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Catalog Number: (89367-214)
Supplier: Genetex
Description: AKT (Protein Kinase B, PKB) was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold; overexpression or inappropriate activation of Akt has been seen in many types of cancer. AKT mediates many of the downstream events of phosphatidylinositol 3 kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI 3 kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus. AKT has two main roles: (i) inhibition of apoptosis; (ii) promotion of proliferation.


Catalog Number: (89363-716)
Supplier: Genetex
Description: Rabbit polyclonal antibody to Akt (phospho Ser473)


Supplier: Promega Corporation
Description: The Reverse Transcription System provides reagents to efficiently reverse transcribe RNA into cDNA in fifteen minutes.
Catalog Number: (89360-292)
Supplier: Genetex
Description: The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin-dependent kinase, ERK2 and C-Jun N-terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.


Catalog Number: (89233-908)
Supplier: G-Biosciences
Description: LabSafe™ Nucleic Acid Stain is a safe nucleic acid stain for the visualization of double-stranded DNA, single-stranded DNA, and RNA in agarose gels.


Catalog Number: (10275-930)
Supplier: Bioss
Description: DDX3 is involved in RNA metabolism. Two DDX3 paralogs are found in humans; DDX3X is encoded by a gene found on the X chromosome while DDX3Y is encoded by a gene on the Y chromosome. DDX3Y is exclusively expressed in testis and is required for normal spermatogenesis. DDX3X is ubiquitously expressed and predominantly localizes to the nuclear speckles, participating in RNA splicing, transcription, translation initiation, mRNA transport and cell cycle regulation. DDX3X also partakes in HIV-1 replication and hepatitis C viral infections.


Catalog Number: (89360-856)
Supplier: Genetex
Description: The Raf kinases are important inter-mediates in signal transduction. Raf-l proteins have intrinsic serine/threonine kinase activity. Interaction between Ras proteins and Raf proteins results in Raf-mediated phosphorylation and activation of MEK (also known as MAP kinase kinase).


Catalog Number: (12001-804)
Supplier: Lonza
Description: GelStar is a sensitive fluorescent stain for detecting both DNA and RNA.

Supplier: Bachem Americas
Description: A high level of inhibition of virus replication was obtained with this peptide, which resembles a region of a viral polypeptide.

Catalog Number: (89352-328)
Supplier: Genetex
Description: Rabbit polyclonal to c-Fos


Catalog Number: (89355-776)
Supplier: Genetex
Description: Rat monoclonal antibody [JAC6] to c-Myc


Supplier: GENOSENSOR CORPORATION
Description: Perform loop-mediated isothermal amplification (LAMP) without the need for expensive equipment, even from home.

Catalog Number: (89355-418)
Supplier: Genetex
Description: Mouse monoclonal [9E10] to c-Myc (FITC)


Catalog Number: (89353-666)
Supplier: Genetex
Description: HRP Conjugated Chicken anti C - Myc


Catalog Number: (89328-960)
Supplier: Genetex
Description: Chicken polyclonal antibody to Raf1


Catalog Number: (89355-424)
Supplier: Genetex
Description: Mouse monoclonal [9E10] to c - Myc (HRP)


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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