You Searched For: Antibodies

Catalog Number: (75930-942)

Supplier: Rockland Immunochemical

Description: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 pathway, including Chk2, p53R2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. The transcriptional activity of p53 is modulated by protein stability and acetylation. PID/MTA2, also termed MTA1-L1, was found to be a subunit of nucleosome remodeling and deacetylating (NRD/NuRD) complex. PID/MTA2 modulates the enzymatic activity of the histone deacetylase complex and its expression reduces the levels of acetylated p53. Deacetylation of p53 by PID/MTA2 represses p53-dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis. PID/MTA2 is ubiquitously expressed in human tissues.

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Catalog Number: (RL609-109-123)

Supplier: Rockland Immunochemical

Description: Secondary Goat Anti-IgG (H&L) Reacts with Human

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Catalog Number: (76002-150)

Supplier: Enzo Life Sciences

Description: Recommended Applications: ELISA, Flow Cytometry, ICC, IF, IHC, IHC (FS), IHC (PS), IP, WB

Species reactivity: Human, Mouse, Rat, Sheep, Rabbit, Porcine, Monkey, Ferret, Bovine

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Catalog Number: (76284-754)

Supplier: Enzo Life Sciences

Description: Recombinant monclonal antibody (Rabbit IgGκ).

Recommended Applications: Flow Cytometry, IF

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Catalog Number: (10151-244)

Supplier: Immunoreagents

Description: ImmunoReagents’ Biotinylated antibody conjugates are widely used due to their ability to enhance antibody signal in most immunoassays. Biotinylated secondary antibodies are used in most immunoassay formats (i.e., ELISA, Immunohistochemistry (IHC), and Western blotting). While Biotinylated antibodies by themselves do not produce a signal that can be visualized, biotin has a high affinity and specificity to Streptavidin/Avidin. Using ImmunoReagents’ streptavidin conjugates with biotinylated antibodies results in signal amplification.

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Catalog Number: (10151-252)

Supplier: Immunoreagents

Description: The ImmunoReagents' DyLight® 350 conjugates are a derivative of AMCA (Aminomethylcoumarine acetate), which a blue fluorescent dye commonly is used as a contrasting dye for double- and triple-labeling used in a wide array of applications. The UV-excitable DyLight® 350 has spectral properties that are very similar to those displayed by AMCA, including identical excitation wavelengths and a large stokes shift. The emission wavelength of DyLight® 350 has a 10-nm blue shift over AMCA, though, that provides an advantage in multiplexing with green fluorophores. (Excitation/Emission = 353nm / 432nm Emission Color = Blue (Similar Dyes: Alexa Fluor 350, AMCA)

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Catalog Number: (10802-070)

Supplier: Rockland Immunochemical

Description: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. BOK, a pro-apoptotic Bcl-2 family member, was initially identified in the ovary, and was found to interact with other Bcl-2 family members such as Mcl-1 and Bfl-1. BOK expression is high during early placental development, suggesting that it may also play a role in regulating trophoblast cell proliferation.

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Catalog Number: (10802-600)

Supplier: Rockland Immunochemical

Description: Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 7 (ELOVL7) is a member of fatty acyl-CoA elongase gene family that elongates saturated very-long-chain fatty acids (SVLFA, C20:0-) and has been suggested to be involved in prostate cancer growth through saturated long-chain fatty acid metabolism. The metabolic pathways of long-chain fatty acids play an important role in the maintenance of membrane lipid composition and the generation of cell signaling precursor molecules such as eicosanoids and sphingosine-1 phosphate. Overexpression of ELOVL7 results in lipid accumulation in differentiated adipocytes; its expression is regulated by the microRNA miR-219.

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Catalog Number: (RL610-156-043)

Supplier: Rockland Immunochemical

Description: Anti-Mouse IgG3 secondary antibody is suitable for ELISA.

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Catalog Number: (RL610-155-041)

Supplier: Rockland Immunochemical

Description: Anti-Mouse IgG2a secondary antibody is suitable for ELISA.

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Catalog Number: (RL200-4297-01)

Supplier: Rockland Immunochemical

Description: Polyclonal, Host: Rabbit, Conjugate: Fluorescein, Isotype: IgG, Application: FLISA, FlowCytometry, Western Blot, Synonyms: FITC, Avidin Fluorescein, Anti-Avidin FITC Antibody, 100UG

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Catalog Number: (76634-322)

Supplier: Diagnostic Biosystems

Description: This antibody is specific to macrophages in a wide variety of human tissues. It reacts with myeloid precursors and peripheral blood granulocytes. It also stains a cell population known as plasmacytoid T cells.

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Catalog Number: (RL200301E64)

Supplier: Rockland Immunochemical

Description: BIN-3 encodes an evolutionarily conserved and ubiquitously expressed member of the BAR superfamily of curved membrane and GTPase-binding proteins implicated in signal transduction and vesicular trafficking.

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Catalog Number: (10802-706)

Supplier: Rockland Immunochemical

Description: F(ab')2 Rat IgG (H&L), Polyclonal antibody, Host: Rabbit, Target Species: Rat, Format: IgG F(ab')2, Label: Fluorescein (FITC), Immunogen: Rat IgG whole molecule, Synonyms: FITC, Application: immunomicroscopy and flow cytometry or FACS, antibody based fluorescent assays, Size: 20mg

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Catalog Number: (RL612-112-120)

Supplier: Rockland Immunochemical

Description: Secondary Goat Anti-IgG (H&L) Reacts with Rat

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Catalog Number: (RL010-0203)

Supplier: Rockland Immunochemical

Description: Produced through a multi-stage process that includes delipidation, salt fractionation, ion-exchange chromatography, gel filtration, and affinity chromatography. No contaminating proteins are observed when assayed at a protein concentration of 20mg/mL against anti-whole serum or anti-fragment specific antisera. All immunoglobulin fragments are prepared from highly purified, whole molecules subject to enzymatic digestion.

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