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Description: Eukaryotic histones are basic and water-soluble nuclear proteins. They form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.
Catalog Number: 75950-684
Supplier: Biotium


Description: LMBR1 is a 490 amino acid multi-pass membrane protein that is widely expressed with strongest expression in heart and pancreas. Belonging to the LIMR family, LMBR1 shares 95% sequence identity with the mouse protein and may play crucial role in the evolution of limb and skeletal system. LMBR1 is critical for expression of sonic hedgehog (Shh) in the developing posterior limb bud mesenchyme. Mutations in the gene encoding LMBR1 is the cause of several rare conditions such as acheiropody (ACHP) and syndactyly type 4 (SDYT4). ACHP is an autosomal recessive inherited disorder characterized by bilateral congenital amputations of the hands and feet. LMBR1L (limb region 1 protein homolog-like), also known as LIMR (Lipocalin-1-interacting membrane receptor), is a 489 amino acid multi-pass membrane protein that is thought to act as a receptor for Lipocalin-1 and may also assist in its endocytosis.
Catalog Number: 10491-548
Supplier: Bioss


Description: PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs, PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet alpha-granules, and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-alpha and PDGFR-beta. PDGFR-alpha is a high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-beta interacts with only PDGF-BB and PDGF-AB. Recombinant Human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two beta chains (218 total amino acids).
Catalog Number: 76303-584
Supplier: PeproTech, Inc.


Description: DNA Quantitation is a very important task in DNA sample preparations for various analyses.
Catalog Number: 76485-150
Supplier: AAT BIOQUEST INC

Small Business Enterprise Minority or Woman-Owned Business Enterprise


Description: Non-clean/non sterile CSM RABS/Isolator gloves for use in 203 mm (8") ports.
Catalog Number: 76408-464
Supplier: Ansell Healthcare


Description: DNA Quantitation is a very important task in DNA sample preparations for various genomic analyses.
Catalog Number: 76484-956
Supplier: AAT BIOQUEST INC

Small Business Enterprise Minority or Woman-Owned Business Enterprise


Description: Non-slip floor signs stay down and send a distinct message. Unlike vinyl floor decals or tape, adhesive backing won't leave residue or damage floors upon removal.
Catalog Number: 76415-108
Supplier: New Pig


Description: Superior realism, reliability, and durability.
Catalog Number: 470327-390
Supplier: ELEVATE HEALTHCARE, INC. SE


Description: Countertop Signs alert and remind employees and visitors to protect themselves and prevent the spread of COVID-19, the Coronavirus, by following the preventative measures outlined.
Catalog Number: 76442-584
Supplier: ACCUFORM MANUFACTURING, INC


Description: Non-clean/non sterile CSM RABS/Isolator gloves for use in 254 mm (10") ports.
Catalog Number: 76408-474
Supplier: Ansell Healthcare


Description: Non-clean/non sterile CSM RABS/Isolator gloves for use in 305 mm (12") ports.
Catalog Number: 76408-480
Supplier: Ansell Healthcare


Description: Magid's TouchMaster is a two-piece lisle inspection glove constructed of cool and breathable cotton.
Catalog Number: 11000-250
Supplier: Magid Glove

Small Business Enterprise


Description: Lightweight pipettors are designed for the accurate, precise pipetting of solutions, reagents, acids, serums, and other liquids, and for gel-sequencing applications.
Catalog Number: 89209-932
Supplier: DWK Life Sciences (KIMBLE)

Description: Ideal for cleanroom and laboratory maintenance, these stainless steel vacuum systems feature an ULPA (Ultra Low Penetration Air) filter with 99.999% efficiency on particles as small as 0.12µm
Catalog Number: 14900-020
Supplier: Tiger-Vac International


Description: These gloves provide extreme strength and comfort.
Catalog Number: 80091-990
Supplier: Wells Lamont


Description: The tapered jaws on these pliers allow better accessibility in tight places.
Catalog Number: 76471-586
Supplier: Excelta


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