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Description: Neuroligins are a family of plasma membrane proteins that possess an N-terminal hydrophobic domain, a large esterase homology domain, a single transmembrane region, a short cytoplasmic domain, and an EF-hand binding domain (1,2). Members of the neuroligin family include Neuroligin 1, Neuroligin 2 and Neuroligin 3. Neuroligins are expressed in excitatory neuronal synaptic clefts. Neuroligins play a role in the formation and remodeling of CNS synapses by binding to b-neurexins, a family of neuronal cell surface proteins. Neuroexin 1b binds to the EF-hand domain of Neuroligin 1 and requires calcium ion. Neuroligins also bind to PSD-95, which may recruit ion channels and neurotransmitter receptors to the synapses.
Catalog Number: 10248-612
Supplier: Bioss


Description: Neuroligins are a family of plasma membrane proteins that possess an N-terminal hydrophobic domain, a large esterase homology domain, a single transmembrane region, a short cytoplasmic domain, and an EF-hand binding domain (1,2). Members of the neuroligin family include Neuroligin 1, Neuroligin 2 and Neuroligin 3. Neuroligins are expressed in excitatory neuronal synaptic clefts. Neuroligins play a role in the formation and remodeling of CNS synapses by binding to b-neurexins, a family of neuronal cell surface proteins. Neuroexin 1b binds to the EF-hand domain of Neuroligin 1 and requires calcium ion. Neuroligins also bind to PSD-95, which may recruit ion channels and neurotransmitter receptors to the synapses.
Catalog Number: 10248-440
Supplier: Bioss


Description: RCV1 is a member of the recoverin family of neuronal calcium sensors. RCV1 contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy.The protein encoded by this gene contains four calcium-binding EF-hand domains and belongs to the recoverin family of neuronal calcium sensors. Recoverin may prolong the termination of the phototransduction cascade by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy; an autoimmune disease of the retina caused by a tumor in another tissue.
Catalog Number: 10107-042
Supplier: Prosci


Description: Flex-Tube® microtubes (1.5 ml) are designed for seamless one-handed operation with an easy-to-open, securely closing tube design. Perfect for sample preparation, centrifugation, and storage, these tubes will effortlessly integrate into workflows for efficient and reliable performance.
Catalog Number: 20901-424
Supplier: Eppendorf

Product available on GSA Advantage®


Description: <B>Protect your fingers without gloves.</B><BR>This self-adhering tape maintains an unimpaired sense of touch, yet prevents hand and finger injuries from sharp edges, hot surfaces, or rough materials.
Catalog Number: 470150-976
Supplier: GENERAL BANDAGES INC.


Description: The Neutralization by the Drop Titration Method Kit contains an easy and hands-on titration experiment.
Catalog Number: 470200-526
Supplier: Kemtec


Description: The International DS-500 Diamond series 500 W type 3 V converters are 220 Electronics best voltage transformers. They are thoroughly tested to the highest workmanship and material standards and hand soldering insures to meet U.S Military specifications.
Catalog Number: 470061-802
Supplier: INTERNATIONAL VIDEO & ELECTRONICS


Description: This hand held connector cleaner is a great alternative to alcohol or solvent and wipes.
Catalog Number: 76250-014
Supplier: FIBER INSTRUMENT SALES INC. TE


Description: This durable handle accommodates No
Catalog Number: 25856-023
Supplier: Aspen Surgical Products


Description: Secreted Protein Acidic and Rich in Cysteine (SPARC) is a secreted, evolutionarily conserved collagen-binding glycoprotein and belongs to the SPARC family. SPARC has 286 amino acids and contains an EF-hand in C-termina domain, a follistatin-like domain with Kazal-like sequences. There are two calcium binding sites, one binds 5 - 8 Ca2+ with a low affinity and other on an EF-hand loop that binds a Ca2+ ion with a high affinity. It is highly expressed in tissues undergoing morphogenesis, remodeling and wound repair. SPARC regulate cell growth through interactions with the extracellular matrix (ECM) and cytokines. SPARC bind to numerous proteins of the ECM, affect ECM protein expression, influence cellular adhesion and migration, and modulate growth factor-induced cell proliferation and angiogenesis. SPARC also binds several types of collagen, albumin, thrombospondin, PDGF and cell membranes.
Catalog Number: 75789-386
Supplier: Prosci


Description: Flextril™ gloves are a hand protection solution designed to provide fivefold performance – high chemical protection, reliable cut resistance, great wet and dry grip, enhanced dexterity, and improved comfort. Additionally, all glove models feature a printed QR code, providing all of the necessary performance data at the wearer's fingertips.
Catalog Number: 76595-214
Supplier: Honeywell Safety Products


Description: CALML6, also named as CAGLP, CALGP , belongs to the calmodulin family and Calglandulin subfamily. It contains 4 EF-hand domains. The antibody is specific to CALML6.
Catalog Number: 10083-988
Supplier: Proteintech


Description: Feature stainless steel blades sonically welded to 70% recycled plastic handles
Catalog Number: 500024-622
Supplier: Janitorial Supplies

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Description: Lab Alert not only safeguards product and assets, but it also frees up valuable staff by eliminating daily manual collection, recording, and storage of data, allowing them to focus on the tasks at hand.
Catalog Number: 10119-678
Supplier: PHC Corporation

Product available on GSA Advantage®


Description: DLX5 is a member of a homeobox transcription factor family. DLX5 may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation.This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation.
Catalog Number: 10107-216
Supplier: Prosci


Description: The ZFHX1B gene is a member of the delta-EF1/Zfh1 family of 2-handed zinc finger/homeodomain proteins. ZFHX1B is strongly transcribed at an early stage in the developing peripheral and central nervous systems of both mice and humans, in all neuronal regions of the brains of 25-week human fetuses and adult mice, and in numerous nonneural tissues.The SMADIP1 gene (also known as SIP1) is a member of the delta-EF1 (ZEB1; MIM 189909)/Zfh1 family of 2-handed zinc finger/homeodomain proteins. SMADIP1 interacts with receptor-mediated, activated full-length SMADs (see MIM 605568) (Verschueren et al., 1999 [PubMed 10400677]).
Catalog Number: 10105-712
Supplier: Prosci


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