-sense single-stranded RNA virus. It caused coronavirus disease in 2019 (COVID-19). SARS-CoV-2 contains glycosylated spike (S) protein, which is composed of S1 subunit and S2 subunit. The S1 contains a receptor-binding domain (RBD) that can bind to ACE2 receptor on target cells.Neutralizing antibodies against SARS-CoV-2 can block the interaction between SARS-CoV-2 RBD and ACE2. The blocking ability of SARS-CoV-2 neutralizing antibodies is affected by its quantity. This standard product is intended for the calibration of SARS-CoV-2 neutralizing antibodies in the materials or samples. It can be used in the assessment and development of assays for the detection and quantitation of SARS-CoV-2 neutralizing antibodies. The neutralizing antibody standard binds to multiple neutralizing epitopes in the receptor-binding domain. This product has been verified to calibrate the quantitative assay of SARS-CoV-2 neutralizing antibody with the Surrogate Virus Neutralization Test (sVNT) (GenScript, Cat.No L00847-A), plaque reduction neutralization test (PRNT) and pseudovirus neutralization test (pVNT) (GenScript, Cat.No SC2087). Users can design assays to detect and evaluate the quantitation of SARS-CoV-2 neutralizing antibodies by this product.


Catalog Number: (76510-680)
Supplier: Genscript
Description: This alpha factor pheromone arrests yeast in the G1 phase of their cell cycle. It helps to induces the expression of mating gene, changes in nuclear architecture and consequently polarizes the growth toward the mating partner.


Catalog Number: (76510-540)
Supplier: Genscript
Description: 36053883


Supplier: Genscript
Description: Genscript ToxinSensorTM Chromogenic LAL Endotoxin Assay Kit is designed to be a quantitative In Vitro end-point endotoxin test for human and animal parenteral drugs, biological products, and medical devices.

SDS

Catalog Number: (10498-120)
Supplier: Genscript
Description: This antibody recognizes NWSHPQFEK tagged fusion protein.


Catalog Number: (89493-824)
Supplier: Genscript
Description: Avi Tag Is A Biotin-Acceptor Peptide, Glndifeaqkiewhe. The 15-Residue Peptide Served As A Substrate Mimic For Biotin Ligase (Bira), Which Usually Recognizes The Much Larger Protein Domain. Avi Tag Is A Useful Tool In Analysis Of Avi Fusion Proteins.


Catalog Number: (77007-534)
Supplier: Genscript
Description: Sarilumab with the trade name of Kevzara, is a human monoclonal IgG1 antibody. It binds to membrane bound and soluble interleukin 6 (IL-6) receptor forms. It was FDA-approved in for the treatment of Rheumatoid Arthritis (RA) in combination with methotrexate. GenScript anti-sarilumab antibody, pAb, rabbit is produced from sera of a rabbit immunized with Sarilumab.


Supplier: Genscript
Description: SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), also known as 2019-nCoV, is a positive-sense single-stranded RNA virus. It caused coronavirus disease in 2019 (COVID-19). SARS-CoV-2 contains glycosylated spike (S) protein, which is composed of S1 subunit and S2 subunit. The S1 contains a receptor-binding domain (RBD) that can bind to ACE2 receptor on target cells. Lineage B.1.351 (a.k.a. 20H/501Y.V2) is a variant of SARS-CoV-2. It has multiple mutations in the RBD, including K417N, E484K, N501Y. Lineage B.1.1.7 (a.k.a. 20I/501Y.V1) is also a variant of SARS-CoV-2 and has a mutation called N501Y in the RBD.SARS-CoV-2 Spike (E484) Neutralizing Antibody (COV2109) is produced from cell culture <i>in vitro</i> under conditions free from animal-derived components. The product is a humanized neutralizing antibody, recognizing E484 site of wild-type RBD. When E484 is mutated to E484K, the mutant RBD, such as RBD (B.1.351) as seen in Figure 1, can’t be recognized by the product.

Catalog Number: (10500-528)
Supplier: Genscript
Description: This antibody recognizes c-Myc tagged fusion proteins.


Supplier: Genscript
Description: The product is specific for SARS-CoV-2 spike protein S1 subunit and its RBD domain.

Supplier: Genscript
Description: The product is specific for SARS-CoV-2 spike protein S1 subunit and its RBD domain.

Catalog Number: (77007-512)
Supplier: Genscript
Description: Omalizumab with trade name Xolair, is an FDA-approved drug for the treatment of moderate to severe persistent asthma in adults and adolescents (12 years of age and above). It is a recombinant humanized monoclonal antibody. It selectively binds to human immunoglobulin E (IgE). Omalizumab inhibits the binding of IgE to the high-affinity IgE receptor (FcεRI) on the surface of mast cells and basophils. Anti-Omalizumab antibody (15B12), mAb, mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with omalizumab.


Catalog Number: (10498-210)
Supplier: Genscript
Description: The antibody is specific for proteins containing phosphotyrosine residues and phosphotyrosine peptides. It does not cross-react with phosphoserine, phosphothreonine or nonphosphorylated tyrosine residues.


Catalog Number: (76509-896)
Supplier: Genscript
Description: The product is specific for Obinutuzumab. This antibody serves as an excellent positive control for Obinutuzumab immunogenicity (ADA) assays.


Catalog Number: (10498-188)
Supplier: Genscript
Description: THE™ V5 tag antibody [iFluor 488], mAb, mouse recognizes N-terminal, internal and C-terminal V5-tagged proteins.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • State issued document with your organization's Federal Tax ID Number
  • State issued document with your organization's Resale Tax ID Number
  • City or County issued Business License
  • State Department of Health Services License
  • Any other ID issued by the State that includes the business name and address

* Please note if your account is within the State of California two of these pieces of identification will be required.
VWR will not lift restrictions for residential shipping addresses.

-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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