You Searched For: Antibodies

Catalog Number: (10799-868)

Supplier: Rockland Immunochemical

Description: 6X His Tag ATTO 647N conjugated Antibody as well as other Epitope tags are short peptide sequences that are easily recognized by tag-specific antibodies.  Due to their small size, epitope tags do not affect the tagged protein’s biochemical properties.   Most often sequences encoding the epitope tag are included with target DNA at the time of cloning to produce fusion proteins containing the epitope tag sequence.  This allows anti-epitope tag antibodies to serve as universal detection reagents for any tag containing protein produced by recombinant means.  This means that anti-epitope tag antibodies are a useful alternative to generating specific antibodies to identify, immunoprecipitate or immunoaffinity purify a recombinant protein.  The anti-epitope tag antibody is usually functional in a variety of antibody-dependent experimental procedures.  Expression vectors producing epitope tag fusion proteins are available for a variety of host expression systems including bacteria, yeast, insect and mammalian cells.  Rockland Immunochemicals produces anti-epitope tag antibodies against many common epitope tags including Myc, GST, GFP, 6X His, MBP, FLAG and HA. Rockland Immunochemicals also produces antibodies to other tags including FITC, Rhodamine (TRITC), DNP and biotin.

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Supplier: Tonbo Biosciences

Description: The SK1 antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

Catalog Number: (75877-358)

Supplier: MP Biomedicals

Description: Product is the lyophilized powder of goat antiserum to human secretory IgA and buffer salts.

IgA antibody is a secretory antibody found abundantly in mucous linings of gastrointestinal, respiratory and genitourinary tracts, tears and saliva. Secretory IgA contributes to the humoral defense mechanism against the pathogens on mucosal surfaces. Anti-Human IgA (α-chain specific) antibody specifically recognizes human IgA. Immunoglobulin A (IgA) is the primary antibody involved in mucosal immunity. It is identified by the presence of α-type heavy chains. IgA, which is composed of two subclasses IgA1 and IgA2, can exist in a dimeric secretory form found in mucous secretions.

The total protein is measured using the Biuret procedure, with bovine albumin as a standard. Antibody titer is standardized by equivalence-point precipitation. Each antiserum is tested for specificity at a minimum of 80 mg/mL using immunoelectrophoresis.

The antiserum is prepared by hyperimmunizing goats with highly purified human secretory IgA; antiserum is delipidated and made specific by solid-phase absorption. The resulting antiserum is dialyzed into 0.02M sodium phosphate, 0.14M sodium chloride, pH 7.3, with 0.05% sodium azide, adjusted to standard titer, filtered through a 0.22 µm filter, vialed and lyophilized.

This product is suitable for use as a precipitating antibody. It gives sharp precipitin lines in immunoelectrophoresis and immunodiffusion techniques. It is suitable for Ouchterlony double diffusion. The antibody was used for IgA quantification by ELISA in various studies. Antibody dilution of 1:4000 was used for passive hemagglutination inhibition assay.

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Catalog Number: (10801-254)

Supplier: Rockland Immunochemical

Description: F(ab')2 Cat IgG (HandL), Polyclonal antibody, Host: Rabbit, Store vial at 4degree C prior to restoration, Concentration: 10.0 mg/mL by UV absorbance at 280 nm, Application: Elisa, WB, Ihc, 20mg

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Catalog Number: (89153-518)

Supplier: Enzo Life Sciences

Description: Host: Rat, Isotype: IgM

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Supplier: Tonbo Biosciences

Description: The N418 antibody reacts with mouse CD11c, also known as integrin alpha X. This 150 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha X (CD11c) assembles with Integrin beta-2 (CD18) into a receptor complex known as CR4 which can bind and induce signaling through ICAMs and VCAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.

Supplier: Tonbo Biosciences

Description: Monoclonal Antibody Anti-Mouse LY-6G clone:1A8 Isotype:Rat IgG2a, kappa Alternative name:Gr-1 Format:PERCP-CY5.5 Concentration:0.2 mg/mL Application: Flow cytometry

Supplier: Diagnostic Biosystems

Description: This antibody reacts with a 92 kDa pro form and 86 kDa active form of MMP-9. MMPs are proteolytic enzymes capable of degrading connective tissue components. MMPs play a crucial role in tumor cell invasion and metastasis.

Supplier: Rockland Immunochemical

Description: The emission spectra for this ATTO conjugate matches the principle output wavelengths of most common fluorescence instrumentation.

Catalog Number: (RL600-401-905)

Supplier: Rockland Immunochemical

Description: This affinity purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 170 kDa in size corresponding to EGFR Protein by western blotting.

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Catalog Number: (75932-778)

Supplier: Rockland Immunochemical

Description: TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells.

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Supplier: Enzo Life Sciences

Description: The Hsp90 family of heat shock proteins represents one of the most abundantly expressed and highly conserved families of cellular chaperones whose expression can be upregulated under conditions of cellular stress, and includes cytoplasmic (Hsp90-alpha/beta), ER (grp94), and mitochondrial (TRAP1) localized members. Structurally, Hsp90 is characterized by an N-terminal ATP-binding domain, a medial substrate-binding domain, and a C-terminal dimerization motif. Hsp90 dimers function in cooperation with cochaperones (e.g. Hsp40, Hsp70, Hop, p23) to stabilize a multitude of client protein substrates, including steroid hormone receptors, protein kinases, and transcription factors. The essential binding and hydrolysis of ATP by Hsp90 is inhibited by ansamycin drugs (e.g. geldanamycin, 17-AAG) which occupy the N-terminal Hsp90 nucleotide-binding pocket. Many Hsp90 client proteins such as erbB2/Her-2, c-raf, bcr-abl, p53, and hTERT, are members of well characterized oncogenic pathways, making Hsp90 inhibitors useful anticancer agents.

Catalog Number: (RL608-1003)

Supplier: Rockland Immunochemical

Description: Secondary Goat Anti-IgG F(c) Reacts with Horse (Equine)

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Catalog Number: (RL610-4107)

Supplier: Rockland Immunochemical

Description: Anti-Mouse IgM mu heavy chain antibody is suitable for use in immunoelectrophoresis, western-blot, competitive western-blot, ELISA and competitive ELISA assays. Specific conditions for reactivity and signal detection should be optimized by the end user.

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Catalog Number: (RL600-601-400S)

Supplier: Rockland Immunochemical

Description: Antibody has been tested by ELISA and western blotting against native form phosphorylated ATM PK. 25ul

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Catalog Number: (10150-806)

Supplier: Immunoreagents

Description: ImmunoReagents is a manufacturer of quality research and production reagents for the Life Science Industries. Product lines include a wide range of antibodies used in ELISA, immunohistochemistry (IHC), western blotting, flow cytometry (FACS), immunofluorescence and microscopy.  antibodies produced cover a broad range of Immunoglobulins from various species cross absorbed to provide high specificity.  

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