You Searched For: Antibodies

Catalog Number: (RL612-1107)

Supplier: Rockland Immunochemical

Description: Anti-Rat IgM (mu chain) (GOAT) Antibody has been assayed against Rat IgM in a standard capture ELISA using Peroxidase Conjugated Streptavidin. A working dilution of 1:15,000 to 1:70,000 of the concentration is suggested for this product.

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Catalog Number: (10802-046)

Supplier: Rockland Immunochemical

Description: Beclin-1 antibody detects human Beclin-1. Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. Beclin-1, a coiled-coil Bcl-2-interacting protein homologous to the yeast autophagy gene apg6, is a mammalian autophagy gene that can inhibit tumorigenesis and is expressed at reduced levels in human breast carcinoma, suggesting that defects in autophagy proteins may contribute to the development or progression of tumors. Bcl-2 can bind to Beclin-1 and inhibit Beclin-1-dependent autophagy in yeast and mammalian cells, suggesting that Bcl-2 functions as an anti-autophagy protein as well as an anti-apoptotic protein, which helps maintain autophagy at levels that are more compatible with cell survival rather than cell death. Anti-Beclin-1 antibodies are ideal for investigators involved in apoptosis and cancer research.

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Catalog Number: (10151-758)

Supplier: Immunoreagents

Description: The ImmunoReagents' DyLight® 633 conjugates fluoresces red with physical properties comparable to other 633 dyes. DyLight® 633 is ideal for multi-color applications. DyLight® 633 is available as reactive labeling agents and as conjugates of secondary antibodies and biotin-binding proteins for use in fluorescence microscopy, flow cytometry, Western blotting, ELISA, high-content screening and other array platforms. Excitation/Emission = 638nm / 658nm Emission Color = Red (Similar Dyes: Alexa Fluor 633)

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Catalog Number: (75933-840)

Supplier: Rockland Immunochemical

Description: LYRM3, also known as NADH dehydrogenase (ubiquinone) 1 beta subcomplex 9 (NDUFB9), is a ubiquitously expressed LYR-motif containing protein. It has been suggested to be a candidate gene for the branchio-oto-renal (BOR) syndrome, which is characterized by branchial and renal abnormalities and heredity deafness disorders. Other than its LYR-motif, LYRM3 appears to have no functional or structural relationship to either LYRM1 or LYRM2.

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Catalog Number: (75930-338)

Supplier: Rockland Immunochemical

Description: Neuroligin-1 is a neuronal cell surface protein belonging to the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of excitatory synapses for their normal, functional development, and is necessary to the regulation of synaptic plasticity and the development of long-term memory within the adult amygdala in mammals. It is believed to participate in cell-cell-interaction through the assembly of intracellular junction by the binding of beta-neurexins, and may also be a factor in the maintenance and assembly of synaptic junctions. It is also thought to have involvement in excitatory synaptic specification. Within brain tissue, Neuroligin-1 is primarily observed in neurons and spinal cord. Anti-Neuroligin-1 is ideal for research in Neuroscience, including narcolepsy and synaptic neurotransmission: GABAergic inhibition, as well as Cell Adhesion.

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Catalog Number: (RL200-301-964S)

Supplier: Rockland Immunochemical

Description: Anti-PDCD4 Mouse Monoclonal Antibody [clone: 9G6]

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Catalog Number: (10802-660)

Supplier: Rockland Immunochemical

Description: F(ab')2 Bovine IgG (H&L), Polyclonal antibody, Host: Rabbit, Target Species: Bovine, Format: IgG F(ab')2, Immunogen: Bovine IgG whole molecule, Applications: immunomicroscopy and flow cytometry or FACS analysis, antibody based fluorescent assays, Size: 20mg

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Catalog Number: (10802-078)

Supplier: Rockland Immunochemical

Description: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1b and IL-18. Caspase-4 was initially identified as a homologous protein to Caspase-1 and the C. elegans Ced-3 which could induce apoptosis in transfected cells. More recent studies have shown that it can be activated by ER stress and has been suggested to be involved in multiple neuronal pathologies such as Alzheimer's disease.

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Catalog Number: (76262-898)

Supplier: Rockland Immunochemical

Description: ERK2 antibodies detect the ERK2 isoform. Mitogen activiated protein kinase 1, also known as MAPK1, ERK, or ERK2, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. ERK1 and ERK2 are activated by MEK1 and MEK2 in the B-raf signaling pathway resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Human ERK1 and ERK2 are 84% identical in sequence and share common functionality in cells. Anti-ERK2 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.

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Catalog Number: (RL600-403-B09)

Supplier: Rockland Immunochemical

Description: 100ug. Polyclonal. Immunogen: synthetic peptide corresponding to a region near the amino terminal end of human NAG-1 protein. A residue of cysteine was added to facilitate coupling to KLH. Reactivity: human

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Catalog Number: (76234-916)

Supplier: Rockland Immunochemical

Description: MEK2 antibodies detect the MEK2 isoform. Mitogen-activated protein kinase kinase 2, also known as MEK2 or MKK2, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. This pathway also plays a key role in synaptic plasticity in the brain. Activated MEK 2 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase. MEK1 and MEK2 are about 80% identical to each other, and nearly identical within the kinase domain. The MEK2 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.

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Catalog Number: (76262-824)

Supplier: Rockland Immunochemical

Description: MEK2 antibodies detect the MEK2 isoform. Mitogen-activated protein kinase kinase 2, also known as MEK2 or MKK2, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. This pathway also plays a key role in synaptic plasticity in the brain. Activated MEK 2 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase. MEK1 and MEK2 are about 80% identical to each other, and nearly identical within the kinase domain. The MEK2 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.

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Catalog Number: (76262-908)

Supplier: Rockland Immunochemical

Description: MEK2 antibodies detect the MEK2 isoform. Mitogen-activated protein kinase kinase 2, also known as MEK2 or MKK2, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. This pathway also plays a key role in synaptic plasticity in the brain. Activated MEK 2 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase. MEK1 and MEK2 are about 80% identical to each other, and nearly identical within the kinase domain. The MEK2 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.

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Catalog Number: (RL200-306-I51)

Supplier: Rockland Immunochemical

Description: Anti-AKT3 BIOTIN Antibody is suitable for Flow Cytometry, ELISA, immunochemistry, and western blotting. Expect a band approximately 56 kDa in size corresponding to AKT3 Protein by western blotting in the appropriate cell lysate or extract.

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Catalog Number: (RL201032320100)

Supplier: Rockland Immunochemical

Description: Polyclonal antibody, Host:Goat, Species reactivity:Bovine, Label:Peroxidase (Horseradish), Immunogen:Acetylcholinesterase [Bovine Erythrocytes], Application:ELISA, Western Blot, ImmunoPrecipitation

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Catalog Number: (75934-904)

Supplier: Rockland Immunochemical

Description: Isotype controls are important for Flow Cytometry and have no specificity for target cells within a particular experiment. Their purpose is to confirm the specificity of primary antibody binding that it is not a result of non-specific Fc receptor binding to cells or other cellular protein interactions. Isotype controls need to be matched to the specific primary Abs (species and isotype, including heavy and light chains) being used.

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