You Searched For: VANBERGEN

Description: ImmunoReagents’ FITC Conjugates are used in immunofluorescence microscopy, flow cytometry, FLISA (fluorescent ELISA) and high throughput screening assays. Fluorescein is typically excited by the 488 nm line of an argon laser, and emission is collected at 518 nm. FITC antibody conjugates are yellow-orange in color but emit a yellow-green color upon Em 518 nm. FITC antibody conjugates are sensitive to light. The typical FITC to antibody ratio (F/P) is >4.0 Excitation/Emission = 494nm / 518nm Emission Color = Green (Similar Dyes: Alexa Fluor 488, Cy2, DyLight ® 488)

Catalog Number: 10151-232

Supplier: Immunoreagents

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Description: Recombinant monclonal antibody (Mouse IgG2aλ).

Recommended Applications: Flow Cytometry, WB

Catalog Number: 76284-720

Supplier: Enzo Life Sciences

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Description: The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding. Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding. The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility. Much less is known about the second group, which includes PAK4, 5 and 6. These proteins are not activated by Cdc42/Rac binding. PAK5 was initially identified as a kinase expressed primarily in brain that while possessing a kinase domain and GTPase binding domain similar to PAK4 and PAK6, is completely different from both. Expression of PAK5 in neural based cell lines resulted in neurite outgrowth suggesting that PAK5 may be involved in regulating the cytoskeletal changes necessary for promoting neurite outgrowth. Other experiments suggest that unlike the other PAKs, PAK5 may inhibit apoptosis by phosphorylating the Bcl-2 family member Bad.

Catalog Number: 75935-516

Supplier: Rockland Immunochemical

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Description: Anti-Parkin pS378 Antibody is suitable for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximatley 52 kDa in size corresponding to parkin Protein phosphorylated at Ser378 .

Catalog Number: RL609-401-E07

Supplier: Rockland Immunochemical

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Description: ImmunoReagents’ FITC Conjugates are used in immunofluorescence microscopy, flow cytometry, FLISA (fluorescent ELISA) and high throughput screening assays. Fluorescein is typically excited by the 488 nm line of an argon laser, and emission is collected at 518 nm. FITC antibody conjugates are yellow-orange in color but emit a yellow-green color upon Em 518 nm. FITC antibody conjugates are sensitive to light. The typical FITC to antibody ratio (F/P) is >4.0 Excitation/Emission = 494nm / 518nm Emission Color = Green (Similar Dyes: Alexa Fluor 488, Cy2, DyLight ® 488)

Catalog Number: 10150-378

Supplier: Immunoreagents

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Description: Host: Mouse, Isotype: IgG1 kappa

Catalog Number: 89153-916

Supplier: Enzo Life Sciences

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Description: Voltage-dependent anion-selective channel protein 1 (also known as VDAC, VDAC1 or outer mitochondrial membrane protein porin 1) is the the outer mitochondrial membrane receptor for hexokinase and BCL2L1. VDAC forms a channel through the mitochondrial membrane and is involved in small molecule diffusion, cell volume regulation and apoptosis. VDAC may participate in the formation of the permeability transition pore complex (PTPC), which is responsible for the release of mitochondrial products that triggers apoptosis. Anti-VDAC1 is ideal for research in Cell Biology and Apoptosis.

Catalog Number: 75933-542

Supplier: Rockland Immunochemical

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Description: Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A). TCTEX1D3, also called TCTE3, has been identified as a gene responsible for congenital diaphragmatic hernia (CDH).

Catalog Number: 75932-788

Supplier: Rockland Immunochemical

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Description: Produced through a multi-stage process that includes delipidation, salt fractionation, ion-exchange chromatography, gel filtration, and affinity chromatography. No contaminating proteins are observed when assayed at a protein concentration of 20mg/mL against anti-whole serum or anti-fragment specific antisera. All immunoglobulin fragments are prepared from highly purified, whole molecules subject to enzymatic digestion.

Catalog Number: RL004-0304

Supplier: Rockland Immunochemical

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Description: Recombinant monclonal antibody (Rabbit IgGκ).

Recommended Applications: Flow Cytometry

Catalog Number: 76284-960

Supplier: Enzo Life Sciences

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Catalog Number: RL200601143010

Supplier: Rockland Immunochemical

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Description: The telomeric repeat binding factor family (TERF1 and TERF2) plays a key role in cellular immortalization and cellular senescence (1). TERF2, as a component of the telomere nucleoprotein complex, is present at telomeres in metaphase of the cell cycle (2). TERF2 is a second negative regulator of telomere length and binds as a dimer to TTAGGG repeats at ends of chromosomes (telomeres), where it blocks inappropriate activation of the ATM/p53 pathway (2,3). TERF1 negatively regulates telomere elongation, while TERF2 protects the chromosome ends by inhibiting end-to-end fusions. Down-regulation of TRF expression in tumor cells may contribute to cell immortalization and malignant progression (4,5).

Catalog Number: 75932-824

Supplier: Rockland Immunochemical

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Description: MeCP2 (Methyl-CpG Binding Protein 2) is a chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair and is not influenced by sequences flanking the methyl-CpGs. MeCP2 has been shown to mediate transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Defects in MeCP2 are the cause of Rett syndrome (RTT). RTT is an X-linked dominant disease; it is a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. Recent studies have reported a new phosphorylation site at Ser421. Phosphorylation and dephosphorylation of this site may be involved in regulation of behavioral responses to chronic antidepressant treatment. MeCP2 pS421 Antibody is ideal for researchers interested in neuroscience research.

Catalog Number: 75929-924

Supplier: Rockland Immunochemical

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Description: D-Amino Acid Oxidase [Pig Kidney] in a standard capture ELISA using ABTS as a substrate for 30 minutes at room temperature

Catalog Number: RL206031430100

Supplier: Rockland Immunochemical

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Description: Secondary Rabbit Anti-IgG (H&L) Reacts with Rat

Catalog Number: RL712-409-002

Supplier: Rockland Immunochemical

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Description: Polyclonal antibody, Host:Goat, Species reactivity:Lactococcus lacti, Label:Peroxidase (Horseradish), Immunogen:Beta Phosphoglucomutase [Lactococcus lacti], Application:ELISA, Western Blot

Catalog Number: RL201032370100

Supplier: Rockland Immunochemical

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