You Searched For: viral+rna

Supplier: Promega Corporation

Description: The ReliaPrep FFPE Total RNA Miniprep System provides a complete, all-inclusive method for purification of quality total RNA from formalin-fixed paraffin-embedded tissue without using hazardous solvents or overnight digestion.

SDS Certificates

Catalog Number: (76117-304)

Supplier: Bioss

Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template. At the start of transcription, a single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol II. A bridging helix emanates from RPB1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol II by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition. During transcription elongation, Pol II moves on the template as the transcript elongates. Elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of Pol II largest subunit (RPB1), which serves as a platform for assembly of factors that regulate transcription initiation, elongation, termination and mRNA processing. Acts as a RNA-dependent RNA polymerase when associated with small delta antigen of Hepatitis delta virus, acting both as a replicate and transcriptase for the viral RNA circular genome.

Sale

Supplier: Sino Biological

Description: Produced in rabbits immunized with purified, recombinant T7 RNA Polymerase. The specific IgG was purified by T7 RNA Polymerase affinity chromatography.

Catalog Number: (BJSR674-20)

Supplier: Honeywell Research Chemicals

Description: Burdick & Jackson® BioSyn® reagents & solvents for DNA/RNA synthesis

SDS Certificates Sale

Catalog Number: (76117-418)

Supplier: Bioss

Description: RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The largest subunit of Pol II (referred to as RPB1 or RPB205) is a 1,840 amino acid protein that contains one C2H2-type zinc finger and a C-terminal domain comprised of several heptapeptide repeats. Although Pol II function requires the cooperation of all twelve subunits, the largest subunit conveys Pol II catalytic activity and, together with the second largest subunit, forms the active center of the Pol II enzyme. Additionally, the large subunit participates in forming the DNA-binding domain of Pol II, a groove that is necessary for transcription of the DNA template. Without proper function of the large subunit, mRNA synthesis and subsequent transcription elongation cannot occur.

Sale

Supplier: PerkinElmer

Description: The NEXTFLEX™ small RNA-sequence kit V4 enables labs to reduce bias in their Illumina® small RNA-sequence workflows while leveraging a completely gel-free protocol, even with low input samples.

Catalog Number: (102867-676)

Supplier: R&D Systems

Description: The Recombinant Viral CCI Fc Chimera (CHO-expressed) Protein from R&D Systems is derived from CHO. The Recombinant Viral CCI Fc Chimera (CHO-expressed) Protein has been validated for the following applications: Bioactivity.

Sale

Supplier: Adipogen

Description: Cold-inducible RNA-binding protein (CIRP) is from the family of cold shock proteins that plays a protective role in the genotoxic and cold stress response. CIRBP functions as an RNA chaperone to facilitate translation and to stabilize transcripts of genes involved in cell survival. CIRP (human) is a 172-aa nuclear protein consisting of one amino-terminal consensus sequence RNA-binding domain and one carboxyl-terminal glycine-rich domain. When overexpressed, CIRP promotes assembly of stress granules (SGs). CIRP is constitutively expressed at low levels in various tissues becoming up-regulated during mild hypothermia as well as exposure to UV irradiation and hypoxia. CIRP is also found extracellularly, where it acts as a proinflammatory mediator causing deleterious effects during hemorrhagic and septic shock.

Supplier: Honeywell Research Chemicals

Description: Burdick & Jackson® BioSyn® reagents & solvents for DNA/RNA synthesis

Certificates

Catalog Number: (ABCA_AB264350-100U)

Supplier: ABCAM INC.

Description: Anti-RNA polymerase II RPB1 Rabbit Polyclonal Antibody

New Product Sale

Catalog Number: (76116-574)

Supplier: Bioss

Description: RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The largest subunit of Pol II (referred to as RPB1 or RPB205) is a 1,840 amino acid protein that contains one C2H2-type zinc finger and a C-terminal domain comprised of several heptapeptide repeats. Although Pol II function requires the cooperation of all twelve subunits, the largest subunit conveys Pol II catalytic activity and, together with the second largest subunit, forms the active center of the Pol II enzyme. Additionally, the large subunit participates in forming the DNA-binding domain of Pol II, a groove that is necessary for transcription of the DNA template. Without proper function of the large subunit, mRNA synthesis and subsequent transcription elongation cannot occur.

Sale

Catalog Number: (102205-000)

Supplier: Novus Biologicals

Description: The RNA polymerase I termination factor Antibody from Novus Biologicals is a rabbit polyclonal antibody to RNA polymerase I termination factor. This antibody reacts with human. The RNA polymerase I termination factor Antibody has been validated for the following applications: Western Blot.

Sale

Supplier: Honeywell Research Chemicals

Description: Burdick & Jackson® BioSyn® reagents & solvents for DNA/RNA synthesis

SDS Certificates

Supplier: Honeywell Research Chemicals

Description: Burdick & Jackson® BioSyn® reagents & solvents for DNA/RNA synthesis

SDS Certificates

Catalog Number: (ABCA_AB171119-100U)

Supplier: ABCAM INC.

Description: Anti-ribosomal RNA Mouse Monoclonal Antibody [clone: Y10B]

New Product Sale

Catalog Number: (102139-464)

Supplier: Novus Biologicals

Description: RUSC1 antisense RNA 1 Overexpression Lysate (Adult Normal)

Sale