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Catalog Number: (10266-930)
Supplier: Bioss
Description: Members of the WD repeat protein family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis and gene regulation. BRWD3 (bromodomain and WD repeat-containing protein 3) is a 1,802 amino acid protein expressed in fetal liver and most adult tissues. Existing as five alternatively spliced isoforms, BRWD3 contains two bromo domains, nine WD repeats and is thought to play a role in transcription by modifying chromatin. Mutations in the gene encoding BRWD3 are the cause of mental retardation X-linked type 93 (MRX93), which is also known as mental retardation X-linked with macrocephaly (XLMR). MRX93 is characterized by mild intellectual disability, macrocephaly, a prominent forehead and large cupped ears.


Catalog Number: (89515-862)
Supplier: Abgent
Description: polyclonal antibody Isotype: Rabbit Ig, Species Reactivity: human, Gene ID: 8738, Target/specificity: This CRADD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the Central region of human CRADD.


Supplier: Martor
Description: Replacement blade for Maxisafe cutter (61200-302). Thickness: 0.63mm.

Catalog Number: (10263-864)
Supplier: Bioss
Description: Members of the WD repeat protein family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis and gene regulation. BRWD3 (bromodomain and WD repeat-containing protein 3) is a 1,802 amino acid protein expressed in fetal liver and most adult tissues. Existing as five alternatively spliced isoforms, BRWD3 contains two bromo domains, nine WD repeats and is thought to play a role in transcription by modifying chromatin. Mutations in the gene encoding BRWD3 are the cause of mental retardation X-linked type 93 (MRX93), which is also known as mental retardation X-linked with macrocephaly (XLMR). MRX93 is characterized by mild intellectual disability, macrocephaly, a prominent forehead and large cupped ears.


Catalog Number: (10271-978)
Supplier: Bioss
Description: Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B (By similarity). The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A.


Catalog Number: (10397-632)
Supplier: Bioss
Description: Probable E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3' cleavage.


Catalog Number: (90000-590)
Supplier: BD
Description: High-grade agar specially processed for microbiological purposes that is routinely used as a solidifying agent in microbiological media.

Catalog Number: (470004-516)
Supplier: American 3B Scientific
Description: This deluxe brain comes with opened head to allow detailed study of the brain's position in the skull. The human head is horizontally divided above the skull base. This medially divided deluxe brain model shows the brain arteries in detail and the basilar artery is removable.


Catalog Number: (76188-074)
Supplier: DuPont
Description: Tychem® 10000 exhibits excellent chemical barrier properties and offers an extremely durable fabric that is puncture- and tear-resistant.


Catalog Number: (76629-600)
Supplier: Prosci
Description: Anti-Cd8a Recombinant Antibody [Clone: YTS 169.4]


Catalog Number: (76482-950)
Supplier: AAT BIOQUEST INC
Description: Detecting and quantitating small amounts of RNA is extremely important for a wide variety of molecular biology procedures such as measuring yields of in vitro transcribed RNA and measuring RNA concentrations before performing Northern blot analysis, S1 nuclease assays, RNase protection assays, cDNA library preparation, reverse transcription PCR, and differential display PCR.

Small Business Enterprise Minority or Woman-Owned Business Enterprise


Catalog Number: (89364-846)
Supplier: Genetex
Description: Mouse monoclonal antibody to human Ku80


Supplier: Bio X Cell
Description: InVivoPlus anti-mouse CD8α, Clone: YTS169.4, Isotype: rat IgG2b, κ, Applications: in vivo CD8+ T cell depletion

Catalog Number: (61200-326)
Supplier: Martor
Description: Replacement 0.10mm blade for Folex Cutter (61200-326).


Catalog Number: (470121-246)
Supplier: Wards
Description: This Bridge Rectifier is a must for current studies.


Catalog Number: (10263-872)
Supplier: Bioss
Description: Members of the WD repeat protein family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis and gene regulation. BRWD3 (bromodomain and WD repeat-containing protein 3) is a 1,802 amino acid protein expressed in fetal liver and most adult tissues. Existing as five alternatively spliced isoforms, BRWD3 contains two bromo domains, nine WD repeats and is thought to play a role in transcription by modifying chromatin. Mutations in the gene encoding BRWD3 are the cause of mental retardation X-linked type 93 (MRX93), which is also known as mental retardation X-linked with macrocephaly (XLMR). MRX93 is characterized by mild intellectual disability, macrocephaly, a prominent forehead and large cupped ears.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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