You Searched For: Antibodies

Catalog Number: (RL201-401-C41S)

Supplier: Rockland Immunochemical

Description: Anti-Bovine Interferon Gamma (Rabbit) Antibody - 201-401-C41S Interferon Gamma Antibody 25Ul

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Supplier: Rockland Immunochemical

Description: This Protein-A purified antibody is suitable for ELISA and Western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 7.8 kDa in size corresponding to swine CCL4 Protein by western blotting.

Catalog Number: (RL612-105-130)

Supplier: Rockland Immunochemical

Description: Secondary Goat Anti- IgG IgA IgM Reacts with Rat

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Catalog Number: (RL600401I55)

Supplier: Rockland Immunochemical

Description: Anti-Histone H3 [Dimethyl Lys4, p Thr3] antibody is useful for Western Blot, Immunocytochemistry/Immunofluorescence, Chromatin Immunoprecipitation, and Dot Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approxi

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Catalog Number: (95045-852)

Supplier: Enzo Life Sciences

Description: The DNA damage checkpoint is a signal transduction pathway that has the ability to delay entry into mitosis. When DNA is damaged, the Check point kinases (CHKs) are known to act downstream of ATM to elicit appropriate responses such as cell cycle arrest. Chk1, for instance, is activated by ATM phosphorylation of serines 123, 178, 278, and 292 of the S phase-promoting cdc25A phosphatase and accelerates IR (ionizing radiation)induced degradation of cdc25A.

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Catalog Number: (10800-718)

Supplier: Rockland Immunochemical

Description: In yeasts, Cdc6 (Saccharomyces cerevisiae) and Cdc18 (Schizosaccharomyces pombe) associate with the origin recognition complex (ORC) proteins to render cells competent for DNA replication. Cdc6 is overexpressed in human cancers, where it has a critical regulatory role in addition to DNA replication. Yan et al. (1998) showed that Cdc6 is expressed selectively in proliferating but not quiescent mammalian cells, both in culture and within tissues in intact animals. During the transition from a growth-arrested to a proliferative state, transcription of mammalian Cdc6 is regulated by E2F proteins, as revealed by a functional analysis of the human Cdc6 promoter and by the ability of exogenously expressed E2F proteins to stimulate the endogenous Cdc6 gene. They conclude that expression of human Cdc6 is regulated in response to mitogenic signals though transcriptional control mechanisms involving E2F proteins, and that Cdc6 is required for initiation of DNA replication in mammalian cells. This antibody is suitable for researchers interested in cancer research and Cell Cycle research.

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Catalog Number: (RL807-1202)

Supplier: Rockland Immunochemical

Description: Fab Anti-Gs Hamster Igg (Handl) (Goat) Antibody Fluorescein Conjugated - 807-1202 Fab Golden Syrian Hamster Igg (Handl) Antibody Fluorescein Conjugated 1 Mg

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Catalog Number: (10050-134)

Supplier: Enzo Life Sciences

Description: The Retinoblastoma (Rb) is a tumor suppressor phosphoprotein that plays a critical role in the regulation of the cell cycle. In the absence of mitogenic signaling, Rb sequesters the transcription factor E2F within the cytosol. Upon phosphorylation, E2F is liberated from Rb and translocates to the nucleus where the latter facilitates gene transcription. Aberrations in the Rb gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.

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Supplier: Enzo Life Sciences

Description: The mammalian PDI (Protein disulfide-isomerase) family encompasses several highly divergent proteins which are involved in the processing and maturation of secretory proteins in the endoplasmic reticulum by catalyzing the rearrangement of disulfide bonds.

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Supplier: Tonbo Biosciences

Description: The NOK-1 antibody reacts with human CD178 (Fas ligand) in both membrane bound and soluble forms. Fas ligand is a 40 kDa transmembrane glycoprotein, a member of the TNF family, and is expressed by activated T and NK cells, neutrophils, and monocytes. Interactions between CD178 (Fas ligand) and CD95 (Fas) induce a program of apoptosis and play a key role in immune regulation and homeostasis. The extracellular domain of human CD178 can be cleaved from the surface by matrix metalloproteinases (MMPs) resulting in a 26 kDa soluble protein.

Supplier: Tonbo Biosciences

Description: The 104 antibody reacts with mouse CD45.2, also known as Ly5.2, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors. 

Supplier: Enzo Life Sciences

Description: Modification of proteins by addition of K63-linked polyubiquitin chains is implicated in a variety of cellular events, including DNA repair, signal transduction and receptor endocytosis.

Catalog Number: (75930-716)

Supplier: Rockland Immunochemical

Description: p62, also known as sequestosome1 (SQSTM1), is a shuttle protein transporting polyubiquitinated proteins for both proteasomal and lysosomal degradation. p62 is an integral component of inclusions in brains of various neurodegenerative disorders, including Alzheimer disease (AD) neurofibrillary tangles (NFTs) and Lewy bodies in Parkinson disease. p62 plays an important role in the protection of cells from the toxicity of misfolded proteins by enhancing aggregate formation especially in the later stages. Phosphorylation of Ser28 has recently been demonstrated to be related to the pathogenesis of Parkinson’s disease. p62 pS28 Antibody is ideal for researchers interested in neuroscience research.

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Catalog Number: (10152-116)

Supplier: Immunoreagents

Description: The ImmunoReagents' DyLight® 488 conjugates provide exceptional performance for a wide array of fluorescence-base applications at a lower cost than other 488-range dyes. DyLight® 488 shows greater photostability than traditional fluorescein-based dyes and has a greater range of pH insensitivity (pH 4-9). DyLight® 488 conjugates are available for use in fluorescence microscopy, flow cytometry, Western blotting, ELISA, high-content screening and other array platforms. Excitation/Emission = 493nm / 518nm Emission Color = Green (Similar Dyes: Alexa Fluor 488, Cy2, FITC)

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Catalog Number: (RL209-406-B50)

Supplier: Rockland Immunochemical

Description: This purified antibody has been tested for use in ELISA and western blotting. By western blot a band approximately 18 kDa in size corresponding to mature human IL-32a Protein is expected in the appropriate cell lysate or extract.

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Catalog Number: (75935-404)

Supplier: Rockland Immunochemical

Description: STIM2 antibody detects human STIM2. In T lymphocytes, the sole pathway for Ca++ entry following antigen-receptor binding is through store-operated Ca++-release-activated Ca++ (CRAC) channels. These channels are made up of the pore-forming subunit ORAI1 and the stromal interaction molecule 1 (STIM1), a protein that functions as a Ca++ sensor and activates the CRAC channels, migrating to the plasma membrane from endoplasmic reticulum (ER)-like sites which act as the Ca++ store. A related molecule, STIM2, acts to inhibit the STIM1-mediated store-operated Ca++ entry, and can form complexes with STIM1, suggesting they may play a coordinated role in controlling Ca++ entry. At least three isoforms of STIM2 are known to exist. This STIM2 antibody is predicted to have no cross-reactivity to STIM1. Anti-STIM2 is ideal for investigators involved enzyme research.

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