You Searched For: VIKAN NORTH AMERICA CORPORATION

Supplier: Genscript

Description: Vascular endothelial growth factor (VEGF) is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, Vascular endothelial growth factor (VEGF) plays a prominent role in normal and pathological angiogenesis.

Catalog Number: (89495-088)

Supplier: Genscript

Description: THE™ His Tag antibody [HRP], mAb, Mouse recognizes His tags localized at C-terminal, N-terminal and internal region of fusion proteins

Sale

Catalog Number: (89495-084)

Supplier: Genscript

Description: GenScript THE™ HA Tag antibody [FITC], mAb, Mouse recognizes C-terminal, N-terminal and internal HA tagged fusion proteins.

Sale

Catalog Number: (89495-086)

Supplier: Genscript

Description: GenScript THE™ His Tag antibody [FITC], mAb, Mouserecognizes C-terminal, N-terminal and internal His tagged fusion proteins.

Sale

Catalog Number: (89493-644)

Supplier: Genscript

Description: THE™ DYKDDDDK Tag antibody [Biotin], mAb, Mouse recognizes C-terminal, N-terminal and internal tagged fusion proteins.

Sale

Supplier: Genscript

Description: SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), also known as 2019-nCoV, is a positive-sense single-stranded RNA virus. It caused coronavirus disease in 2019 (COVID-19). SARS-CoV-2 contains glycosylated spike (S) protein, which is composed of S1 subunit and S2 subunit. The S1 contains a receptor-binding domain (RBD) that can bind to ACE2 receptor on target cells. Lineage B.1.351 (a.k.a. 20H/501Y.V2) is a variant of SARS-CoV-2. It has multiple mutations in the RBD, including K417N, E484K, N501Y. Lineage B.1.1.7 (a.k.a. 20I/501Y.V1) is also a variant of SARS-CoV-2 and has a mutation called N501Y in the RBD.SARS-CoV-2 Spike (N501) neutralizing antibody (COV2110) is produced from cell culture <i>in vitro</i> under conditions free from animal-derived components. The product is a humanized neutralizing antibody, recognizing N501 site of wild-type RBD. When N501 is mutated to N501Y, the mutant RBD, such as RBD (B.1.1.7) and RBD (B.1.351) as seen in Figure 1, can't be recognized by the product.

Catalog Number: (77007-650)

Supplier: Genscript

Description: Payloads are the important components of antibody-drug conjugates (ADCs). The most commonly used ADC payloads are MMAE, DM1, and DXd. ADC pharmacokinetic (PK) studies include free payload analysis, conjugated antibody analysis, and total antibody analysis via ligand-binding assay (LBA) and LC-MS/MS assay. The anti-payload antibody is a useful reagent in PK assay for determining conjugated antibodies. It can be used as a capture antibody to determine the conjugated antibody in LBA assay or through immunocapture to enrich the ADC sample in LC-MS/MS assay. The DXd, also known as exatecan derivative, is a potent inhibitor of DNA topoisomerase I. Trastuzumab deruxtecan (T-DXd, DS-8201a or Enhertu®), composed of trastuzumab conjugated to DXd, is the first approved ADC for the treatment of breast cancer.

Sale

Catalog Number: (76510-044)

Supplier: Genscript

Description: GenScript’s MonoRab™ Rabbit Anti-Camelid VHH Cocktail is specific for Camelid VHH antibody (Llama, Alpaca, and Camel). It has no cross-reactivity with mouse, rat, rabbit, goat or human immunoglobulins.

Sale

Catalog Number: (77007-614)

Supplier: Genscript

Description: Panitumumab with trade name Vectibix, is an FDA-approved drug for the treatment of patients with EGFR-expressing metastatic colorectal carcinoma with non-mutated (wild-type) KRAS after failure of fluoropyrimidine-, oxaliplatin- and irinotecan-containing chemotherapy regimens. It is a human monoclonal antibody. Panitumumab binds to the human EGF receptor (EGFR), preventing binding of activating ligands, such as the EGF and transforming growth factor alpha. GenScript anti-panitumumab antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Panitumumab.

Sale

Catalog Number: (76509-994)

Supplier: Genscript

Description: The antibody is recommended as detection antibody in a pharmacokinetic (PK) bridging assay with captrue antibody GenScript, A01984-40, MonoRab anti-atezolizumab antibody (55D8), mAb, rabbit.

Sale

Catalog Number: (76510-058)

Supplier: Genscript

Description: GenScript MonoRab™ Rabbit Anti-Camelid VHH Cocktail [iFluor 488] is specific for Camelid VHH antibody (Llama, Alpaca and Camel). It has no cross-reactivity with mouse, rat, rabbit, goat or human immunoglobulins.

Sale

Catalog Number: (77007-610)

Supplier: Genscript

Description: A camelid single-domain antibody (sdAb, called Nanobody by Ablynx) is a peptide chain about 110 amino acids long comprising one variable domain of a heavy-chain antibody (VHH fragment). Like a whole antibody, a single-domain antibody is able to bind selectively to a specific antigen. Such antibodies allow a broad range of applications in biotechnical as well as therapeutic fields due to their small size, simple production, and high affinity. However, their sequences may increase the risk of immunogenicity and cause anti-drug antibody (ADA) development in humans, and thus, sdAbs are routinely humanized during development.

Sale

Catalog Number: (76509-916)

Supplier: Genscript

Description: The product is specific for Rituximab. The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody GenScript, A01942-40, MonoRab™ Anti-Rituximab Antibody (137C6), mAb, Rabbit.

Sale

Catalog Number: (76509-954)

Supplier: Genscript

Description: MonoRab™ HA tag antibody recognizes HA tags placed at N-terminal, C-terminal, and internal regions of fusion proteins.

Sale

Catalog Number: (77007-576)

Supplier: Genscript

Description: Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. It regulates the cellular uptake, utilization, and storage of glucose, amino acids, and fatty acids and inhibits the breakdown of glycogen, protein, and fat. Proinsulin is the prohormone precursor to insulin made in pancreas. It is processed by a series of proteases to form mature insulin. Mature insulin has 35 fewer amino acids; 4 are removed altogether, and the remaining 31 form the C-Peptide. The C-Peptide is abstracted from the center of the proinsulin sequence; the two other ends (alpha and β chains) remain connected by disulfide bonds. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma. GenScript Insulin Antibody (6E9F1), mAb, Mouse is produced from the hybridoma resulting from fusion of SP2/0-Ag14 myeloma and B-lymphocytes obtained from mouse immunized with human recombinant Insulin expressed in yeast.

Sale

Catalog Number: (76198-728)

Supplier: Genscript

Description: This antibody recognizes strep-tag II tagged fusion proteins.

Sale