You Searched For: HOBART FOSTER BELGIUM

Description: Recommended Applications: ELISA, ICC, IHC, WB

Species reactivity: Human, Xenopus, Mammalian, Chicken

Catalog Number: 76002-798

Supplier: Enzo Life Sciences

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Description: Host: Mouse, Isotype: IgG1

Catalog Number: 89153-160

Supplier: Enzo Life Sciences

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Description: Anti-inflammatory agent and protein kinase C inhibitor.

Catalog Number: 76002-966

Supplier: Enzo Life Sciences

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Description: Produced in E. coli.

Catalog Number: 89165-310

Supplier: Enzo Life Sciences

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Description: The actions of the octapeptide circulatory hormone angiotensin II are mediated by type one (AT1) and type two (AT2) angiotensin II receptors, members of the seven-transmembrane domain-containing GPCR family. AT1 expression is greatest in vascular smooth muscle, liver, kidney, adrenal cortex, brain, and lung, and is primarily responsible for the physiological effects of angiotensin II in cardiovascular homeostasis. The AT2 receptor displays approximately 30% identity to the AT1 receptor, and is highly expressed during embryonic development. AT2 expression in adult tissue is limited to the adrenal medulla, brain, and reproductive tissues, but is upregulated in injured tissue following myocardial infarction, vascular injury, and wound healing.

Catalog Number: 10050-320

Supplier: Enzo Life Sciences

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Description: TLR4 activator.

Catalog Number: 89152-776

Supplier: Enzo Life Sciences

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Description: Isolated from bovine brain.

Catalog Number: 89145-060

Supplier: Enzo Life Sciences

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Description: Highly reproducible SA-β-gal activity kit

Catalog Number: 76003-296

Supplier: Enzo Life Sciences

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Description: Na+/K+ ATPase inhibitor

Catalog Number: 89149-410

Supplier: Enzo Life Sciences

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Description: Fluorogenic substrate for methionine aminopeptidase 2 (MetAP2) (kcat/Km=1.1 x 10 M-1min-1; Km=310 µM) or aminopeptidase N (Km=377 µM). Ex.: 380 nm, Em.: 460 nm, although the following Ex/Em can also be used: 355,375/440,450. This substrate is useful for inhibitor screening and kinetic analysis. Also available: fluorogenic calibration standard AMC (BML-KI144).

Catalog Number: 89161-128

Supplier: Enzo Life Sciences

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Description: Recombinant monclonal antibody (Mouse F(ab)2).

Recommended Applications: IF, IHC (FS), IHC (PS), IP, WB

Catalog Number: 76284-784

Supplier: Enzo Life Sciences

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Description: Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (HERP) is a membrane-associated ER protein strongly up-regulated by inducers of ER stress.

Catalog Number: 89162-412

Supplier: Enzo Life Sciences

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Description: EGFR substrate

Catalog Number: 89161-208

Supplier: Enzo Life Sciences

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Description: Glucose-regulated protein 94 (Grp94, gp96), an abundant resident endoplasmic reticulum (ER) lumenal stress protein, belongs to the Hsp90 family of molecular chaperones along with cytosolic Hsp90. Grp94 and such other resident soluble proteins of the ER as the Ca 2+ binding protein subfamily (CaBP, CaBPI, CaBP2 and calreticulin) possess the C-terminal tetrapeptide Lys-Asp-Glu-Leu (KDEL), a sorting signal considered responsible for the retention of these proteins in the pre-Golgi compartments. Stress conditions such as glucose starvation and heat shock which promote protein misfolding or unfolding increase Grp94 expression. In addition to a homeostatic role in protein folding and assembly, Grp94 can function in the intracellular trafficking of peptides from the extracellular space to the MHC class I antigen processing pathway of antigen presentation cells. Grp94 and Hsp90 share high sequence identity and apparently identical adenosine nucleotide dependent modes of regulation, although previous data suggests that Hsp90 and Grp94 may differ in their nucleotide binding properties. The N-terminal domain of eukaryotic Hsp90 proteins contains a conserved adenosine nucleotide binding pocket which also serves as the binding site for the Hsp90 inhibitors geldanamycin and radicicol. However, the molecular basis for adenosine nucleotide-dependent regulation of Grp94 remains unclear. Data supports a ligand dependent regulation of Grp94 function, and suggests a model whereby Grp94 function is regulated through a ligand -dependent conversion of Grp94 from an inactive to an active conformation.

Catalog Number: 95043-776

Supplier: Enzo Life Sciences

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Description: Host: Mouse, Isotype: IgG2b

Catalog Number: 89161-992

Supplier: Enzo Life Sciences

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Description: Produced in HEK 293 cells. The cysteine-rich domain of human NGFR (nerve growth factor receptor; p75NTR) (aa 1-250) is fused to the Fc portion of human IgG1.

Catalog Number: 89151-772

Supplier: Enzo Life Sciences

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